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PDB: 8 results

6V0L
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BU of 6v0l by Molmil
PDGFR-b Promoter Forms a G-Vacancy Quadruplex that Can be Complemented by dGMP: Molecular Structure and Recognition of Guanine Derivatives and Metabolites
Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, DNA (5'-D(*(3D1)P*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*AP*CP*A)-3')
Authors:Wang, K.B, Dickerhoff, J, Wu, G, Yang, D.
Deposit date:2019-11-18
Release date:2020-03-11
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:PDGFR-beta Promoter Forms a Vacancy G-Quadruplex that Can Be Filled in by dGMP: Solution Structure and Molecular Recognition of Guanine Metabolites and Drugs.
J.Am.Chem.Soc., 142, 2020
7MSV
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BU of 7msv by Molmil
Solution Structure of Berberine Bound to a dGMP Fill-in G-Quadruplex in the PDGFR-b Promoter
Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, BERBERINE, DNA (5'-D(*AP*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*AP*CP*A)-3')
Authors:Wang, K.B, Dickerhoff, J, Yang, D.
Deposit date:2021-05-12
Release date:2021-10-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution Structure of Ternary Complex of Berberine Bound to a dGMP-Fill-In Vacancy G-Quadruplex Formed in the PDGFR-beta Promoter.
J.Am.Chem.Soc., 143, 2021
7X8M
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NMR Solution Structure of the 2:1 Berberine-KRAS-G4 Complex
Descriptor: BERBERINE, DNA (24-MER)
Authors:Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y.
Deposit date:2022-03-14
Release date:2022-09-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.
Nat Commun, 13, 2022
7X8O
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NMR Solution Structure of the 2:1 Coptisine-KRAS-G4 Complex
Descriptor: 6,7-dihydro[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquino[3,2-a]isoquinolin-5-ium, DNA (24-MER)
Authors:Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y.
Deposit date:2022-03-14
Release date:2022-09-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.
Nat Commun, 13, 2022
7X8N
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NMR Solution Structure of the Wild-type Bulge-containing KRAS-G4
Descriptor: DNA (24-mer)
Authors:Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y.
Deposit date:2022-03-14
Release date:2022-09-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.
Nat Commun, 13, 2022
7WGW
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BU of 7wgw by Molmil
NMR Solution Structure of a cGMP Fill-in Vacancy G-quadruplex Formed in the Oxidized BLM Gene Promoter
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, DNA (20-MER)
Authors:Wang, K.B, Liu, Y, Li, Y, Li, J, Dickerhoff, J, Yang, M.H, Yang, D, Kong, L.Y.
Deposit date:2021-12-29
Release date:2022-05-18
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter.
J.Am.Chem.Soc., 144, 2022
8JFQ
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Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-back Loop
Descriptor: 26mer-DNA
Authors:Liu, Y, Li, J, Zhang, Y, Wang, Y, Chen, J, Bian, Y, Xia, Y, Yang, M.H, Zheng, K, Wang, K.B, Kong, L.Y.
Deposit date:2023-05-18
Release date:2023-08-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-Back Loop.
J.Am.Chem.Soc., 145, 2023
8WA4
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Solution structure of free ATF4 promoter G-quadruplex
Descriptor: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, DNA G-quadruplex, THYMIDINE
Authors:Liu, Y.S, Wang, K.B.
Deposit date:2023-09-07
Release date:2024-09-11
Method:SOLUTION NMR
Cite:Stabilizing ATF4 promoter G-quadruplex overcomes the resistance of glutamine-restricted cancer therapy
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数据于2024-09-18公开中

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