3K35
 
 | | Crystal Structure of Human SIRT6 | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent deacetylase sirtuin-6, SULFATE ION, ... | | 著者 | Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Bochkarev, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC) | | 登録日 | 2009-10-01 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and biochemical functions of SIRT6.
J.Biol.Chem., 286, 2011
|
|
3K2L
 | | Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) | | 分子名称: | CHLORIDE ION, Dual specificity tyrosine-phosphorylation-regulated kinase 2, SODIUM ION, ... | | 著者 | Filippakopoulos, P, Myrianthopoulos, V, Soundararajan, M, Krojer, T, Hapka, E, Fedorov, O, Berridge, G, Wang, J, Shrestha, L, Pike, A.C.W, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Mikros, E, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2009-09-30 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition.
Structure, 21, 2013
|
|
7Y62
 | | Crystal structure of human TFEB HLHLZ domain | | 分子名称: | Transcription factor EB | | 著者 | Yang, G, Li, P, Lin, Y, Liu, Z, Sun, H, Zhao, Z, Fang, P, Wang, J. | | 登録日 | 2022-06-18 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
2LA9
 | |
2L7B
 | | NMR Structure of full length apoE3 | | 分子名称: | Apolipoprotein E | | 著者 | Chen, J, Wang, J. | | 登録日 | 2010-12-07 | | 公開日 | 2011-08-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
2LEO
 | |
2L2O
 | |
2LAC
 | |
2LBR
 | |
2LBQ
 | | NMR structure of i6A37_tyrASL | | 分子名称: | RNA (5'-R(*GP*GP*GP*GP*AP*CP*UP*GP*UP*AP*(6IA)P*AP*UP*CP*CP*CP*C)-3') | | 著者 | Denmon, A.P, Wang, J, Nikonowicz, E.P. | | 登録日 | 2011-04-05 | | 公開日 | 2011-08-03 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conformation Effects of Base Modification on the Anticodon Stem-Loop of Bacillus subtilis tRNA(Tyr).
J.Mol.Biol., 412, 2011
|
|
2LEM
 | |
5XMM
 | | FLA-E*01801-167W/S | | 分子名称: | Beta-2-microglobulin, Gag polyprotein, MHC class I antigen alpha chain | | 著者 | Liang, R, Sun, Y, Wang, J, Wu, Y, Zhang, N, Xia, C. | | 登録日 | 2017-05-15 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Major Histocompatibility Complex Class I (FLA-E*01801) Molecular Structure in Domestic Cats Demonstrates Species-Specific Characteristics in Presenting Viral Antigen Peptides
J. Virol., 92, 2018
|
|
5Y3R
 | | Cryo-EM structure of Human DNA-PK Holoenzyme | | 分子名称: | DNA (34-MER), DNA (36-MER), DNA-dependent protein kinase catalytic subunit, ... | | 著者 | Yin, X, Liu, M, Tian, Y, Wang, J, Xu, Y. | | 登録日 | 2017-07-29 | | 公開日 | 2017-09-06 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | Cryo-EM structure of human DNA-PK holoenzyme
Cell Res., 27, 2017
|
|
5WX8
 | | Human herpesvirus 6A immediate early protein 2 C-terminal domain | | 分子名称: | Immediate-early protein 2 | | 著者 | Nishimura, M, Wang, J, Wakata, A, Sakamoto, K, Mori, Y. | | 登録日 | 2017-01-06 | | 公開日 | 2017-08-02 | | 最終更新日 | 2017-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of the DNA-Binding Domain of Human Herpesvirus 6A Immediate Early Protein 2.
