2KO1
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![BU of 2ko1 by Molmil](/molmil-images/mine/2ko1) | Solution NMR structure of the ACT domain from GTP pyrophosphokinase of Chlorobium tepidum. Northeast Structural Genomics Consortium Target CtR148A | 分子名称: | GTP pyrophosphokinase | 著者 | Eletsky, A, Garcia, E, Wang, H, Ciccosanti, C, Jiang, M, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Lee, H, Prestegard, J.H, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-09-08 | 公開日 | 2009-09-29 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of the ACT domain from GTP pyrophosphokinase of Chlorobium tepidum To be Published
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6FWB
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![BU of 6fwb by Molmil](/molmil-images/mine/6fwb) | Crystal structure of Mat2A at 1.79 Angstron resolution | 分子名称: | GLYCEROL, S-adenosylmethionine synthase isoform type-2, SODIUM ION, ... | 著者 | Zhou, A, Wei, Z, Bai, J, Wang, H. | 登録日 | 2018-03-06 | 公開日 | 2019-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes. Ebiomedicine, 39, 2019
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4AOJ
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![BU of 4aoj by Molmil](/molmil-images/mine/4aoj) | Human TrkA in complex with the inhibitor AZ-23 | 分子名称: | 5-chloranyl-N2-[(1S)-1-(5-fluoranylpyridin-2-yl)ethyl]-N4-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine, HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR, ZINC ION | 著者 | Wang, T, Lamb, M.L, Block, M.H, Davies, A.M, Han, Y, Hoffmann, E, Ioannidis, S, Josey, J.A, Liu, Z, Lyne, P.D, MacIntyre, T, Mohr, P.J, Omer, C.A, Sjogren, T, Thress, K, Wang, B, Wang, H, Yu, D, Zhang, H. | 登録日 | 2012-03-28 | 公開日 | 2012-08-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Discovery of Disubstituted Imidazo[4,5-B]Pyridines and Purines as Potent Trka Inhibitors Acs Med.Chem.Lett., 3, 2012
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8HLL
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![BU of 8hll by Molmil](/molmil-images/mine/8hll) | Crystal structure of p53/BCL2 fusion complex (complex 1) | 分子名称: | Apoptosis regulator Bcl-2, Cellular tumor antigen p53, ZINC ION | 著者 | Wei, H, Guo, M, Wang, H, Chen, Y. | 登録日 | 2022-11-30 | 公開日 | 2023-07-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity. Nat Commun, 14, 2023
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8HLN
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![BU of 8hln by Molmil](/molmil-images/mine/8hln) | Crystal structure of p53/BCL2 fusion complex(complex3) | 分子名称: | Apoptosis regulator Bcl-2, Cellular tumor antigen p53, ZINC ION | 著者 | Guo, M, Wei, H, Wang, H, Chen, Y. | 登録日 | 2022-11-30 | 公開日 | 2023-07-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.354 Å) | 主引用文献 | Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity. Nat Commun, 14, 2023
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8HLM
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![BU of 8hlm by Molmil](/molmil-images/mine/8hlm) | Crystal structure of p53/BCL2 fusion complex (complex 2) | 分子名称: | Apoptosis regulator Bcl-2, Cellular tumor antigen p53, ZINC ION | 著者 | Guo, M, Wang, H, Wei, H, Chen, Y. | 登録日 | 2022-11-30 | 公開日 | 2023-07-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.522 Å) | 主引用文献 | Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity. Nat Commun, 14, 2023
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5KQA
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![BU of 5kqa by Molmil](/molmil-images/mine/5kqa) | Crystal structure of buckwheat glutaredoxin-glutathione complex | 分子名称: | GLUTATHIONE, Glutaredoxin-glutathione complex | 著者 | Zhang, X, Wang, W, Zhao, Y, Wang, Z, Wang, H. | 登録日 | 2016-07-06 | 公開日 | 2017-07-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural insights into the binding of buckwheat glutaredoxin with GSH and regulation of its catalytic activity J. Inorg. Biochem., 173, 2017
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5XMK
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![BU of 5xmk by Molmil](/molmil-images/mine/5xmk) | Cryo-EM structure of the ATP-bound Vps4 mutant-E233Q complex with Vta1 (masked) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Vacuolar protein sorting-associated protein 4, Vacuolar protein sorting-associated protein VTA1 | 著者 | Sun, S, Li, L, Yang, F, Wang, X, Fan, F, Li, X, Wang, H, Sui, S. | 登録日 | 2017-05-15 | 公開日 | 2017-08-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution Nat Commun, 8, 2017
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5XMI
