3VBR
| Crystal structure of formaldehyde treated empty human Enterovirus 71 particle (room temperature) | 分子名称: | Genome Polyprotein, capsid protein VP0, capsid protein VP1, ... | 著者 | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | 登録日 | 2012-01-02 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat.Struct.Mol.Biol., 19, 2012
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6KHX
| Crystal structure of Prx from Akkermansia muciniphila | 分子名称: | CALCIUM ION, Peroxiredoxin | 著者 | Li, M, Wang, J, Xu, W, Wang, Y, Zhang, M, Wang, M. | 登録日 | 2019-07-16 | 公開日 | 2020-02-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Crystal structure of Akkermansia muciniphila peroxiredoxin reveals a novel regulatory mechanism of typical 2-Cys Prxs by a distinct loop. Febs Lett., 594, 2020
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6WGB
| Crystal structure of the fab portion of dupilumab | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | 登録日 | 2020-04-05 | 公開日 | 2020-09-16 | 最終更新日 | 2020-09-23 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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3VBF
| Crystal structure of formaldehyde treated human Enterovirus 71 (space group I23) | 分子名称: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Genome Polyprotein, ... | 著者 | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | 登録日 | 2012-01-02 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat.Struct.Mol.Biol., 19, 2012
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6WG8
| Fab portion of dupilumab with Crystal Kappa design | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain, GLYCEROL | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | 登録日 | 2020-04-05 | 公開日 | 2020-09-16 | 最終更新日 | 2020-09-23 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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3VBO
| Crystal structure of formaldehyde treated empty human Enterovirus 71 particle (cryo at 100K) | 分子名称: | Genome Polyprotein, capsid protein VP1, capsid protein VP2, ... | 著者 | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | 登録日 | 2012-01-02 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat.Struct.Mol.Biol., 19, 2012
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3F4M
| Crystal structure of TIPE2 | 分子名称: | CHLORIDE ION, Tumor necrosis factor, alpha-induced protein 8-like protein 2 | 著者 | Zhang, X, Wang, J, Shi, Y. | 登録日 | 2008-11-01 | 公開日 | 2009-03-17 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | 主引用文献 | Crystal structure of TIPE2 provides insights into immune homeostasis Nat.Struct.Mol.Biol., 16, 2009
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5YEG
| Crystal structure of CTCF ZFs4-8-Hs5-1a complex | 分子名称: | DNA (5'-D(*AP*CP*TP*TP*TP*AP*AP*CP*CP*AP*GP*CP*AP*GP*AP*GP*GP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*GP*CP*TP*GP*GP*TP*TP*AP*AP*AP*G)-3'), Transcriptional repressor CTCF, ... | 著者 | Yin, M, Wang, J, Wang, M, Li, X. | 登録日 | 2017-09-17 | 公開日 | 2017-11-29 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
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7TOB
| Crystal structure of the SARS-CoV-2 Omicron main protease (Mpro) in complex with inhibitor GC376 | 分子名称: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER | 著者 | Sacco, M.D, Wang, J, Chen, Y. | 登録日 | 2022-01-24 | 公開日 | 2022-02-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The P132H mutation in the main protease of Omicron SARS-CoV-2 decreases thermal stability without compromising catalysis or small-molecule drug inhibition. Cell Res., 32, 2022
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8T7C
| Crystal structure of human phospholipase C gamma 2 | 分子名称: | 1,2-ETHANEDIOL, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, CALCIUM ION | 著者 | Chen, Y, Choi, H, Zhuang, N, Hu, L, Qian, D, Wang, J. | 登録日 | 2023-06-20 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The crystal and cryo-EM structures of PLCg2 reveal dynamic inter-domain recognitions in autoinhibition To Be Published
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8J22
| Cryo-EM structure of FFAR2 complex bound with TUG-1375 | 分子名称: | (2R,4R)-2-(2-chlorophenyl)-3-[4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]carbonyl-1,3-thiazolidine-4-carboxylic acid, Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Tai, L, Li, F, Sun, X, Tang, W, Wang, J. | 登録日 | 2023-04-14 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3. Cell Res., 34, 2024
