8P7J
Crystal structure of MAP2K6 with a covalent compound GCL96
Summary for 8P7J
Entry DOI | 10.2210/pdb8p7j/pdb |
Descriptor | Dual specificity mitogen-activated protein kinase kinase 6, N-[3-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]prop-2-enamide (3 entities in total) |
Functional Keywords | kinase, covalent, inhibitor, map2k6, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 66026.36 |
Authors | Wang, G.Q.,Seidler, N.,Roehm, S.,Gehringer, M.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2023-05-30, release date: 2023-07-05, Last modification date: 2024-11-13) |
Primary citation | Wang, G.Q.,Seidler, N.,Roehm, S.,Gehringer, M.,Knapp, S.,Structural Genomics Consortium (SGC) Crystal structure of MAP2K6 with a covalent compound GCL96 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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