9FET

Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to JA-47

Summary for 9FET

• Entry DOI: 10.2210/pdb9fet/pdb
• Descriptor: Serine/threonine-protein kinase VRK2, [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrile (3 entities in total)
• Functional Keywords: kinase, vrk2, inhibitor, ja-296, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37119.60

Authors

Wang, G.Q.,Amrhein, J.A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2024-05-21, release date: 2024-09-11)

• Primary citation: Wang, G.Q.,Amrhein, J.A.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to JA-47; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)