1XOE
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![BU of 1xoe by Molmil](/molmil-images/mine/1xoe) | N9 Tern influenza neuraminidase complexed with (2R,4R,5R)-5-(1-Acetylamino-3-methyl-butyl-pyrrolidine-2, 4-dicarobyxylic acid 4-methyl esterdase complexed with | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[1-(ACETYLAMINO)-3-METHYLBUTYL]-4-(METHOXYCARBONYL)PROLINE, Neuraminidase, ... | Authors: | Wang, G.T, Wang, S, Gentles, R, Sowin, T, Maring, C.J, Kempf, D.J, Kati, W.M, Stoll, V, Stewart, K.D, Laver, G. | Deposit date: | 2004-10-06 | Release date: | 2005-01-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase
containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core. Bioorg.Med.Chem.Lett., 15, 2005
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6XSP
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6XSQ
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6XT3
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1XOG
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![BU of 1xog by Molmil](/molmil-images/mine/1xog) | N9 Tern Influenza neuraminidase complexed with a 2,5-Disubstituted tetrahydrofuran-5-carboxylic acid | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[1-(ACETYLAMINO)-3-METHYLBUTYL]-2,5-ANHYDRO-3,4-DIDEOXY-4-(METHOXYCARBONYL)PENTONIC ACID, Neuraminidase, ... | Authors: | Wang, G.T, Wang, S, Gentles, R, Sowin, T, Maring, C.J, Kempf, D.J, Kati, W.M, Stoll, V, Stewart, K.D, Laver, G. | Deposit date: | 2004-10-06 | Release date: | 2005-01-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core. Bioorg.Med.Chem.Lett., 15, 2005
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8K5O
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![BU of 8k5o by Molmil](/molmil-images/mine/8k5o) | Cryo-EM structure of the RC-LH core comples from Halorhodospira halochloris | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-O-octyl-beta-D-glucopyranose, ... | Authors: | Wang, G.-L, Qi, C.-H, Yu, L.-J. | Deposit date: | 2023-07-22 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.42 Å) | Cite: | Structural insights into the unusual core photocomplex from a triply extremophilic purple bacterium, Halorhodospira halochloris. J Integr Plant Biol, 2024
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1GW3
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1GW4
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3H98
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![BU of 3h98 by Molmil](/molmil-images/mine/3h98) | Crystal structure of HCV NS5b 1b with (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyrimidine derivative | Descriptor: | GLYCEROL, N-{3-[5-hydroxy-8-(3-methylbutyl)-7-oxo-7,8-dihydroimidazo[1,2-a]pyrimidin-6-yl]-1,1-dioxido-4H-1,2,4-benzothiadiazin-7-yl}methanesulfonamide, RNA-directed RNA polymerase | Authors: | Wang, G, Lei, H, Wang, X, Das, D, Mackinnon, C, Montalbetti, C.A.G, Mears, R, Gai, X, Bailey, S, Ruhrmund, D, Hooi, L, Misialek, S, Rajagopalan, R, Cheng, R.K.Y, Barker, J.L, Felicetti, B, Stoycheva, A, Buckman, B, Kossen, K, Seiwert, S, Beigelmana, L. | Deposit date: | 2009-04-30 | Release date: | 2009-10-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives. Bioorg.Med.Chem.Lett., 19, 2009
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8IUG
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![BU of 8iug by Molmil](/molmil-images/mine/8iug) | Cryo-EM structure of the RC-LH core complex from roseiflexus castenholzii | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-O-octyl-beta-D-glucopyranose, ... | Authors: | Wang, G.-L, Qi, C.-H, Yu, L.-J. | Deposit date: | 2023-03-24 | Release date: | 2023-11-22 | Last modified: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | New insights on the photocomplex of Roseiflexus castenholzii revealed from comparisons of native and carotenoid-depleted complexes. J.Biol.Chem., 299, 2023
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1NH9
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![BU of 1nh9 by Molmil](/molmil-images/mine/1nh9) | Crystal Structure of a DNA Binding Protein Mja10b from the hyperthermophile Methanococcus jannaschii | Descriptor: | DNA-binding protein Alba | Authors: | Wang, G, Bartlam, M, Guo, R, Yang, H, Xue, H, Liu, Y, Huang, L, Rao, Z. | Deposit date: | 2002-12-19 | Release date: | 2003-12-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a DNA binding protein from the hyperthermophilic euryarchaeon Methanococcus jannaschii Protein Sci., 12, 2003
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8IUN
