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PDB: 484 件

7E2H
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Cryo-EM structure of hDisp1NNN-3C-Cleavage
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1
著者Li, W, Wang, L, Gong, X.
登録日2021-02-05
公開日2021-12-08
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release.
Nat Commun, 12, 2021
7FAT
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Structure Determination of the RBD-NB1A7
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, nb_1A7
著者Geng, Y, Shi, Z.Z, Li, X.Y, Wang, L, Sun, Z.C, Zhang, H.W, Chen, X.C.
登録日2021-07-07
公開日2022-05-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural basis of nanobodies neutralizing SARS-CoV-2 variants
Structure, 30, 2022
7FAU
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Structure Determination of the NB1B11-RBD Complex
分子名称: NB_1B11, Spike protein S1, ZINC ION
著者Shi, Z.Z, Li, X.X, Wang, L, Sun, Z.C, Zhang, H.W, Chen, X.C, Cui, Q.Q, Qiao, H.R, Lan, Z.Y, Zhang, X.
登録日2021-07-07
公開日2022-06-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural basis of nanobodies neutralizing SARS-CoV-2 variants.
Structure, 30, 2022
7YLM
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Cryo-EM structure of 8-subunit Smc5/6 hinge region
分子名称: MMS21 isoform 1, SMC6 isoform 1, Structural maintenance of chromosomes protein 5
著者Qian, L, Jun, Z, Xiang, Z, Wang, Z, Tong, C, Duo, J, Zhenguo, C, Wang, L.
登録日2022-07-26
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (6.17 Å)
主引用文献Cryo-EM structure of 8-subunit Smc5/6 hinge region
To Be Published
3TY5
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Crystal Structure of C. thermocellum PNKP Ligase domain in complex with ATP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Polynucleotide 2',3'-cyclic phosphate phosphodiesterase / polynucleotide 5'-hydroxyl-kinase / polynucleotide 3'-phosphatase, ...
著者Smith, P, Wang, L, Shuman, S.
登録日2011-09-23
公開日2012-01-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The adenylyltransferase domain of bacterial Pnkp defines a unique RNA ligase family.
Proc.Natl.Acad.Sci.USA, 109, 2012
7XKC
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Crystal structure of Daucus Carrot hypoglycemic peptide (DCHP)
分子名称: DCHP, SULFATE ION
著者Guo, T, Ren, J.Q, Wang, L, Shi, Y.W, Feng, W.
登録日2022-04-19
公開日2022-05-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Characterization of a thermostable, protease-tolerant inhibitor of alpha-glycosidase from carrot: A potential oral additive for treatment of diabetes.
Int.J.Biol.Macromol., 209, 2022
7VFB
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the complex of SARS-CoV2 3cl and NB2B4
分子名称: 3C-like proteinase, nb2b4
著者Geng, Y, Sun, Z.C, Wang, L.
登録日2021-09-11
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An extended conformation of SARS-CoV-2 main protease reveals allosteric targets.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VFA
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the complex of SARS-CoV2 3CL and NB1A2
分子名称: 3C-like proteinase, NB1A2, SULFATE ION
著者Sun, Z.C, Wang, L, Geng, Y.
登録日2021-09-11
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献An extended conformation of SARS-CoV-2 main protease reveals allosteric targets.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VZB
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Cryo-EM structure of C22:0-CoA bound human very long-chain fatty acid ABC transporter ABCD1
分子名称: CHOLESTEROL HEMISUCCINATE, Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] docosanethioate
著者Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z.
登録日2021-11-15
公開日2022-05-18
最終更新日2022-06-22
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
Nat Commun, 13, 2022
7VWC
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Cryo-EM structure of human very long-chain fatty acid ABC transporter ABCD1
分子名称: Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1, [(2R)-3-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-2-oxidanyl-propyl] octadecanoate
著者Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z.
登録日2021-11-10
公開日2022-05-18
最終更新日2022-06-22
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
Nat Commun, 13, 2022
7VX8
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Cryo-EM structure of ATP-bound human very long-chain fatty acid ABC transporter ABCD1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1
著者Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z.
登録日2021-11-12
公開日2022-05-18
最終更新日2022-06-22
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
Nat Commun, 13, 2022
7XC6
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Photobacterium phosphoreum fatty acid reductase complex LuxC-LuxE
分子名称: Long-chain acyl-protein thioester reductase, LuxE
著者Tian, Q, Huo, Y, Wang, L.
登録日2022-03-23
公開日2022-04-20
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Cryo-EM structure of the fatty acid reductase LuxC-LuxE complex provides insights into bacterial bioluminescence.
J.Biol.Chem., 298, 2022
6O9O
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Crystal Structure of SMYD3 with Potent and Selective Isoxazole Amide Inhibitor 1
分子名称: 5-cyclopropyl-N-{1-[({trans-4-[(4,4,4-trifluorobutyl)amino]cyclohexyl}methyl)sulfonyl]piperidin-4-yl}-1,2-oxazole-3-carboxamide, GLYCEROL, Histone-lysine N-methyltransferase SMYD3, ...
著者Elkins, P.A, Wang, L.
