4MRM
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![BU of 4mrm by Molmil](/molmil-images/mine/4mrm) | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist phaclofen | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | Authors: | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | Deposit date: | 2013-09-17 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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4LI5
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![BU of 4li5 by Molmil](/molmil-images/mine/4li5) | EGFR-K IN COMPLEX WITH N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxy-phenyl] Prop-2-enamide | Descriptor: | Epidermal growth factor receptor, N-(3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamide, SODIUM ION | Authors: | Debreczeni, J.E, Seiffert, G.B, Kiefersauer, R, Augustin, M, Nagel, S, Ward, R, Anderton, M, Ashton, S, Bethel, P, Box, M, Butterworth, S, Colclough, N, Chroley, C, Chuaqui, C, Cross, D, Eberlein, C, Finlay, R, Hill, G, Grist, M, Klinowska, T, Lane, C, Martin, S, Orme, J, Smith, P, Wang, F, Waring, M. | Deposit date: | 2013-07-02 | Release date: | 2013-08-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR). J.Med.Chem., 56, 2013
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4LGB
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![BU of 4lgb by Molmil](/molmil-images/mine/4lgb) | ABA-mimicking ligand N-(1-METHYL-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-6-YL)-1-(4-METHYLPHENYL)METHANESULFONAMIDE in complex with ABA receptor PYL2 and PP2C HAB1 | Descriptor: | Abscisic acid receptor PYL2, MAGNESIUM ION, N-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-1-(4-methylphenyl)methanesulfonamide, ... | Authors: | Zhou, X.E, Gao, M, Liu, X, Zhang, Y, Xue, X, Melcher, K, Gao, P, Wang, F, Zeng, L, Zhao, Y, Zhao, Y, Deng, P, Zhong, D, Zhu, J.-K, Xu, Y, Xu, H.E. | Deposit date: | 2013-06-27 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants. Cell Res., 23, 2013
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4M60
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![BU of 4m60 by Molmil](/molmil-images/mine/4m60) | Crystal structure of macrolide glycosyltransferases OleD | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Oleandomycin glycosyltransferase, SODIUM ION | Authors: | Olmos Jr, J.L, Martinez III, E, Wang, F, Helmich, K.E, Singh, S, Xu, W, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2013-08-08 | Release date: | 2013-09-04 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Crystal structure of macrolide glycosyltransferases OleD To be Published
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4MS1
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![BU of 4ms1 by Molmil](/molmil-images/mine/4ms1) | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist CGP46381 | Descriptor: | (S)-(3-aminopropyl)(cyclohexylmethyl)phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | Deposit date: | 2013-09-18 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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4MR9
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![BU of 4mr9 by Molmil](/molmil-images/mine/4mr9) | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist SCH50911 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ... | Authors: | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | Deposit date: | 2013-09-17 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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4MS4
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![BU of 4ms4 by Molmil](/molmil-images/mine/4ms4) | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the agonist baclofen | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ... | Authors: | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | Deposit date: | 2013-09-18 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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4MR7
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![BU of 4mr7 by Molmil](/molmil-images/mine/4mr7) | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist CGP54626 | Descriptor: | (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | Authors: | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | Deposit date: | 2013-09-17 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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4MR8
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![BU of 4mr8 by Molmil](/molmil-images/mine/4mr8) | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist CGP35348 | Descriptor: | (S)-(3-aminopropyl)(diethoxymethyl)phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | Deposit date: | 2013-09-17 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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4MS3
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![BU of 4ms3 by Molmil](/molmil-images/mine/4ms3) | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the endogenous agonist GABA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid type B receptor subunit 1, ... | Authors: | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | Deposit date: | 2013-09-18 | Release date: | 2013-12-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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4M6B
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![BU of 4m6b by Molmil](/molmil-images/mine/4m6b) | Crystal structure of yeast Swr1-Z domain in complex with H2A.Z-H2B dimer | Descriptor: | Chimera protein of Histone H2B.1 and Histone H2A.Z, Helicase SWR1 | Authors: | Hong, J.J, Feng, H.Q, Wang, F, Ranjan, A, Chen, J.H, Jiang, J.S, Girlando, R, Xiao, T.S, Wu, C, Bai, Y.W. | Deposit date: | 2013-08-09 | Release date: | 2014-02-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The Catalytic Subunit of the SWR1 Remodeler Is a Histone Chaperone for the H2A.Z-H2B Dimer. Mol.Cell, 53, 2014
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4MQF
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![BU of 4mqf by Molmil](/molmil-images/mine/4mqf) | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist 2-hydroxysaclofen | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxysaclofen, Gamma-aminobutyric acid type B receptor subunit 1, ... | Authors: | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | Deposit date: | 2013-09-16 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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4MQE
