9FET
Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to JA-47
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase VRK2 | polymer | 324 | 36788.2 | 1 | UniProt (Q86Y07) Pfam (PF00069) | Homo sapiens (human) | Vaccinia-related kinase 2 |
| 2 | B (A) | [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrile | non-polymer | 331.4 | 1 | Chemie (REB) | |||
| 3 | C (A) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A: 14 - 335 (UniProt: Q86Y07)
| PDB | External Database | Details |
|---|---|---|
| Ser 12 | - | expression tag |
| Met 13 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36788.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 331.4 | |
| All* | Total formula weight | 37119.6 |