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![BU of 8iun by Molmil](/molmil-images/mine/8iun) | Cryo-EM structure of the CRT-LESS RC-LH core complex from roseiflexus castenholzii | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-O-octyl-beta-D-glucopyranose, ... | Authors: | Wang, G.-L, Qi, C.-H, Yu, L.-J. | Deposit date: | 2023-03-24 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | New insights on the photocomplex of Roseiflexus castenholzii revealed from comparisons of native and carotenoid-depleted complexes. J.Biol.Chem., 299, 2023
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6PVY
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6MK8
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1OEF
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![BU of 1oef by Molmil](/molmil-images/mine/1oef) | PEPTIDE OF HUMAN APOE RESIDUES 263-286, NMR, 5 STRUCTURES AT PH 4.8, 37 DEGREES CELSIUS AND PEPTIDE:SDS MOLE RATIO OF 1:90 | Descriptor: | APOLIPOPROTEIN E | Authors: | Wang, G, Pierens, G.K, Treleaven, W.D, Sparrow, J.T, Cushley, R.J. | Deposit date: | 1996-03-16 | Release date: | 1996-12-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Conformations of human apolipoprotein E(263-286) and E(267-289) in aqueous solutions of sodium dodecyl sulfate by CD and 1H NMR. Biochemistry, 35, 1996
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6NM3
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![BU of 6nm3 by Molmil](/molmil-images/mine/6nm3) | NMR structure of WW295 | Descriptor: | WW295 peptide | Authors: | Wang, G, Zarena, D. | Deposit date: | 2019-01-10 | Release date: | 2020-07-15 | Last modified: | 2020-09-09 | Method: | SOLUTION NMR | Cite: | Two distinct amphipathic peptide antibiotics with systemic efficacy. Proc.Natl.Acad.Sci.USA, 117, 2020
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6NM2
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![BU of 6nm2 by Molmil](/molmil-images/mine/6nm2) | NMR Structure of WW291 | Descriptor: | WW291 peptide | Authors: | Wang, G, Zarena, D. | Deposit date: | 2019-01-10 | Release date: | 2020-07-15 | Last modified: | 2020-09-09 | Method: | SOLUTION NMR | Cite: | The pi Configuration of the WWW Motif of a Short Trp-Rich Peptide Is Critical for Targeting Bacterial Membranes, Disrupting Preformed Biofilms, and Killing Methicillin-Resistant Staphylococcus aureus. Biochemistry, 56, 2017
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1OEG
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![BU of 1oeg by Molmil](/molmil-images/mine/1oeg) | PEPTIDE OF HUMAN APOE RESIDUES 267-289, NMR, 5 STRUCTURES AT PH 6.0, 37 DEGREES CELSIUS AND PEPTIDE:SDS MOLE RATIO OF 1:90 | Descriptor: | APOLIPOPROTEIN E | Authors: | Wang, G, Pierens, G.K, Treleaven, W.D, Sparrow, J.T, Cushley, R.J. | Deposit date: | 1996-03-16 | Release date: | 1996-12-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Conformations of human apolipoprotein E(263-286) and E(267-289) in aqueous solutions of sodium dodecyl sulfate by CD and 1H NMR. Biochemistry, 35, 1996
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7ENQ
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![BU of 7enq by Molmil](/molmil-images/mine/7enq) | Crystal structure of human NAMPT in complex with compound NAT | Descriptor: | 2-(2-~{tert}-butylphenoxy)-~{N}-(4-hydroxyphenyl)ethanamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION | Authors: | Wang, G, Wu, C, Liu, M, Yao, H, Li, C, Wang, L, Tang, Y. | Deposit date: | 2021-04-19 | Release date: | 2022-05-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.204966 Å) | Cite: | Discovery of small-molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and their preclinical neuroprotective activity. Cell Res., 32, 2022
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5KI0
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![BU of 5ki0 by Molmil](/molmil-images/mine/5ki0) | NMR structure of human antimicrobial peptide KAMP-19 | Descriptor: | Antimicrobial peptide KAMP-19 | Authors: | Wang, G. | Deposit date: | 2016-06-16 | Release date: | 2016-11-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Membrane-Active Epithelial Keratin 6A Fragments (KAMPs) Are Unique Human Antimicrobial Peptides with a Non-alpha beta Structure. Front Microbiol, 7, 2016
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6PVZ
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1O53
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2F3A
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2FBS
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1VM5
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![BU of 1vm5 by Molmil](/molmil-images/mine/1vm5) | |