7CSI
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![BU of 7csi by Molmil](/molmil-images/mine/7csi) | Aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis-Complex with Coenzyme A and Sisomicin | Descriptor: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, Aminoglycoside 2'-N-acetyltransferase, COENZYME A | Authors: | Jeong, C.S, Hwang, J, Do, H, Lee, J.H. | Deposit date: | 2020-08-14 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis. Sci Rep, 10, 2020
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7CSJ
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![BU of 7csj by Molmil](/molmil-images/mine/7csj) | Aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis-Complex with Coenzyme A and Gentamicin | Descriptor: | Aminoglycoside 2'-N-acetyltransferase, COENZYME A, gentamicin C1 | Authors: | Jeong, C.S, Hwang, J, Do, H, Lee, J.H. | Deposit date: | 2020-08-14 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.168 Å) | Cite: | Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis. Sci Rep, 10, 2020
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7CRM
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![BU of 7crm by Molmil](/molmil-images/mine/7crm) | Aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis-APO Structure | Descriptor: | 1,2-ETHANEDIOL, Aminoglycoside 2'-N-acetyltransferase | Authors: | Jeong, C.S, Hwang, J, Do, H, Lee, J.H. | Deposit date: | 2020-08-13 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.487 Å) | Cite: | Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis. Sci Rep, 10, 2020
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7CS0
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![BU of 7cs0 by Molmil](/molmil-images/mine/7cs0) | Aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis-Complex with Coenzyme A and Paromomycin | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Aminoglycoside 2'-N-acetyltransferase, ... | Authors: | Jeong, C.S, Hwang, J, Do, H, Lee, J.H. | Deposit date: | 2020-08-14 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis. Sci Rep, 10, 2020
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2XXN
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![BU of 2xxn by Molmil](/molmil-images/mine/2xxn) | Structure of the vIRF4-HAUSP TRAF domain complex | Descriptor: | K10, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 | Authors: | Choi, W.C, Hwang, J, Kim, M.H. | Deposit date: | 2010-11-11 | Release date: | 2011-11-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Bilateral Inhibition of Hausp Deubiquitinase by a Viral Interferon Regulatory Factor Protein Nat.Struct.Mol.Biol., 18, 2011
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6II2
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![BU of 6ii2 by Molmil](/molmil-images/mine/6ii2) | Crystal structure of alpha-beta hydrolase (ABH) and Makes Caterpillars Floppy (MCF)-Like effectors of Vibrio vulnificus MO6-24/O | Descriptor: | Putative RTX-toxin | Authors: | Lee, Y, Kim, B.S, Choi, S, Lee, E.Y, Park, S, Hwang, J, Kwon, Y, Hyung, J, Lee, C, Eom, S.H, Kim, M.H. | Deposit date: | 2018-10-03 | Release date: | 2019-08-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Makes caterpillars floppy-like effector-containing MARTX toxins require host ADP-ribosylation factor (ARF) proteins for systemic pathogenicity. Proc.Natl.Acad.Sci.USA, 116, 2019
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6II0
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![BU of 6ii0 by Molmil](/molmil-images/mine/6ii0) | Crystal structure of the Makes Caterpillars Floppy (MCF)-Like effector of Vibrio vulnificus MO6-24/O | Descriptor: | GLYCEROL, Putative RTX-toxin | Authors: | Lee, Y, Kim, B.S, Choi, S, Lee, E.Y, Park, S, Hwang, J, Kwon, Y, Hyun, J, Lee, C, Eom, S.H, Kim, M.H. | Deposit date: | 2018-10-03 | Release date: | 2019-08-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Makes caterpillars floppy-like effector-containing MARTX toxins require host ADP-ribosylation factor (ARF) proteins for systemic pathogenicity. Proc.Natl.Acad.Sci.USA, 116, 2019
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6II6
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![BU of 6ii6 by Molmil](/molmil-images/mine/6ii6) | Crystal structure of the Makes Caterpillars Floppy (MCF)-Like effector of Vibrio vulnificus MO6-24/O in complex with a human ADP-ribosylation factor 3 (ARF3) | Descriptor: | ADP-ribosylation factor 3, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Lee, Y, Kim, B.S, Choi, S, Lee, E.Y, Park, S, Hwang, J, Kwon, Y, Hyun, J, Lee, C, Eom, S.H, Kim, M.H. | Deposit date: | 2018-10-03 | Release date: | 2019-08-07 | Last modified: | 2020-02-19 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Makes caterpillars floppy-like effector-containing MARTX toxins require host ADP-ribosylation factor (ARF) proteins for systemic pathogenicity. Proc.Natl.Acad.Sci.USA, 116, 2019
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6IMP
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![BU of 6imp by Molmil](/molmil-images/mine/6imp) | |
6A7H
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![BU of 6a7h by Molmil](/molmil-images/mine/6a7h) | Bacterial protein toxins | Descriptor: | RTX toxin, SULFATE ION | Authors: | Kim, M.H, Hwang, J, Jang, S.Y. | Deposit date: | 2018-07-03 | Release date: | 2018-10-10 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structural basis of inactivation of Ras and Rap1 small GTPases by Ras/Rap1-specific endopeptidase from the sepsis-causing pathogenVibrio vulnificus J. Biol. Chem., 293, 2018
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6A8J
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![BU of 6a8j by Molmil](/molmil-images/mine/6a8j) | Crystal structure of bacterial protein toxins | Descriptor: | GLYCEROL, RTX toxin, SULFATE ION | Authors: | Kim, M.H, Hwang, J, Jang, S.Y. | Deposit date: | 2018-07-09 | Release date: | 2018-10-10 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.711 Å) | Cite: | Structural basis of inactivation of Ras and Rap1 small GTPases by Ras/Rap1-specific endopeptidase from the sepsis-causing pathogenVibrio vulnificus J. Biol. Chem., 293, 2018
