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PDB: 1203 件
8J23
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BU of 8j23 by Molmil
Cryo-EM structure of FFAR2 complex in apo state
分子名称: Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Tai, L, Li, F, Sun, X, Tang, W, Wang, J.
登録日2023-04-14
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular recognition and activation mechanism of short chain fatty acid receptors FFAR2 and FFAR3
To Be Published
2ERF
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BU of 2erf by Molmil
Crystal Structure of the Thrombospondin-1 N-terminal Domain at 1.45A Resolution
分子名称: Thrombospondin-1
著者Tan, K, Wang, J, Lawler, J.
登録日2005-10-24
公開日2006-01-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The structures of the thrombospondin-1 N-terminal domain and its complex with a synthetic pentameric heparin.
Structure, 14, 2006
1R5H
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BU of 1r5h by Molmil
Crystal Structure of MetAP2 complexed with A320282
分子名称: MANGANESE (II) ION, Methionine aminopeptidase 2, N'-(2S,3R)-3-AMINO-4-CYCLOHEXYL-2-HYDROXY-BUTANO-N-(4-METHYLPHENYL)HYDRAZIDE
著者Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R.
登録日2003-10-10
公開日2004-10-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg.Med.Chem.Lett., 14, 2004
1R58
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BU of 1r58 by Molmil
Crystal Structure of MetAP2 complexed with A357300
分子名称: MANGANESE (II) ION, Methionine aminopeptidase 2, N'-((2S,3R)-3-AMINO-2-HYDROXY-5-(ISOPROPYLSULFANYL)PENTANOYL)-N-3-CHLOROBENZOYL HYDRAZIDE
著者Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Ericken, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R.
登録日2003-10-09
公開日2004-10-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg.Med.Chem.Lett., 14, 2004
1OZE
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BU of 1oze by Molmil
Crystal Structures of the Ferric, Ferrous, and Ferrous-NO Forms of the Asp140Ala Mutant of Human Heme Oxygenase-1:Catalytic Implications
分子名称: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
著者Lad, L, Wang, J, Li, H, Friedman, J, Ortiz de Montellano, P.R, Poulos, T.L.
登録日2003-04-08
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications
J.Mol.Biol., 330, 2003
1OYL
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BU of 1oyl by Molmil
Crystal Structures of the Ferric, Ferrous, and Ferrous-NO Forms of the Asp140Ala Mutant of Human Heme Oxygenase-1: Catalytic Implications
分子名称: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
著者Lad, L, Wang, J, Li, H, Friedman, J, Ortiz de Montellano, P.R, Poulos, T.L.
登録日2003-04-05
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications
J.Mol.Biol., 330, 2003
1W63
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BU of 1w63 by Molmil
AP1 clathrin adaptor core
分子名称: ADAPTER-RELATED PROTEIN COMPLEX 1 BETA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 SIGMA 1A SUBUNIT, ...
著者Heldwein, E, Macia, E, Wang, J, Yin, H.L, Kirchhausen, T, Harrison, S.C.
登録日2004-08-12
公開日2004-09-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal Structure of the Clathrin Adaptor Protein 1 Core
Proc.Natl.Acad.Sci.USA, 101, 2004
4N77
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BU of 4n77 by Molmil
Crystal structure of Cas protein
分子名称: Uncharacterized protein
著者Tian, W, Sheng, G, Zhao, H, Wang, J, Wang, Y.
登録日2013-10-15
公開日2014-10-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Crystal strucute studies of CasD
To be Published
1I5T
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BU of 1i5t by Molmil
SOLUTION STRUCTURE OF CYANOFERRICYTOCHROME C
分子名称: CYANIDE ION, CYTOCHROME C, HEME C
著者Yao, Y, Qian, C, Ye, K, Wang, J, Tang, W.
登録日2001-02-28
公開日2001-03-21
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of cyanoferricytochrome c: ligand-controlled conformational flexibility and electronic structure of the heme moiety.