J. Virol., 91, 2017
|
|
5XMF
 | | Crystal structure of feline MHC class I for 2,1 angstrom | | 分子名称: | Beta-2-microglobulin, Gag polyprotein, MHC class I antigen alpha chain | | 著者 | Liang, R, Sun, Y, Wang, J, Wu, Y, Zhang, N, Xia, C. | | 登録日 | 2017-05-15 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Major Histocompatibility Complex Class I (FLA-E*01801) Molecular Structure in Domestic Cats Demonstrates Species-Specific Characteristics in Presenting Viral Antigen Peptides
J. Virol., 92, 2018
|
|
5X40
 | | Structure of a CbiO dimer bound with AMPPCP | | 分子名称: | Cobalt ABC transporter ATP-binding protein, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | | 著者 | Bao, Z, Qi, X, Wang, J, Zhang, P. | | 登録日 | 2017-02-09 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure and mechanism of a group-I cobalt energy coupling factor transporter
Cell Res., 27, 2017
|
|
3LM5
 | | Crystal Structure of human Serine/Threonine Kinase 17B (STK17B) in complex with Quercetin | | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, Serine/threonine-protein kinase 17B | | 著者 | Ugochukwu, E, Soundararajan, M, Rellos, P, Fedorov, O, Phillips, C, Wang, J, Hapka, E, Filippakopoulos, P, Chaikuad, A, Pike, A.C.W, Carpenter, L, Vollmar, M, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2010-01-29 | | 公開日 | 2010-03-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation.
J.Med.Chem., 63, 2020
|
|
7DXP
 | | Influenza H5N1 nucleoprotein in complex with nucleotides | | 分子名称: | 1,2-ETHANEDIOL, Nucleoprotein, RNA (5'-R(P*(OMU)P*(OMU)P*(OMU)P*(OMU))-3') | | 著者 | Tang, Y.S, Xu, S, Chen, Y.W, Wang, J.H, Shaw, P.C. | | 登録日 | 2021-01-19 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of influenza nucleoprotein complexed with nucleic acid provide insights into the mechanism of RNA interaction.
Nucleic Acids Res., 49, 2021
|
|
3PKI
 | | Human SIRT6 crystal structure in complex with ADP ribose | | 分子名称: | NAD-dependent deacetylase sirtuin-6, SULFATE ION, UNKNOWN ATOM OR ION, ... | | 著者 | Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Bochkarev, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC) | | 登録日 | 2010-11-11 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structure and biochemical functions of SIRT6.
J.Biol.Chem., 286, 2011
|
|
6A4I
 | | Crystal Structure of human TDO inhibitor complex | | 分子名称: | 1-(6-chloro-1H-indazol-4-yl)cyclohexan-1-ol, CITRIC ACID, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Fu, G, Wang, J, Luo, G, Wu, G, Qian, K. | | 登録日 | 2018-06-20 | | 公開日 | 2018-07-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal Structure of human TDO inhibitor complex
To Be Published
|
|
3PKJ
 | | Human SIRT6 crystal structure in complex with 2'-N-Acetyl ADP ribose | | 分子名称: | NAD-dependent deacetylase sirtuin-6, SULFATE ION, UNKNOWN ATOM OR ION, ... | | 著者 | Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Walker, J.R, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC) | | 登録日 | 2010-11-11 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structure and biochemical functions of SIRT6.
J.Biol.Chem., 286, 2011
|
|
7XIV
 | | Structural insight into the interactions between Lloviu virus VP30 and nucleoprotein | | 分子名称: | Nucleocapsid protein,Minor nucleoprotein VP30 | | 著者 | Dong, S.S, Qin, X.C, Sun, W.Y, Luan, F.C, Wang, J.J, Ma, L, Li, X.X, Yang, G.X, Hao, C.Y. | | 登録日 | 2022-04-14 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | | 主引用文献 | Structural insights into the interactions between lloviu virus VP30 and nucleoprotein.
Biochem.Biophys.Res.Commun., 616, 2022
|
|
7XU2
 | | Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | 著者 | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | | 登録日 | 2022-05-18 | | 公開日 | 2022-07-20 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
|
|
7XU0
 | | Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-211 Conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | 著者 | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | | 登録日 | 2022-05-18 | | 公開日 | 2022-07-20 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
|
|
7XTZ
 | | Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-1 Conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | 著者 | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | | 登録日 | 2022-05-18 | | 公開日 | 2022-07-20 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
|
|
