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PDB: 659 件

6CB9
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BU of 6cb9 by Molmil
Segment AALQSS from the low complexity domain of TDP-43, residues 328-333
分子名称: AALQSS
著者Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S.
登録日2018-02-02
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
6CEW
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BU of 6cew by Molmil
Segment AMMAAA from the low complexity domain of TDP-43, residues 321-326
分子名称: AMMAAA
著者Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S.
登録日2018-02-12
公開日2018-04-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
6CU8
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BU of 6cu8 by Molmil
Alpha Synuclein fibril formed by full length protein - Twister Polymorph
分子名称: Alpha-synuclein
著者Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
7LUX
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BU of 7lux by Molmil
AALALL segment from the Nucleoprotein of SARS-CoV-2, residues 217-222, crystal form 2
分子名称: Nucleoprotein AALALL, TETRAETHYLENE GLYCOL
著者Lu, J, Zee, C.-T, Sawaya, M.R, Rodriguez, J.A, Eisenberg, D.S.
登録日2021-02-23
公開日2021-03-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.303 Å)
主引用文献Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2.
Biorxiv, 2021
7LV2
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BU of 7lv2 by Molmil
GSQASS segment from the Nucleoprotein of SARS-CoV-2, residues 179-184
分子名称: Nucleoprotein GSQASS
著者Hou, K, Sawaya, M.R, Eisenberg, D.S, Cascio, D.
登録日2021-02-23
公開日2021-03-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.301 Å)
主引用文献Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2.
Biorxiv, 2021
7LTU
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BU of 7ltu by Molmil
AALALL SEGMENT FROM THE NUCLEOPROTEIN OF SARS-COV-2, RESIDUES 217-222, CRYSTAL FORM 1
分子名称: AALALL SEGMENT FROM THE NUCLEOPROTEIN OF SARS-COV-2,RESIDUES 217-222, trifluoroacetic acid
著者Zee, C.-T, Sawaya, M.R, Rodriguez, J.A, Eisenberg, D.S.
登録日2021-02-20
公開日2021-03-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.122 Å)
主引用文献Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2.
Biorxiv, 2021
6DIX
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BU of 6dix by Molmil
NFVFGT segment from Human Immunoglobulin Light-Chain Variable Domain, Residues 98-103, assembled as an amyloid fibril
分子名称: NFVFGT Immunoglobulin Light-Chain Variable Domain
著者Brumshtein, B, Esswein, S.R, Sawaya, M.R, Eisenberg, D.S.
登録日2018-05-23
公開日2018-10-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis.
J. Biol. Chem., 293, 2018
5WIA
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BU of 5wia by Molmil
Crystal structure of the segment, GNNSYS, from the low complexity domain of TDP-43, residues 370-375
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Trinh, H, Sawaya, M.R, Eisenberg, D.S.
登録日2017-07-18
公開日2018-04-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.002 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5WKD
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BU of 5wkd by Molmil
Crystal structure of the segment, GNNQGSN, from the low complexity domain of TDP-43, residues 300-306
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Trinh, H, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
登録日2017-07-25
公開日2018-04-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
1ZQW
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BU of 1zqw by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF CSCL (150 MILLIMOLAR)
分子名称: DNA POLYMERASE BETA
著者Pelletier, H, Sawaya, M.R.
登録日1996-04-19
公開日1996-11-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis.
Biochemistry, 35, 1996
5WHP
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BU of 5whp by Molmil
Crystal structure of the segment, NFGTFS, from the A315T familial variant of the low complexity domain of TDP-43, residues 312-317
分子名称: Segment of TAR DNA-binding protein 43
著者Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
登録日2017-07-17
公開日2018-05-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
1ZQU
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BU of 1zqu by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF ARTIFICIAL MOTHER LIQUOR
分子名称: DNA POLYMERASE BETA
著者Pelletier, H, Sawaya, M.R.
登録日1996-04-19
公開日1996-11-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis.
Biochemistry, 35, 1996
1ZQZ
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BU of 1zqz by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF MNCL2 (50 MILLIMOLAR)
分子名称: DNA POLYMERASE BETA, MANGANESE (II) ION
著者Pelletier, H, Sawaya, M.R.
