6A4I

Crystal Structure of human TDO inhibitor complex

Summary for 6A4I

• Entry DOI: 10.2210/pdb6a4i/pdb
• Descriptor: Tryptophan 2,3-dioxygenase, PROTOPORPHYRIN IX CONTAINING FE, 1-(6-chloro-1H-indazol-4-yl)cyclohexan-1-ol, ... (5 entities in total)
• Functional Keywords: tdo holoenzyme oxygenase active site inhibitor tetramer, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 188952.06

Authors

Fu, G.,Wang, J.,Luo, G.,Wu, G.,Qian, K. (deposition date: 2018-06-20, release date: 2018-07-18, Last modification date: 2024-03-27)

• Primary citation: Fu, G.,Wang, J.,Luo, G.,Wu, G.,Qian, K.; Crystal Structure of human TDO inhibitor complex; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.65 Å)