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![BU of 4mqe by Molmil](/molmil-images/mine/4mqe) | Crystal structure of the extracellular domain of human GABA(B) receptor in the apo form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ... | Authors: | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | Deposit date: | 2013-09-16 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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5YOX
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![BU of 5yox by Molmil](/molmil-images/mine/5yox) | HD domain-containing protein YGK1(YGL101W) | Descriptor: | HD domain-containing protein YGL101W, ZINC ION | Authors: | Yang, J, Wang, F, Gao, Z, Zhou, K, Liu, Q. | Deposit date: | 2017-10-31 | Release date: | 2018-11-21 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | HD domain-containing protein YGK1(YGL101W) To Be Published
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5W5F
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![BU of 5w5f by Molmil](/molmil-images/mine/5w5f) | Cryo-EM structure of the T4 tail tube | Descriptor: | Tail tube protein gp19 | Authors: | Zheng, W, Wang, F, Taylor, N.M, Guerrero-Ferreira, R.C, Leiman, P.G, Egelman, E.H. | Deposit date: | 2017-06-15 | Release date: | 2017-08-16 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Refined Cryo-EM Structure of the T4 Tail Tube: Exploring the Lowest Dose Limit. Structure, 25, 2017
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2HKO
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![BU of 2hko by Molmil](/molmil-images/mine/2hko) | Crystal structure of LSD1 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1 | Authors: | Chen, Y, Yang, Y.T, Wang, F, Yanane, K, Zhang, Y, Lei, M. | Deposit date: | 2006-07-05 | Release date: | 2006-08-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of human histone lysine-specific demethylase 1 (LSD1). Proc.Natl.Acad.Sci.Usa, 103, 2006
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7L5W
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![BU of 7l5w by Molmil](/molmil-images/mine/7l5w) | p97-R155H mutant dodecamer I | Descriptor: | Transitional endoplasmic reticulum ATPase | Authors: | Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. | Deposit date: | 2020-12-23 | Release date: | 2021-08-04 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
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7L5X
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![BU of 7l5x by Molmil](/molmil-images/mine/7l5x) | p97-R155H mutant dodecamer II | Descriptor: | Transitional endoplasmic reticulum ATPase | Authors: | Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. | Deposit date: | 2020-12-23 | Release date: | 2021-08-04 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
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7JR9
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![BU of 7jr9 by Molmil](/molmil-images/mine/7jr9) | Chlamydomonas reinhardtii radial spoke minimal head complex | Descriptor: | Flagellar radial spoke protein 10, Flagellar radial spoke protein 4, Flagellar radial spoke protein 6, ... | Authors: | Grossman-Haham, I, Coudray, N, Yu, Z, Wang, F, Bhabha, G, Vale, R.D. | Deposit date: | 2020-08-11 | Release date: | 2020-12-16 | Last modified: | 2021-01-27 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structure of the radial spoke head and insights into its role in mechanoregulation of ciliary beating. Nat.Struct.Mol.Biol., 28, 2021
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7JRJ
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![BU of 7jrj by Molmil](/molmil-images/mine/7jrj) | Chlamydomonas reinhardtii radial spoke head and neck (recombinant) | Descriptor: | Flagellar radial spoke protein 1, Flagellar radial spoke protein 10, Flagellar radial spoke protein 2, ... | Authors: | Grossman-Haham, I, Coudray, N, Yu, Z, Wang, F, Zhang, N, Bhabha, G, Vale, R.D. | Deposit date: | 2020-08-12 | Release date: | 2020-12-16 | Last modified: | 2021-01-27 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Structure of the radial spoke head and insights into its role in mechanoregulation of ciliary beating. Nat.Struct.Mol.Biol., 28, 2021
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8J2K
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![BU of 8j2k by Molmil](/molmil-images/mine/8j2k) | Crystal structure of a bright green fluorescent protein (StayGold) with double mutation (N137A, Q140S) in jellyfish Cytaeis uchidae from Biortus | Descriptor: | 1,2-ETHANEDIOL, StayGold(N137A, Q140S) | Authors: | Wu, J, Wang, F, Gui, W, Cheng, W, Yang, Y. | Deposit date: | 2023-04-14 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus To Be Published
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8J2J
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![BU of 8j2j by Molmil](/molmil-images/mine/8j2j) | Crystal structure of a bright green fluorescent protein (StayGold) with single mutation (Y187F) in jellyfish Cytaeis uchidae from Biortus | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, StayGold(Y187F) | Authors: | Wu, J, Wang, F, Gui, W, Cheng, W, Yang, Y. | Deposit date: | 2023-04-14 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus To Be Published
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8J2I
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![BU of 8j2i by Molmil](/molmil-images/mine/8j2i) | Crystal structure of a bright green fluorescent protein (StayGold) with single mutation (Q140S) in jellyfish Cytaeis uchidae from Biortus | Descriptor: | 1,2-ETHANEDIOL, StayGold(Q140S) | Authors: | Wu, J, Wang, F, Gui, W, Cheng, W, Yang, Y. | Deposit date: | 2023-04-14 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus To Be Published
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8J3J
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![BU of 8j3j by Molmil](/molmil-images/mine/8j3j) | Crystal structure of a bright green fluorescent protein (StayGold) with double mutations (Q140S, Y187F) in jellyfish Cytaeis uchidae from Biortus | Descriptor: | 1,2-ETHANEDIOL, StayGold(Q140S, Y187F) | Authors: | Wu, J, Wang, F, Gui, W, Cheng, W, Yang, Y. | Deposit date: | 2023-04-17 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus To Be Published
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8J2L
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![BU of 8j2l by Molmil](/molmil-images/mine/8j2l) | Crystal structure of a bright green fluorescent protein (StayGold) with double mutations (N137A, Y187F) in jellyfish Cytaeis uchidae from Biortus | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, SODIUM ION, ... | Authors: | Wu, J, Wang, F, Gui, W, Cheng, W, Yang, Y. | Deposit date: | 2023-04-14 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus To Be Published
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