登録日1996-04-19
公開日1996-11-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis.
Biochemistry, 35, 1996
5WIQ
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BU of 5wiq by Molmil
Crystal structure of the segment, GFNGGFG, from the low complexity domain of TDP-43, residues 396-402
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
登録日2017-07-19
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
8SPA
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BU of 8spa by Molmil
Structural insights into cellular control of the human CPEB3 prion, functionally regulated by a labile-amyloid-forming segment
分子名称: Cytoplasmic polyadenylation element-binding protein 3
著者Flores, M.D, Sawaya, M.R, Boyer, D.R, Zink, S, Fioriti, L, Rodriguez, J.A.
登録日2023-05-02
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of a reversible amyloid fibril formed by the CPEB3 prion-like domain reveals a core sequence involved in translational regulation
To Be Published
6UG3
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BU of 6ug3 by Molmil
C3 symmetric peptide design number 1, Sporty, crystal form 1
分子名称: C3-1, Sporty, crystal form 1, ...
著者Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D.
登録日2019-09-25
公開日2020-12-02
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
6UGC
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BU of 6ugc by Molmil
C3 symmetric peptide design number 3
分子名称: C3-3 cyclic peptide design, CADMIUM ION, SODIUM ION
著者Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D.
登録日2019-09-26
公開日2020-12-02
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
1ZQY
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BU of 1zqy by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF MGCL2 (50 MILLIMOLAR)
分子名称: DNA POLYMERASE BETA
著者Pelletier, H, Sawaya, M.R.
登録日1996-04-19
公開日1996-11-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis.
Biochemistry, 35, 1996
1ZQX
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BU of 1zqx by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF KCL (150 MILLIMOLAR)
分子名称: DNA POLYMERASE BETA
著者Pelletier, H, Sawaya, M.R.
登録日1996-04-19
公開日1996-11-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis.
Biochemistry, 35, 1996
6UUR
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BU of 6uur by Molmil
Human prion protein fibril, M129 variant
分子名称: Major prion protein
著者Glynn, C, Sawaya, M.R, Ge, P, Zhou, Z.H, Rodriguez, J.A.
登録日2019-10-31
公開日2020-04-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.
Nat.Struct.Mol.Biol., 27, 2020
1ZQV
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BU of 1zqv by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF CACL2 (150 MILLIMOLAR)
分子名称: CALCIUM ION, DNA POLYMERASE BETA
著者Pelletier, H, Sawaya, M.R.
登録日1996-04-19
公開日1996-11-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis.
Biochemistry, 35, 1996
7MGP
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BU of 7mgp by Molmil
CmcA from Type II Cut MCP
分子名称: BMC domain-containing protein
著者Ochoa, J.M, Escoto, X, Sawaya, M.R, Yeates, T.O.
登録日2021-04-13
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural characterization of hexameric shell proteins from two types of choline-utilization bacterial microcompartments
Acta Crystallogr.,Sect.F, 77, 2021
7MPW
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BU of 7mpw by Molmil
CmcB from Type II Cut MCP
分子名称: BMC domain-containing protein
著者Ochoa, J.M, Marshall, J.D, Sawaya, M.R, Yeates, T.O.
登録日2021-05-05
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献Structural characterization of hexameric shell proteins from two types of choline-utilization bacterial microcompartments
Acta Crystallogr.,Sect.F, 77, 2021
7MN4
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BU of 7mn4 by Molmil
CmcB E35G mutant from Type II Cut MCP
分子名称: BMC domain-containing protein
著者Ochoa, J.M, Mijares, O, Sawaya, M.R, Yeates, T.O.
登録日2021-04-30
公開日2021-09-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural characterization of hexameric shell proteins from two types of choline-utilization bacterial microcompartments
Acta Crystallogr.,Sect.F, 77, 2021
5WKB
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BU of 5wkb by Molmil
MicroED structure of the segment, NFGEFS, from the A315E familial variant of the low complexity domain of TDP-43, residues 312-317
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
登録日2017-07-24
公開日2018-05-23
最終更新日2024-03-13
実験手法ELECTRON CRYSTALLOGRAPHY (1 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018

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