8PM3

Crystal structure of MAP2K6 with a covalent compound GCL94

Summary for 8PM3

• Entry DOI: 10.2210/pdb8pm3/pdb
• Descriptor: Dual specificity mitogen-activated protein kinase kinase 6, ~{N}-[3-(2-azanylpyridin-4-yl)phenyl]propanamide (3 entities in total)
• Functional Keywords: kinase, covalent, inhibitor, map2k6, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 131964.69

Authors

Wang, G.Q.,Seidler, N.,Roehm, S.,Gehringer, M.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2023-06-28, release date: 2023-09-20)

• Primary citation: Wang, G.Q.,Seidler, N.,Roehm, S.,Gehringer, M.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of MAP2K6 with a covalent compound GCL94; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)