6O9O

Crystal Structure of SMYD3 with Potent and Selective Isoxazole Amide Inhibitor 1

Summary for 6O9O

• Entry DOI: 10.2210/pdb6o9o/pdb
• Related: 6NTQ
• Descriptor: Histone-lysine N-methyltransferase SMYD3, ZINC ION, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: histone, mynd, set, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 50968.66

Authors

Elkins, P.A.,Wang, L. (deposition date: 2019-03-14, release date: 2020-03-18, Last modification date: 2024-03-13)

• Primary citation: Su, D.-S.,Elkins, P.A.; Discovery of Isoxazole Amides as Potent and Selective SMYD3 Inhibitors; To be published,

Experimental method

X-RAY DIFFRACTION (1.586 Å)