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8P7J

Crystal structure of MAP2K6 with a covalent compound GCL96

Summary for 8P7J
Entry DOI10.2210/pdb8p7j/pdb
DescriptorDual specificity mitogen-activated protein kinase kinase 6, N-[3-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]prop-2-enamide (3 entities in total)
Functional Keywordskinase, covalent, inhibitor, map2k6, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight66026.36
Authors
Wang, G.Q.,Seidler, N.,Roehm, S.,Gehringer, M.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2023-05-30, release date: 2023-07-05, Last modification date: 2024-11-13)
Primary citationWang, G.Q.,Seidler, N.,Roehm, S.,Gehringer, M.,Knapp, S.,Structural Genomics Consortium (SGC)
Crystal structure of MAP2K6 with a covalent compound GCL96
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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