5DZO
 
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3IA5
 | | Moritella profunda dihydrofolate reductase (DHFR) | | 分子名称: | Dihydrofolate reductase, PHOSPHATE ION | | 著者 | Hay, S, Evans, R.M, Levy, C, Wang, X, Loveridge, E.J, Leys, D, Allemann, R.K, Scrutton, N.S. | | 登録日 | 2009-07-13 | | 公開日 | 2009-07-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Are the Catalytic Properties of Enzymes from Piezophilic Organisms Pressure Adapted?
Chembiochem, 10, 2009
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3IPZ
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4GHQ
 | | Crystal structure of EV71 3C proteinase | | 分子名称: | 3C proteinase | | 著者 | Chen, C, Wu, C, Cai, Q, Li, N, Peng, X, Cai, Y, Yin, K, Chen, X, Wang, X, Zhang, R, Liu, L, Chen, S, Li, J, Lin, T. | | 登録日 | 2012-08-08 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
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4GHT
 | | Crystal structure of EV71 3C proteinase in complex with AG7088 | | 分子名称: | 3C proteinase, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | | 著者 | Chen, C, Wu, C, Cai, Q, Li, N, Peng, X, Cai, Y, Yin, K, Chen, X, Wang, X, Zhang, R, Liu, L, Chen, S, Li, J, Lin, T. | | 登録日 | 2012-08-08 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
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6A67
 | | Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody FLD21.140 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FLD21.140 Heavy Chain, FLD21.140 Light Chain, ... | | 著者 | Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X. | | 登録日 | 2018-06-26 | | 公開日 | 2018-08-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Complementary recognition of the receptor-binding site of highly pathogenic H5N1 influenza viruses by two human neutralizing antibodies.
J. Biol. Chem., 293, 2018
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7VLM
 | | crystal structure of anti-CRISPR protein AcrIIA18 | | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, H2C7, ... | | 著者 | Zhang, H, Wang, X.S, Li, X.Z. | | 登録日 | 2021-10-04 | | 公開日 | 2021-12-01 | | 最終更新日 | 2023-07-05 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Inhibition mechanisms of CRISPR-Cas9 by AcrIIA17 and AcrIIA18
Nucleic Acids Res., 50, 2022
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5YFP
 | | Cryo-EM Structure of the Exocyst Complex | | 分子名称: | Exocyst complex component EXO70, Exocyst complex component EXO84, Exocyst complex component SEC10, ... | | 著者 | Mei, K, Li, Y, Wang, S, Shao, G, Wang, J, Ding, Y, Luo, G, Yue, P, Liu, J.J, Wang, X, Dong, M.Q, Guo, W, Wang, H.W. | | 登録日 | 2017-09-21 | | 公開日 | 2018-01-31 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM structure of the exocyst complex
Nat. Struct. Mol. Biol., 25, 2018
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3SLU
 | | Crystal structure of NMB0315 | | 分子名称: | M23 peptidase domain protein, NICKEL (II) ION | | 著者 | Shen, Y, Wang, X, Yang, X, Xu, H. | | 登録日 | 2011-06-26 | | 公開日 | 2012-02-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Crystal structure of outer membrane protein NMB0315 from Neisseria meningitidis.
Plos One, 6, 2011
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7F7E
 | | SARS-CoV-2 S protein RBD in complex with A5-10 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of A5-10 Fab, Light chain of A5-10 Fab, ... | | 著者 | Dou, Y, Wang, X, Wang, K, Liu, P, Lu, B. | | 登録日 | 2021-06-29 | | 公開日 | 2022-02-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Etesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants.
Emerg Microbes Infect, 11, 2022
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5YWO
 | | Structure of JEV-2F2 Fab complex | | 分子名称: | 2F2 heavy chain, 2F2 light chain, JEV E protein, ... | | 著者 | Qiu, X, Lei, Y.F, Yang, P, Gao, Q, Wang, N, Cao, L, Yuan, S, Wang, X, Xu, Z.K, Rao, Z. | | 登録日 | 2017-11-29 | | 公開日 | 2018-03-21 | | 最終更新日 | 2018-09-12 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
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8GNA
 | | Structure of the SbCas7-11-crRNA-NTR complex | | 分子名称: | RAMP superfamily protein, RNA (32-MER), RNA (5'-R(P*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*GP*U)-3'), ... | | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | | 登録日 | 2022-08-23 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Target RNA-guided protease activity in type III-E CRISPR-Cas system.
Nucleic Acids Res., 50, 2022
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8GU6
 | | Structure of the SbCas7-11-crRNA-NTR-Csx29 complex | | 分子名称: | CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... | | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | | 登録日 | 2022-09-10 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Target RNA-guided protease activity in type III-E CRISPR-Cas system.
Nucleic Acids Res., 50, 2022
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5YWF
 | | Crystal structure of 2H4 Fab | | 分子名称: | 2H4 heavy chain, 2H4 light chain | | 著者 | Qiu, X, Lei, Y, Yang, P, Gao, Q, Wang, N, Cao, L, Wang, X, Xu, Z.K, Rao, Z. | | 登録日 | 2017-11-29 | | 公開日 | 2018-03-21 | | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | | 主引用文献 | Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
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5BYZ
 | | ERK5 in complex with small molecule | | 分子名称: | 4-({5-fluoro-4-[2-methyl-1-(propan-2-yl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)-N-[2-(piperidin-1-yl)ethyl]benzamide, GLYCEROL, Mitogen-activated protein kinase 7 | | 著者 | Chen, H, Tucker, J, Wang, X, Gavine, P.R, Philips, C, Augustin, M.A, Schreiner, P, Steinbacher, S, Preston, M, Ogg, D. | | 登録日 | 2015-06-11 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Discovery of a novel allosteric inhibitor-binding site in ERK5: comparison with the canonical kinase hinge ATP-binding site.