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![BU of 5xmi by Molmil](/molmil-images/mine/5xmi) | Cryo-EM Structure of the ATP-bound VPS4 mutant-E233Q hexamer (masked) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Vacuolar protein sorting-associated protein 4 | 著者 | Sun, S, Li, L, Yang, F, Wang, X, Fan, F, Li, X, Wang, H, Sui, S. | 登録日 | 2017-05-15 | 公開日 | 2017-08-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution Nat Commun, 8, 2017
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3DD4
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![BU of 3dd4 by Molmil](/molmil-images/mine/3dd4) | |
2K5P
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![BU of 2k5p by Molmil](/molmil-images/mine/2k5p) | NMR Solution Structure of a Thiamine Biosynthesis Protein from Geobacter Metallireducens: Northeast Structural Genomics Consortium Target GmR137 | 分子名称: | thiamine-biosynthesis protein | 著者 | Mani, R, Wang, H, Jiang, M, Magliaqui, M, Xiao, R, Nair, R, Baran, M.C, Gurla, S.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-06-30 | 公開日 | 2008-08-26 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Solution Structure of a Thiamine Biosynthesis Protein from Geobacter Metallireducens: Northeast Structural Genomics Consortium Target GmR137 To be Published
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2KCZ
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![BU of 2kcz by Molmil](/molmil-images/mine/2kcz) | Solution NMR structure of the C-terminal domain of protein DR_A0006 from Deinococcus radiodurans. Northeast Structural Genomics Consortium Target DrR147D | 分子名称: | Uncharacterized protein DR_A0006 | 著者 | Mills, J.L, Ghosh, A, Garcia, E, Wang, H, Ciccosanti, C, Xiao, R, Nair, R, Everett, J.K, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-12-31 | 公開日 | 2009-01-20 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of the C-Terminal Domain of Protein DR_A0006 from Deinococcus radiodurans. Northeast Structural Genomics Consortium Target DrR147D. To be Published
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2K5R
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![BU of 2k5r by Molmil](/molmil-images/mine/2k5r) | Solution NMR Structure of XF2673 from Xylella fastidiosa. Northeast Structural Genomics Consortium Target XfR39 | 分子名称: | uncharacterized protein XF2673 | 著者 | Tang, Y, Wang, H, Jiang, M, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-06-30 | 公開日 | 2008-08-26 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of XF2673 from Xylella fastidiosa. Northeast Structural Genomics
Consortium Target XfR39 To be Published
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2KKS
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![BU of 2kks by Molmil](/molmil-images/mine/2kks) | Solution Structure Of Protein DSY2949 From Desulfitobacterium hafniense. Northeast Structural Genomics Consortium Target DhR27 | 分子名称: | Uncharacterized protein | 著者 | Wu, Y, Mills, J.L, Wang, H, Ciccosanti, C, Jiang, M, Sukumaran, D, Zhang, Q, Nair, R, Rost, B, Acton, T, Xiao, R, Swapna, G.V.T, Everett, J, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-06-29 | 公開日 | 2009-08-25 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure Of Protein DSY2949 From Desulfitobacterium hafniense. Northeast Structural Genomics Consortium Target DhR27 To be Published
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2KKP
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![BU of 2kkp by Molmil](/molmil-images/mine/2kkp) | Solution NMR structure of the phage integrase SAM-like Domain from Moth 1796 from Moorella thermoacetica. Northeast Structural Genomics Consortium Target MtR39K (residues 64-171). | 分子名称: | Phage integrase | 著者 | Ramelot, T.A, Wang, H, Ciccosanti, C, Jang, M, Nair, R, Rost, B, Swapna, G, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-06-26 | 公開日 | 2009-09-08 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of the phage integrase SAM-like Domain from Moth 1796
from Moorella thermoacetica. Northeast
Structural Genomics Consortium Target MtR39K (residues 64-171). To be Published
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2KHD
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![BU of 2khd by Molmil](/molmil-images/mine/2khd) | Solution NMR structure of VC_A0919 from Vibrio cholerae. Northeast Structural Genomics Consortium Target VcR52 | 分子名称: | Uncharacterized protein VC_A0919 | 著者 | Ramelot, T.A, Cort, J.R, Wang, H, Ciccosanti, C, Jiang, M, Liu, J, Rost, B, Swapna, G.V.T, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-04-02 | 公開日 | 2009-06-16 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of VC_A0919 from Vibrio cholerae. Northeast Structural Genomics Consortium Target VcR52. To be Published
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8HJE