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8J24
| Cryo-EM structure of FFAR2 complex bound with acetic acid | 分子名称: | ACETATE ION, Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Tai, L, Li, F, Tang, W, Sun, X, Wang, J. | 登録日 | 2023-04-14 | 公開日 | 2024-01-24 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3. Cell Res., 34, 2024
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8J20
| Cryo-EM structure of FFAR3 bound with valeric acid and AR420626 | 分子名称: | (4R)-N-[2,5-bis(chloranyl)phenyl]-4-(furan-2-yl)-2-methyl-5-oxidanylidene-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide, Free fatty acid receptor 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Tai, L, Li, F, Sun, X, Tang, W, Wang, J. | 登録日 | 2023-04-14 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3. Cell Res., 34, 2024
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8J21
| Cryo-EM structure of FFAR3 complex bound with butyrate acid | 分子名称: | Free fatty acid receptor 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Tai, L, Li, F, Sun, X, Tang, W, Wang, J. | 登録日 | 2023-04-14 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3. Cell Res., 34, 2024
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6XBI
| Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW248 | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Sacco, M, Ma, C, Wang, J, Chen, Y. | 登録日 | 2020-06-06 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L. Sci Adv, 6, 2020
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7TUK
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6IFZ
| Type III-A Csm complex, Cryo-EM structure of Csm-CTR2-ssDNA complex | 分子名称: | CTR2, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-21 | 公開日 | 2018-12-12 | 最終更新日 | 2019-01-23 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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7TUL
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6XBG
| Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW246 | 分子名称: | 3C-like proteinase, GLYCEROL, SODIUM ION, ... | 著者 | Sacco, M, Ma, C, Wang, J, Chen, Y. | 登録日 | 2020-06-05 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L. Sci Adv, 6, 2020
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4DJK
| Structure of glutamate-GABA antiporter GadC | 分子名称: | Probable glutamate/gamma-aminobutyrate antiporter | 著者 | Ma, D, Lu, P.L, Yan, C.Y, Fan, C, Yin, P, Wang, J.W, Shi, Y.G. | 登録日 | 2012-02-02 | 公開日 | 2012-03-14 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.097 Å) | 主引用文献 | Structure and mechanism of a glutamate-GABA antiporter Nature, 483, 2012
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5YEL
| Crystal structure of CTCF ZFs6-11-gb7CSE | 分子名称: | DNA (26-MER), Transcriptional repressor CTCF, ZINC ION | 著者 | Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. | 登録日 | 2017-09-18 | 公開日 | 2017-11-29 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
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4DJI
| Structure of glutamate-GABA antiporter GadC | 分子名称: | Probable glutamate/gamma-aminobutyrate antiporter | 著者 | Ma, D, Lu, P.L, Yan, C.Y, Fan, C, Yin, P, Wang, J.W, Shi, Y.G. | 登録日 | 2012-02-02 | 公開日 | 2012-03-14 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.187 Å) | 主引用文献 | Structure and mechanism of a glutamate-GABA antiporter Nature, 483, 2012
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6IFU
| Cryo-EM structure of type III-A Csm-CTR2-dsDNA complex | 分子名称: | CTR2, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-21 | 公開日 | 2018-12-12 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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6IFR
| Type III-A Csm complex, Cryo-EM structure of Csm-NTR, ATP bound | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Type III-A CRISPR-associated RAMP protein Csm3, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-21 | 公開日 | 2018-12-12 | 最終更新日 | 2019-01-23 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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6IFK
| Cryo-EM structure of type III-A Csm-CTR1 complex, AMPPNP bound | 分子名称: | CTR1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-20 | 公開日 | 2018-12-12 | 最終更新日 | 2019-01-23 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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