8Q1Z

Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to JA-296

Summary for 8Q1Z

• Entry DOI: 10.2210/pdb8q1z/pdb
• Descriptor: Serine/threonine-protein kinase VRK2, 2-[4-[[4-[(3-~{tert}-butyl-1~{H}-pyrazol-5-yl)amino]pyrimidin-2-yl]amino]phenyl]ethanenitrile (3 entities in total)
• Functional Keywords: inhibitor, kinase, vrk2, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37135.65

Authors

Wang, G.Q.,Amrhein, J.A.,Knapp, S. (deposition date: 2023-08-01, release date: 2023-08-16)

• Primary citation: Wang, G.Q.,Amrhein, J.A.,Knapp, S.; Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to JA-296; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)