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![BU of 8hje by Molmil](/molmil-images/mine/8hje) | Vismodegib binds to the catalytical domain of human Ubiquitin-Specific Protease 28 | 分子名称: | 2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide, Ubiquitin carboxyl-terminal hydrolase 28 | 著者 | Shi, L, Wang, H, Xu, Z, Xiong, B, Zhang, N. | 登録日 | 2022-11-23 | 公開日 | 2023-05-03 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structure-based discovery of potent USP28 inhibitors derived from Vismodegib. Eur.J.Med.Chem., 254, 2023
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7O4Z
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![BU of 7o4z by Molmil](/molmil-images/mine/7o4z) | Crystal structure of the carbonic anhydrase-like domain of CcmM from Synechococcus elongatus (strain PCC 7942) | 分子名称: | CHLORIDE ION, Carboxysome assembly protein CcmM, NICKEL (II) ION | 著者 | Zang, K, Wang, H, Hartl, F.U, Hayer-Hartl, M. | 登録日 | 2021-04-07 | 公開日 | 2021-11-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Scaffolding protein CcmM directs multiprotein phase separation in beta-carboxysome biogenesis. Nat.Struct.Mol.Biol., 28, 2021
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7O54
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![BU of 7o54 by Molmil](/molmil-images/mine/7o54) | Crystal structure of the carbonic anhydrase-like domain of CcmM in complex with the C-terminal 17 residues of CcaA from Synechococcus elongatus (strain PCC 7942) | 分子名称: | CHLORIDE ION, Carbonic anhydrase, Carboxysome assembly protein CcmM, ... | 著者 | Zang, K, Wang, H, Hartl, F.U, Hayer-Hartl, M. | 登録日 | 2021-04-07 | 公開日 | 2021-11-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Scaffolding protein CcmM directs multiprotein phase separation in beta-carboxysome biogenesis. Nat.Struct.Mol.Biol., 28, 2021
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3C4A
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![BU of 3c4a by Molmil](/molmil-images/mine/3c4a) | Crystal structure of vioD hydroxylase in complex with FAD from Chromobacterium violaceum. Northeast Structural Genomics Consortium Target CvR158 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Probable tryptophan hydroxylase vioD | 著者 | Forouhar, F, Neely, H, Seetharaman, J, Janjua, H, Xiao, R, Maglaqui, M, Wang, H, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-01-29 | 公開日 | 2008-02-05 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of vioD hydroxylase in complex with FAD from Chromobacterium violaceum. To be Published
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8T6J
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![BU of 8t6j by Molmil](/molmil-images/mine/8t6j) | |
7YPN
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![BU of 7ypn by Molmil](/molmil-images/mine/7ypn) | Crystal structure of transaminase CC1012 mutant M9 complexed with PLP | 分子名称: | 1,2-ETHANEDIOL, Aspartate aminotransferase family protein, DI(HYDROXYETHYL)ETHER, ... | 著者 | Yang, L, Wang, H, Wei, D. | 登録日 | 2022-08-03 | 公開日 | 2023-05-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.049 Å) | 主引用文献 | Mechanism-Guided Computational Design of omega-Transaminase by Reprograming of High-Energy-Barrier Steps. Angew.Chem.Int.Ed.Engl., 61, 2022
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7YPM
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![BU of 7ypm by Molmil](/molmil-images/mine/7ypm) | Crystal structure of transaminase CC1012 complexed with PLP and L-alanine | 分子名称: | 1,2-ETHANEDIOL, ALANINE, Aspartate aminotransferase family protein, ... | 著者 | Yang, L, Wang, H, Wei, D. | 登録日 | 2022-08-03 | 公開日 | 2023-05-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.984 Å) | 主引用文献 | Mechanism-Guided Computational Design of omega-Transaminase by Reprograming of High-Energy-Barrier Steps. Angew.Chem.Int.Ed.Engl., 61, 2022
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6QIM
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![BU of 6qim by Molmil](/molmil-images/mine/6qim) | Structure of AtPIP2;4 | 分子名称: | Probable aquaporin PIP2-4 | 著者 | Schoebel, S, Wang, H. | 登録日 | 2019-01-21 | 公開日 | 2019-11-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Characterization of aquaporin-driven hydrogen peroxide transport. Biochim Biophys Acta Biomembr, 1862, 2020
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3CWI
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![BU of 3cwi by Molmil](/molmil-images/mine/3cwi) | Crystal structure of thiamine biosynthesis protein (ThiS) from Geobacter metallireducens. Northeast Structural Genomics Consortium Target GmR137 | 分子名称: | Thiamine-biosynthesis protein ThiS | 著者 | Forouhar, F, Abashidze, M, Seetharaman, J, Mao, L, Janjua, H, Xiao, R, Maglaqui, M, Ciccosanti, C, Foote, E.L, Wang, H, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-04-21 | 公開日 | 2008-05-06 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of thiamine biosynthesis protein (ThiS) from Geobacter metallireducens. To be Published
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