5I96
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![BU of 5i96 by Molmil](/molmil-images/mine/5i96) | Crystal Structure of Human Mitochondrial Isocitrate Dehydrogenase (IDH2) R140Q Mutant Homodimer in Complex with AG-221 (Enasidenib) Inhibitor. | Descriptor: | 2-methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol, ACETATE ION, CALCIUM ION, ... | Authors: | Wei, W, Zhang, B, Jin, L, Jiang, F, DeLaBarre, B, Travins, J.A, Padyana, A.K. | Deposit date: | 2016-02-19 | Release date: | 2017-03-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations. Cancer Discov, 7, 2017
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1MSB
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7DC1
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![BU of 7dc1 by Molmil](/molmil-images/mine/7dc1) | |
5HMG
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![BU of 5hmg by Molmil](/molmil-images/mine/5hmg) | REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | Authors: | Weis, W.I, Bruenger, A.T, Skehel, J.J, Wiley, D.C. | Deposit date: | 1989-09-11 | Release date: | 1991-01-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Refinement of the influenza virus hemagglutinin by simulated annealing. J.Mol.Biol., 212, 1990
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5F0W
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4JA8
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![BU of 4ja8 by Molmil](/molmil-images/mine/4ja8) | Complex of Mitochondrial Isocitrate Dehydrogenase R140Q Mutant with AGI-6780 Inhibitor | Descriptor: | 1-[5-(cyclopropylsulfamoyl)-2-thiophen-3-yl-phenyl]-3-[3-(trifluoromethyl)phenyl]urea, CALCIUM ION, GLYCEROL, ... | Authors: | Wei, W, Chen, L, Wu, M, Jiang, F, Travins, J, Qian, K, DeLaBarre, B. | Deposit date: | 2013-02-18 | Release date: | 2013-04-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. Science, 340, 2013
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4Y2I
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![BU of 4y2i by Molmil](/molmil-images/mine/4y2i) | Gold ion bound to GolB | Descriptor: | GOLD ION, Putative metal-binding transport protein | Authors: | Wei, W, Wang, F, Ma, L, Zhao, J. | Deposit date: | 2015-02-10 | Release date: | 2016-02-10 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB J.Am.Chem.Soc., 137, 2015
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5F0U
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![BU of 5f0u by Molmil](/molmil-images/mine/5f0u) | Crystal structure of Gold binding protein | Descriptor: | Putative copper chaperone, SILVER ION | Authors: | Wei, W, Wang, F, Zhao, J. | Deposit date: | 2015-11-28 | Release date: | 2017-01-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structure of tetrasilver bound to GolB at 1.70 Angstroms resolution To Be Published
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4Y2K
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![BU of 4y2k by Molmil](/molmil-images/mine/4y2k) | reduced form of apo-GolB | Descriptor: | Putative metal-binding transport protein | Authors: | Wei, W, Wang, F, Ma, L, Zhao, J. | Deposit date: | 2015-02-10 | Release date: | 2016-02-10 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB J.Am.Chem.Soc., 137, 2015
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4Y2M
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![BU of 4y2m by Molmil](/molmil-images/mine/4y2m) | apo-GolB protein | Descriptor: | GOLD ION, Putative metal-binding transport protein | Authors: | Wei, W, Zhao, J, Wang, F. | Deposit date: | 2015-02-10 | Release date: | 2016-02-10 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB J.Am.Chem.Soc., 137, 2015
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5O51
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![BU of 5o51 by Molmil](/molmil-images/mine/5o51) | AfRom2 CNH domain | Descriptor: | Rho guanyl nucleotide exchange factor (Rom2), putative | Authors: | Wei, W, van Aalten, D. | Deposit date: | 2017-05-31 | Release date: | 2018-06-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Rom2 CNH domain from Aspergillus fumigatus is an atypical seven-bladed WD-40 protein To Be Published
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5ZVP
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![BU of 5zvp by Molmil](/molmil-images/mine/5zvp) | Aspergillus fumigatus Rho1 F25N | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase Rho1, ... | Authors: | Wei, W.F, Van Aalten, D.M.F. | Deposit date: | 2018-05-12 | Release date: | 2019-05-15 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Aspergillus fumigateurs Rho1 F25N To Be Published
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1RTM
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4HMG
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![BU of 4hmg by Molmil](/molmil-images/mine/4hmg) | REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, CHAIN HA1, ... | Authors: | Weis, W.I, Bruenger, A.T, Skehel, J.J, Wiley, D.C. | Deposit date: | 1989-09-11 | Release date: | 1991-01-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Refinement of the influenza virus hemagglutinin by simulated annealing. J.Mol.Biol., 212, 1990
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6PWS
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![BU of 6pws by Molmil](/molmil-images/mine/6pws) | |
6PWT
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6PWR
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![BU of 6pwr by Molmil](/molmil-images/mine/6pwr) | |
6BFI
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![BU of 6bfi by Molmil](/molmil-images/mine/6bfi) | |
7JUC
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![BU of 7juc by Molmil](/molmil-images/mine/7juc) | |
7L66
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7L62
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7L63
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![BU of 7l63 by Molmil](/molmil-images/mine/7l63) | |
7L64
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7L65
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7L68
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![BU of 7l68 by Molmil](/molmil-images/mine/7l68) | |