登録日2019-03-14
公開日2020-03-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.586 Å)
主引用文献Discovery of Isoxazole Amides as Potent and Selective SMYD3 Inhibitors
To be published
7CYF
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Cryo-EM structure of bicarbonate transporter SbtA in complex with PII-like signaling protein SbtB from Synechocystis sp. PCC 6803
分子名称: ADENOSINE MONOPHOSPHATE, Membrane-associated protein slr1513, SODIUM ION, ...
著者Liu, X.Y, Jiang, Y.L, Wang, L, Hou, W.T, Chen, Y, Zhou, C.Z.
登録日2020-09-03
公開日2021-06-23
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structures of cyanobacterial bicarbonate transporter SbtA and its complex with PII-like SbtB.
Cell Discov, 7, 2021
7CYE
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Cryo-EM structure of sodium-dependent bicarbonate transporter SbtA from Synechocystis sp. PCC 6803
分子名称: Slr1512 protein
著者Liu, X.Y, Jiang, Y.L, Wang, L, Hou, W.T, Chen, Y, Zhou, C.Z.
登録日2020-09-03
公開日2021-06-23
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structures of cyanobacterial bicarbonate transporter SbtA and its complex with PII-like SbtB.
Cell Discov, 7, 2021
7DVQ
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BU of 7dvq by Molmil
Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ...
著者Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y.
登録日2021-01-14
公開日2021-03-31
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Structure of the activated human minor spliceosome.
Science, 371, 2021
7D1G
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Crystal structure of Glyceraldehyde-3-Phosphate Dehydrogenase GAPDH from Clostridium beijerinckii
分子名称: BETA-MERCAPTOETHANOL, Glyceraldehyde-3-phosphate dehydrogenase, MAGNESIUM ION
著者Chen, Y, Lan, J, Liu, W, Wang, L, Xu, Y.
登録日2020-09-14
公開日2021-03-17
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structure of Glyceraldehyde-3-Phosphate Dehydrogenase GAPDH from Clostridium beijerinckii
To Be Published
7DUO
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BU of 7duo by Molmil
Crystal structure of daratumumab fab and CD38 complex
分子名称: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Fab heavy chain, Fab light chain
著者Yu, X.J, Wang, L, Yu, C.F.
登録日2021-01-10
公開日2021-03-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystal structure of daratumumab fab and CD38 complex
To Be Published
7DUN
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BU of 7dun by Molmil
Crystal structure of Fab fragment of Daratumumab
分子名称: Fab heavy chain, Fab light chain
著者Yu, X.J, Wang, L, Yu, C.F.
登録日2021-01-10
公開日2021-03-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.607 Å)
主引用文献Crystal structure of Fab fragment of Daratumumab
To Be Published
7CQI
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BU of 7cqi by Molmil
Cryo-EM structure of the substrate-bound SPT-ORMDL3 complex
分子名称: ORM1-like protein 3, Serine palmitoyltransferase 1, Serine palmitoyltransferase 2, ...
著者Li, S.S, Xie, T, Wang, L, Gong, X.
登録日2020-08-11
公開日2021-02-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
7CQK
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Cryo-EM structure of the substrate-bound SPT-ORMDL3 complex
分子名称: ORM1-like protein 3, Serine palmitoyltransferase 1, Serine palmitoyltransferase 2, ...
著者Li, S.S, Xie, T, Wang, L, Gong, X.
登録日2020-08-11
公開日2021-02-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
7EXX
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BU of 7exx by Molmil
The structure of DndG
分子名称: DNA phosphorothioation-dependent restriction protein DptG, SODIUM ION
著者Wu, D, Wang, L.
登録日2021-05-28
公開日2022-06-01
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The functional coupling between restriction and DNA phosphorothioate modification systems underlying the DndFGH restriction complex
Nat Catal, 2022
7FJG
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Crystal structure of butanol dehydrogenase A (YqdH) in complex with partial NADH from Fusobacterium nucleatum
分子名称: ADENOSINE-5'-DIPHOSPHATE, FE (III) ION, NADH-dependent butanol dehydrogenase A
著者Bai, X, Lan, J, Wang, L, Bu, T, Xu, Y.
登録日2021-08-03
公開日2022-06-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Crystal structure of butanol dehydrogenase A (YqdH) in complex with partial NADH from Fusobacterium nucleatum
To Be Published
7FDV
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Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 1, CHOLESTEROL, ...
著者Xu, D, Li, Y.Y, Yang, F.R, Sun, C.R, Pan, J.H, Wang, L, Chen, Z.P, Fang, S.C, Yao, X.B, Hou, W.T, Zhou, C.Z, Chen, Y.
登録日2021-07-18
公開日2022-06-22
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structure and transport mechanism of the human cholesterol transporter ABCG1.
Cell Rep, 38, 2022
7ENN
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The structure of ALC1 bound to the nucleosome
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromodomain-helicase-DNA-binding protein 1-like, ...
著者Chen, Z.C, Chen, K.J, Wang, L.
登録日2021-04-18
公開日2021-07-14
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome.
Nat Commun, 12, 2021

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