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PDB: 1197 件

7UW6
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The co-crystal structure of low molecular weight protein tyrosine phosphatase (LMW-PTP) with a small molecule inhibitor SPAA-2
分子名称: 2-[(1,3-benzothiazol-2-yl)amino]-2-oxoethane-1-sulfonic acid, Low molecular weight phosphotyrosine protein phosphatase
著者Wang, J, Zhang, Z.Y.
登録日2022-05-02
公開日2022-10-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors.
J.Med.Chem., 65, 2022
8HUW
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Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with S217622
分子名称: 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione
著者Wang, J, Zhang, J, Li, J.
登録日2022-12-24
公開日2023-06-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for the inhibition of coronaviral main proteases by ensitrelvir.
Structure, 31, 2023
7YVT
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S-formylglutathione hydrolase from Variovorax sp. PAMC 28711
分子名称: S-formylglutathione hydrolase
著者Hwang, J, Do, H, Lee, J.H.
登録日2022-08-19
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structural basis for the substrate specificity of an S-formylglutathione hydrolase derived from Variovorax sp. PAMC 28711.
Biochem.Biophys.Res.Commun., 629, 2022
8JUO
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Crystal structure of aspartate semialdehyde dehydrogenase from Porphyromonas gingivalis
分子名称: Aspartate-semialdehyde dehydrogenase
著者Hwang, J, Do, H, Lee, J.H.
登録日2023-06-27
公開日2024-06-05
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal Structure of Aspartate Semialdehyde Dehydrogenase from Porphyromonas gingivalis.
Crystals, 13, 2023
8JUS
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Crystal structure of aspartate semialdehyde dehydrogenase from Porphyromonas gingivalis complexed with 2',5'adenosine diphosphate
分子名称: ADENOSINE-2'-5'-DIPHOSPHATE, Aspartate-semialdehyde dehydrogenase
著者Hwang, J, Do, H, Lee, J.H.
登録日2023-06-27
公開日2024-06-05
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal Structure of Aspartate Semialdehyde Dehydrogenase from Porphyromonas gingivalis.
Crystals, 13, 2023
5HWT
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Crystal structure of apo-PAS1
分子名称: Sensor histidine kinase TodS
著者Hwang, J, Koh, S.
登録日2016-01-29
公開日2016-03-02
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular Insights into Toluene Sensing in the TodS/TodT Signal Transduction System.
J. Biol. Chem., 291, 2016
5HWW
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Crystal structure of PAS1 complexed with 1,2,4-TMB
分子名称: 1,2,4-trimethylbenzene, Sensor histidine kinase TodS
著者Hwang, J, Koh, S.
登録日2016-01-29
公開日2016-03-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular Insights into Toluene Sensing in the TodS/TodT Signal Transduction System.
J. Biol. Chem., 291, 2016
5HWV
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Crystal structure of PAS1 complexed with toluene
分子名称: Sensor histidine kinase TodS, TOLUENE
著者Hwang, J, Koh, S.
登録日2016-01-29
公開日2016-03-02
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Molecular Insights into Toluene Sensing in the TodS/TodT Signal Transduction System.
J. Biol. Chem., 291, 2016
4GFX
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Crystal structure of the N-terminal domain of TXNIP
分子名称: GLYCEROL, Thioredoxin-interacting protein
著者Hwang, J, Kim, M.H.
登録日2012-08-04
公開日2014-02-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein.
Nat Commun, 5, 2014
2XMQ
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Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor
分子名称: ACETATE ION, PROTEIN NDRG2
著者Hwang, J, Kim, Y, Lee, H, Kim, M.H.
登録日2010-07-29
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor.
J.Biol.Chem., 286, 2011
8HM5
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Epoxide hydrolase from Caballeronia sordidicola PAMC 26510
分子名称: Epoxide hydrolase
著者Hwang, J, Lee, M.J, Do, H, Lee, J.H.
登録日2022-12-02
公開日2023-12-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structural insights into the distinct substrate preferences of two bacterial epoxide hydrolases.
Int.J.Biol.Macromol., 264, 2024
8ILJ
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S-formylglutathione hydrolase (BuSFGH) from Burkholderiaceae sp.
分子名称: S-formylglutathione hydrolase
著者Hwang, J, Lee, J.H, Do, H.
登録日2023-03-03
公開日2024-01-10
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal structure and functional characterization of an S-formylglutathione hydrolase (BuSFGH) from Burkholderiaceae sp.
Crystals, 13, 2023
6LVO
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Enoyl-CoA isomerase (BoECI) from Bosea sp. PAMC 26642
分子名称: Enoyl-CoA hydratase
著者Hwang, J, Jung, C, Lee, C.W, Lee, J.H.
登録日2020-02-04