J.Biol.Inorg.Chem., 7, 2002
5UZ0
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BU of 5uz0 by Molmil
Crystal structure of AICARFT bound to an antifolate
分子名称: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Bifunctional purine biosynthesis protein PURH, MAGNESIUM ION, ...
著者Atwell, S, Wang, Y, Fales, K.R, Clawson, D, Wang, J.
登録日2017-02-24
公開日2018-01-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model.
J. Med. Chem., 60, 2017
7YIM
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BU of 7yim by Molmil
Cryo-EM structure of human Alpha-fetoprotein
分子名称: Alpha-fetoprotein
著者Liu, N, Liu, K, Wu, C, Liu, Z, Li, M, Wang, J, Wang, H.W.
登録日2022-07-17
公開日2023-01-18
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Uniform thin ice on ultraflat graphene for high-resolution cryo-EM.
Nat.Methods, 20, 2023
7KX5
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BU of 7kx5 by Molmil
Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with noncovalent inhibitor Jun8-76-3A
分子名称: 3C-like proteinase, GLYCEROL, N-([1,1'-biphenyl]-4-yl)-N-[(1R)-2-oxo-2-{[(1S)-1-phenylethyl]amino}-1-(pyridin-3-yl)ethyl]furan-2-carboxamide
著者Sacco, M, Wang, J, Chen, Y.
登録日2020-12-03
公開日2020-12-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity.
J.Am.Chem.Soc., 143, 2021
1FFY
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BU of 1ffy by Molmil
INSIGHTS INTO EDITING FROM AN ILE-TRNA SYNTHETASE STRUCTURE WITH TRNA(ILE) AND MUPIROCIN
分子名称: ISOLEUCYL-TRNA, ISOLEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, ...
著者Silvian, L.F, Wang, J, Steitz, T.A.
登録日2000-07-26
公開日2000-08-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin.
Science, 285, 1999
1M4B
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BU of 1m4b by Molmil
Crystal Structure of Human Interleukin-2 K43C Covalently Modified at C43 with 2-[2-(2-Cyclohexyl-2-guanidino-acetylamino)-acetylamino]-N-(3-mercapto-propyl)-propionamide
分子名称: 2-[2-(2-CYCLOHEXYL-2-GUANIDINO-ACETYLAMINO)-ACETYLAMINO]-N-(3-MERCAPTO-PROPYL)-PROPIONAMIDE, interleukin-2
著者Arkin, M.A, Randal, M, DeLano, W.L, Hyde, J, Luong, T.N, Oslob, J.D, Raphael, D.R, Taylor, L, Wang, J, McDowell, R.S, Wells, J.A, Braisted, A.C.
登録日2002-07-02
公開日2002-07-31
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Binding of small molecules to an adaptive protein-protein interface
Proc.Natl.Acad.Sci.USA, 100, 2003
1R5G
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BU of 1r5g by Molmil
Crystal Structure of MetAP2 complexed with A311263
分子名称: (2S,3R)-3-AMINO-2-HYDROXY-5-(ETHYLSULFANYL)PENTANOYL-((S)-(-)-(1-NAPHTHYL)ETHYL)AMIDE, MANGANESE (II) ION, Methionine aminopeptidase 2
著者Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R.
登録日2003-10-10
公開日2004-10-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg.Med.Chem.Lett., 14, 2004
3IU3
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BU of 3iu3 by Molmil
Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain
分子名称: Heavy chain of Fab fragment of Basiliximab, Interleukin-2 receptor alpha chain, Light chain of Fab fragment of Basiliximab, ...
著者Du, J, Yang, H, Wang, J, Ding, J.
登録日2009-08-29
公開日2010-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab
J.Immunol., 184, 2010
5ZM8
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BU of 5zm8 by Molmil
Crystal structure of ORP2-ORD in complex with PI(4,5)P2
分子名称: Oxysterol-binding protein-related protein 2, [(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{S},5~{S},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl] icosa-5,8,11,14-tetraenoate
著者Wang, H, Dong, J.Q, Wang, J, Wu, J.W.
登録日2018-04-01
公開日2019-01-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P2).
