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8WA4

Solution structure of free ATF4 promoter G-quadruplex

Summary for 8WA4
Entry DOI10.2210/pdb8wa4/pdb
DescriptorDNA G-quadruplex, THYMIDINE, 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE (3 entities in total)
Functional Keywordsatf4 promoter, g-quadruplex, nmr solution structure, glutamine-restricted cancer, dna
Biological sourceHomo sapiens
Total number of polymer chains1
Total formula weight6976.59
Authors
Liu, Y.S.,Wang, K.B. (deposition date: 2023-09-07, release date: 2024-09-11)
Primary citationXiao, C.M.,Li, Y.P.,Liu, Y.S.,Dong, R.F.,He, X.Y.,Lin, Q.,Zang, X.,Wang, K.B.,Xia, Y.Z.,Kong, L.Y.
Stabilizing ATF4 promoter G-quadruplex overcomes the resistance of glutamine-restricted cancer therapy
To Be Published,
Experimental method
SOLUTION NMR
Structure validation

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