公開日2020-04-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural and sequence comparisons of bacterial enoyl-CoA isomerase and enoyl-CoA hydratase.
J.Microbiol, 58, 2020
2XMS
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BU of 2xms by Molmil
Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor
分子名称: CHLORIDE ION, IMIDAZOLE, PROTEIN NDRG2
著者Hwang, J, Kim, Y, Lee, H, Kim, M.H.
登録日2010-07-29
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor.
J.Biol.Chem., 286, 2011
2XMR
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Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor
分子名称: ACETATE ION, CALCIUM ION, GLYCEROL, ...
著者Hwang, J, Kim, Y, Lee, H, Kim, M.H.
登録日2010-07-29
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor.
J.Biol.Chem., 286, 2011
8HEA
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BU of 8hea by Molmil
Esterase2 (EaEst2) from Exiguobacterium antarcticum
分子名称: Thermostable carboxylesterase Est30
著者Hwang, J, Lee, J.H.
登録日2022-11-08
公開日2023-09-20
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural and Biochemical Insights into Bis(2-hydroxyethyl) Terephthalate Degrading Carboxylesterase Isolated from Psychrotrophic Bacterium Exiguobacterium antarcticum.
Int J Mol Sci, 24, 2023
4LL1
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The structure of the TRX and TXNIP complex
分子名称: Thioredoxin, Thioredoxin-interacting protein
著者Hwang, J, Kim, M.H.
登録日2013-07-09
公開日2014-02-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
Nat Commun, 5, 2014
4LL4
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BU of 4ll4 by Molmil
The structure of the TRX and TXNIP complex
分子名称: Thioredoxin, Thioredoxin-interacting protein
著者Hwang, J, Kim, M.H.
登録日2013-07-09
公開日2014-02-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
Nat Commun, 5, 2014
4IVN
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BU of 4ivn by Molmil
The Vibrio vulnificus NanR protein complexed with ManNAc-6P
分子名称: 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-mannopyranose, Transcriptional regulator
著者Hwang, J, Kim, M.H.
登録日2013-01-23
公開日2013-07-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the regulation of sialic acid catabolism by the Vibrio vulnificus transcriptional repressor NanR
Proc.Natl.Acad.Sci.USA, 110, 2013
5DQY
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A fully oxidized human thioredoxin
分子名称: BENZOIC ACID, CHLORIDE ION, GLYCEROL, ...
著者Hwang, J.
登録日2015-09-15
公開日2015-12-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of fully oxidized human thioredoxin.
Biochem.Biophys.Res.Commun., 467, 2015
7XRH
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BU of 7xrh by Molmil
Feruloyl esterase from Lactobacillus acidophilus
分子名称: Cinnamoyl esterase
著者Hwang, J, Lee, C.W, Lee, J.H, Do, H.
登録日2022-05-10
公開日2023-05-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Feruloyl Esterase ( La Fae) from Lactobacillus acidophilus : Structural Insights and Functional Characterization for Application in Ferulic Acid Production.
Int J Mol Sci, 24, 2023
5XLN
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BU of 5xln by Molmil
Crystal structure of the TRS_UNE-T and 4EHP complex
分子名称: Eukaryotic translation initiation factor 4E type 2, Threonine--tRNA ligase, cytoplasmic
著者Hwang, J, Nguyen, L.T, Kim, M.H.
登録日2017-05-11
公開日2018-11-21
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A threonyl-tRNA synthetase-mediated translation initiation machinery.
Nat Commun, 10, 2019
6H1X
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Receptor-binding domain of Proteus mirabilis Uroepithelial Cell Adhesin UcaD21-211
分子名称: COBALT (II) ION, Putative fimbrial adhesin
著者Wangshu, J, Knight, S.D.
登録日2018-07-12
公開日2018-11-07
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of two fimbrial adhesins, AtfE and UcaD, from the uropathogen Proteus mirabilis.
Acta Crystallogr D Struct Biol, 74, 2018
8WFC
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N5, N10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase
分子名称: Bifunctional protein FolD
著者Hwang, J, Lee, J.H, Do, H.
登録日2023-09-19
公開日2024-08-07
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure and Sequence Analysis of N5, N10-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase Enzyme from Porphyromonas gingivalis
Crystals, 13, 2023
6H1Q
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Proteus mirabilis Ambient Temperature Fimbriae adhesin AtfE
分子名称: Fimbrial adhesin, GLYCEROL, PHOSPHATE ION
著者Wangshu, J, Knight, S.D.
登録日2018-07-12
公開日2018-11-07
最終更新日2018-11-14
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structures of two fimbrial adhesins, AtfE and UcaD, from the uropathogen Proteus mirabilis.
Acta Crystallogr D Struct Biol, 74, 2018

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件を2024-08-21に公開中

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