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6J10
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![BU of 6j10 by Molmil](/molmil-images/mine/6j10) | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly | Descriptor: | 6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one, Capsid protein | Authors: | Park, S, Jin, M.S, Cho, Y, Kang, J, Kim, S, Park, M, Park, H, Kim, J, Park, S, Hwang, J, Kim, Y, Kim, Y.J. | Deposit date: | 2018-12-27 | Release date: | 2019-04-17 | Last modified: | 2019-05-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly. Nat Commun, 10, 2019
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8HGU
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![BU of 8hgu by Molmil](/molmil-images/mine/8hgu) | |
3Q2J
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![BU of 3q2j by Molmil](/molmil-images/mine/3q2j) | Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa Protein Kinase Inhibitor CKI-7 Complex | Descriptor: | Aminoglycoside 3'-phosphotransferase, CALCIUM ION, N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE | Authors: | Fong, D.H, Xiong, B, Hwang, J, Berghuis, A.M. | Deposit date: | 2010-12-20 | Release date: | 2011-05-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1501 Å) | Cite: | Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor. Plos One, 6, 2011
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1MKY
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![BU of 1mky by Molmil](/molmil-images/mine/1mky) | Structural Analysis of the Domain Interactions in Der, a Switch Protein Containing Two GTPase Domains | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, Probable GTP-binding protein engA | Authors: | Robinson, V.L, Hwang, J, Fox, E, Inouye, M, Stock, A.M. | Deposit date: | 2002-08-29 | Release date: | 2003-01-14 | Last modified: | 2015-02-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Domain Arrangement of Der, a Switch Protein Containing Two GTPase Domains Structure, 10, 2002
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3Q2M
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![BU of 3q2m by Molmil](/molmil-images/mine/3q2m) | Crystal Structure of Spectinomycin Phosphotransferase, APH(9)-Ia, Protein Kinase Inhibitor CKI-7 Complex | Descriptor: | N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE, NICKEL (II) ION, Spectinomycin phosphotransferase | Authors: | Berghuis, A.M, Fong, D.H, Xiong, B, Hwang, J. | Deposit date: | 2010-12-20 | Release date: | 2011-05-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor. Plos One, 6, 2011
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5X3R
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![BU of 5x3r by Molmil](/molmil-images/mine/5x3r) | Crystal structure of the SmcR complexed with QStatin | Descriptor: | 1-(5-bromanylthiophen-2-yl)sulfonylpyrazole, LuxR family transcriptional regulator, SULFATE ION | Authors: | Jang, S.Y, Hwang, J, Kim, M.H. | Deposit date: | 2017-02-07 | Release date: | 2018-01-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | QStatin, a Selective Inhibitor of Quorum Sensing inVibrioSpecies MBio, 9, 2018
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3I0O
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![BU of 3i0o by Molmil](/molmil-images/mine/3i0o) | Crystal Structure of Spectinomycin Phosphotransferase, APH(9)-Ia, in complex with ADP and Spectinomcyin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NICKEL (II) ION, ... | Authors: | Fong, D.H, Lemke, C.T, Hwang, J, Xiong, B, Berghuis, A.M. | Deposit date: | 2009-06-25 | Release date: | 2010-01-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the antibiotic resistance factor spectinomycin phosphotransferase from Legionella pneumophila. J.Biol.Chem., 285, 2010
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3I1A
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![BU of 3i1a by Molmil](/molmil-images/mine/3i1a) | Crystal Structure of apo Spectinomycin Phosphotransferase, APH(9)-Ia | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, Spectinomycin phosphotransferase, ... | Authors: | Berghuis, A.M, Fong, D.H, Lemke, C.T, Hwang, J, Xiong, B. | Deposit date: | 2009-06-25 | Release date: | 2010-01-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the antibiotic resistance factor spectinomycin phosphotransferase from Legionella pneumophila. J.Biol.Chem., 285, 2010
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7ENY
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![BU of 7eny by Molmil](/molmil-images/mine/7eny) | Crystal structure of hydroxysteroid dehydrogenase from Escherichia coli | Descriptor: | 7alpha-hydroxysteroid dehydrogenase | Authors: | Kim, K.-H, Lee, C.W, Pardhe, D.P, Hwang, J, Do, H, Lee, Y.M, Lee, J.H, Oh, T.-J. | Deposit date: | 2021-04-21 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Crystal structure of an apo 7 alpha-hydroxysteroid dehydrogenase reveals key structural changes induced by substrate and co-factor binding. J.Steroid Biochem.Mol.Biol., 212, 2021
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7DVN
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![BU of 7dvn by Molmil](/molmil-images/mine/7dvn) | Crystal structure of a MarR family protein in complex with a lipid-like effector molecule from the psychrophilic bacterium Paenisporosarcina sp. TG-14 | Descriptor: | MarR family transcriptional regulator, PALMITIC ACID | Authors: | Lee, C.W, Hwang, J, Do, H, Lee, J.H. | Deposit date: | 2021-01-14 | Release date: | 2021-11-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of a MarR family protein from the psychrophilic bacterium Paenisporosarcina sp. TG-14 in complex with a lipid-like molecule. Iucrj, 8, 2021
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7D5Y
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![BU of 7d5y by Molmil](/molmil-images/mine/7d5y) | |