Mol. Cell, 73, 2019
1M48
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BU of 1m48 by Molmil
Crystal Structure of Human IL-2 Complexed with (R)-N-[2-[1-(Aminoiminomethyl)-3-piperidinyl]-1-oxoethyl]-4-(phenylethynyl)-L-phenylalanine methyl ester
分子名称: 2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3-(4-PHENYLETHYNYL-PHENYL)-PROPIONIC ACID METHYL ESTER, interleukin-2
著者Arkin, M.A, Randal, M, DeLano, W.L, Hyde, J, Luong, T.N, Oslob, J.D, Raphael, D.R, Taylor, L, Wang, J, McDowell, R.S, Wells, J.A, Braisted, A.C.
登録日2002-07-02
公開日2002-07-31
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Binding of small molecules to an adaptive protein-protein interface
Proc.Natl.Acad.Sci.USA, 100, 2003
2BAZ
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BU of 2baz by Molmil
Structure of YosS, a putative dUTPase from Bacillus subtilis
分子名称: hypothetical protein BSU20020
著者Liang, Y.-H, Wang, J, Su, X.-D.
登録日2005-10-16
公開日2006-10-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of YosS, a putative dUTPase from Bacillus subtilis
To be Published
7YOJ
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BU of 7yoj by Molmil
Structure of CasPi with guide RNA and target DNA
分子名称: CasPi, DNA (30-MER), DNA (5'-D(P*CP*GP*GP*GP*AP*TP*GP*CP*CP*CP*AP*G)-3'), ...
著者Li, C.P, Wang, J, Liu, J.J.
登録日2022-08-01
公開日2023-02-15
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献The compact Cas pi (Cas12l) 'bracelet' provides a unique structural platform for DNA manipulation.
Cell Res., 33, 2023
1NMI
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BU of 1nmi by Molmil
Solution structure of the imidazole complex of iso-1 cytochrome c
分子名称: Cytochrome c, iso-1, HEME C, ...
著者Yao, Y, Tong, Y, Liu, G, Wang, J, Zheng, J, Tang, W.
登録日2003-01-10
公開日2003-02-04
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the imidazole complex of iso-1 cytochrome c
To be Published
1OZR
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BU of 1ozr by Molmil
Crystal Structures of the Ferric, Ferrous and Ferrous-NO Forms of the Asp140Ala Mutant of Human Heme Oxygenase-1: Catalytic Implications
分子名称: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
著者Lad, L, Wang, J, Li, H, Friedman, J, Ortiz de Montellano, P.R, Poulos, T.L.
登録日2003-04-09
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications
J.Mol.Biol., 330, 2003
2ES3
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BU of 2es3 by Molmil
Crystal Structure of Thrombospondin-1 N-terminal Domain in P1 Form at 1.85A Resolution
分子名称: Thrombospondin-1
著者Tan, K, Wang, J, Lawler, J.
登録日2005-10-25
公開日2006-10-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Heparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal Domain.
J.Biol.Chem., 283, 2008
1V6P
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BU of 1v6p by Molmil
Crystal structure of Cobrotoxin
分子名称: CHLORIDE ION, COPPER (II) ION, Cobrotoxin, ...
著者Lou, X, Tu, X, Wang, J, Teng, M, Niu, L, Liu, Q, Huang, Q, Hao, Q.
登録日2003-12-03
公開日2004-12-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (0.87 Å)
主引用文献The atomic resolution crystal structure of atratoxin determined by single wavelength anomalous diffraction phasing
J.Biol.Chem., 279, 2004
1OZL
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BU of 1ozl by Molmil
Crystal Structures of the Ferric, Ferrous, and Ferrous-NO Forms of the Asp140Ala Mutant of Human Heme Oxygenase-1: Catalytic Implications
分子名称: Heme oxygenase 1, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE
著者Lad, L, Wang, J, Li, H, Friedman, J, Ortiz de Montellano, P.R, Poulos, T.L.
登録日2003-04-09
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications
J.Mol.Biol., 330, 2003

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