Acta Crystallogr D Struct Biol, 72, 2016
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5BYY
 | | ERK5 IN COMPLEX WITH SMALL MOLECULE | | 分子名称: | 2-{[2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Mitogen-activated protein kinase 7 | | 著者 | Chen, H, Tucker, J, Wang, X, Gavine, P.R, Philips, C, Augustin, M.A, Schreiner, P, Steinbacher, S, Preston, M, Ogg, D. | | 登録日 | 2015-06-11 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Discovery of a novel allosteric inhibitor-binding site in ERK5: comparison with the canonical kinase hinge ATP-binding site.
Acta Crystallogr D Struct Biol, 72, 2016
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6DII
 | | Structure of Arabidopsis Fatty Acid Amide Hydrolase in Complex with methyl linolenyl fluorophosphonate | | 分子名称: | Fatty acid amide hydrolase, methyl-9Z,12Z,15Z-octadecatrienylphosphonofluoridate | | 著者 | Aziz, M, Wang, X, Tripathi, A, Bankaitis, V, Chapman, K.D. | | 登録日 | 2018-05-23 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides.
J.Biol.Chem., 294, 2019
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4ZP0
 | | Crystal structure of E. coli multidrug transporter MdfA in complex with deoxycholate | | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, LAURYL DIMETHYLAMINE-N-OXIDE, Multidrug transporter MdfA | | 著者 | Zhang, X.C, Heng, J, Zhao, Y, Wang, X. | | 登録日 | 2015-05-07 | | 公開日 | 2015-08-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Substrate-bound structure of the E. coli multidrug resistance transporter MdfA
Cell Res., 25, 2015
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6DHV
 | | Structure of Arabidopsis Fatty Acid Amide Hydrolase | | 分子名称: | Fatty acid amide hydrolase | | 著者 | Aziz, M, Wang, X, Tripathi, A, Bankaitis, V, Chapman, K.D. | | 登録日 | 2018-05-21 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides.
J.Biol.Chem., 294, 2019
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4ZOW
 | | Crystal structure of E. coli multidrug transporter MdfA in complex with chloramphenicol | | 分子名称: | CHLORAMPHENICOL, Multidrug transporter MdfA | | 著者 | Zhang, X.C, Heng, J, Zhao, Y, Wang, X. | | 登録日 | 2015-05-07 | | 公開日 | 2015-08-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Substrate-bound structure of the E. coli multidrug resistance transporter MdfA
Cell Res., 25, 2015
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4ZP2
 | | Crystal structure of E. coli multidrug transporter MdfA in complex with n-dodecyl-N,N-dimethylamine-N-oxide | | 分子名称: | LAURYL DIMETHYLAMINE-N-OXIDE, Multidrug transporter MdfA | | 著者 | Zhang, X.C, Heng, J, Zhao, Y, Wang, X. | | 登録日 | 2015-05-07 | | 公開日 | 2015-08-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Substrate-bound structure of the E. coli multidrug resistance transporter MdfA
Cell Res., 25, 2015
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4YSB
 | | Crystal structure of ETHE1 from Myxococcus xanthus | | 分子名称: | FE (III) ION, Metallo-beta-lactamase family protein | | 著者 | Sattler, S.A, Wang, X, DeHan, P.J, Xun, L, Kang, C. | | 登録日 | 2015-03-17 | | 公開日 | 2015-06-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5015 Å) | | 主引用文献 | Characterizations of Two Bacterial Persulfide Dioxygenases of the Metallo-beta-lactamase Superfamily.
J.Biol.Chem., 290, 2015
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4YSK
 | | Crystal structure of apo-form SdoA from Pseudomonas putida | | 分子名称: | Beta-lactamase domain protein, FE (III) ION | | 著者 | Sattler, S.A, Wang, X, DeHan, P.J, Xun, L, Kang, C. | | 登録日 | 2015-03-17 | | 公開日 | 2015-06-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.466 Å) | | 主引用文献 | Characterizations of Two Bacterial Persulfide Dioxygenases of the Metallo-beta-lactamase Superfamily.
J.Biol.Chem., 290, 2015
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7VUX
 | | Complex structure of PD1 and 609A-Fab | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Huang, H, Zhu, Z, Zhao, J, Jiang, L, Yang, H, Deng, L, Meng, X, Ding, J, Yang, S, Zhao, L, Xu, W, Wang, X. | | 登録日 | 2021-11-04 | | 公開日 | 2021-11-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | A strategy for the efficient construction of anti-PD1-based bispecific antibodies with desired IgG-like properties.
Mabs, 14, 2022
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5ABJ
 | | Structure of Coxsackievirus A16 in complex with GPP3 | | 分子名称: | 1-[(3S)-5-[4-[(E)-ETHOXYIMINOMETHYL]PHENOXY]-3-METHYL-PENTYL]-3-PYRIDIN-4-YL-IMIDAZOLIDIN-2-ONE, CHLORIDE ION, SODIUM ION, ... | | 著者 | De Colibus, L, Wang, X, Tijsma, A, Neyts, J, Spyrou, J.A.B, Ren, J, Grimes, J.M, Puerstinger, G, Leyssen, P, Fry, E.E, Rao, Z, Stuart, D.I. | | 登録日 | 2015-08-06 | | 公開日 | 2015-09-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure Elucidation of Coxsackievirus A16 in Complex with Gpp3 Informs a Systematic Review of Highly Potent Capsid Binders to Enteroviruses.
Plos Pathog., 11, 2015
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