8P7J

Crystal structure of MAP2K6 with a covalent compound GCL96

Summary for 8P7J

• Entry DOI: 10.2210/pdb8p7j/pdb
• Descriptor: Dual specificity mitogen-activated protein kinase kinase 6, N-[3-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]prop-2-enamide (3 entities in total)
• Functional Keywords: kinase, covalent, inhibitor, map2k6, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 66026.36

Authors

Wang, G.Q.,Seidler, N.,Roehm, S.,Gehringer, M.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2023-05-30, release date: 2023-07-05, Last modification date: 2023-08-09)

• Primary citation: Wang, G.Q.,Seidler, N.,Roehm, S.,Gehringer, M.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of MAP2K6 with a covalent compound GCL96; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)