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PDB: 447 results

6U8B
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Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Descriptor: 3-{[(5-bromo-2-methoxyphenyl)sulfonyl]amino}-5-chloro-2-hydroxybenzoic acid, WD repeat-containing protein 5
Authors:Zhao, B, Wang, F.
Deposit date:2019-09-04
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.261 Å)
Cite:Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
6U6W
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Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Descriptor: 5-bromo-N-(5-chloro-2-hydroxyphenyl)-2-methoxybenzene-1-sulfonamide, WD repeat-containing protein 5
Authors:Zhao, B, Wang, F.
Deposit date:2019-08-30
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
3K57
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Crystal structure of E.coli Pol II-normal DNA-dATP ternary complex
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*G*TP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*G)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
4MRM
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Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist phaclofen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-17
Release date:2013-12-11
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MQF
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Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist 2-hydroxysaclofen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxysaclofen, Gamma-aminobutyric acid type B receptor subunit 1, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-16
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MQE
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Crystal structure of the extracellular domain of human GABA(B) receptor in the apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-16
Release date:2013-12-11
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MR7
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Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist CGP54626
Descriptor: (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-17
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MR8
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Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist CGP35348
Descriptor: (S)-(3-aminopropyl)(diethoxymethyl)phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-17
Release date:2013-12-11
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MS3
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Crystal structure of the extracellular domain of human GABA(B) receptor bound to the endogenous agonist GABA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid type B receptor subunit 1, ...
Authors:Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
Deposit date:2013-09-18
Release date:2013-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
7R7S
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BU of 7r7s by Molmil
p47-bound p97-R155H mutant with ATPgammaS
Descriptor: NSFL1 cofactor p47, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
Authors:Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L.
Deposit date:2021-06-25
Release date:2021-08-04
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.23 Å)
Cite:Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes.
Int J Mol Sci, 22, 2021
7R7T
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p47-bound p97-R155H mutant with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, NSFL1 cofactor p47, Transitional endoplasmic reticulum ATPase
Authors:Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L.
Deposit date:2021-06-25
Release date:2021-08-04
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes.
Int J Mol Sci, 22, 2021
7R7U
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BU of 7r7u by Molmil
D1 and D2 domain structure of the p97(R155H)-p47 complex
Descriptor: Transitional endoplasmic reticulum ATPase
Authors:Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Poh, Y.-P, Chou, T.-F, Chiu, P.-L.
Deposit date:2021-06-25
Release date:2021-08-04
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes.
Int J Mol Sci, 22, 2021
9BJN
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BU of 9bjn by Molmil
Cryo-EM of Azo-ffspy fiber
Descriptor: D-peptide ffspy
Authors:Zia, A, Guo, J, Xu, B, Wang, F.
Deposit date:2024-04-25
Release date:2024-09-18
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cell-Free Nonequilibrium Assembly for Hierarchical Protein/Peptide Nanopillars.
J.Am.Chem.Soc., 146, 2024
9BJO
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BU of 9bjo by Molmil
Cryo-EM of Azo-ffsy fiber
Descriptor: D-peptide ffsy
Authors:Zia, A, Guo, J, Xu, B, Wang, F.
Deposit date:2024-04-25
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cell-Free Nonequilibrium Assembly for Hierarchical Protein/Peptide Nanopillars.
J.Am.Chem.Soc., 146, 2024
4QY1
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BU of 4qy1 by Molmil
Structure of H10 from human-infecting H10N8 in complex with avian receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
7Q5A
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BU of 7q5a by Molmil
Lanreotide nanotube
Descriptor: Lanreotide
Authors:Pieri, L, Wang, F, Arteni, A.A, Bressanelli, S, Egelman, E.H, Paternostre, M.
Deposit date:2021-11-03
Release date:2022-04-06
Method:ELECTRON MICROSCOPY (2.46 Å)
Cite:Atomic structure of Lanreotide nanotubes revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
5JHG
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BU of 5jhg by Molmil
Crystal structure of the complex between the human RhoA and the DH/PH domain of human ARHGEF11
Descriptor: GLYCEROL, Rho guanine nucleotide exchange factor 11, Transforming protein RhoA
Authors:Wang, R, Chen, Q, Zhang, H, Yan, Z, Li, J, Miao, L, Wang, F.
Deposit date:2016-04-21
Release date:2017-04-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and ARHGEF11
To Be Published
3JCO
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BU of 3jco by Molmil
Structure of yeast 26S proteasome in M1 state derived from Titan dataset
Descriptor: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
Authors:Luan, B, Huang, X.L, Wu, J.P, Shi, Y.G, Wang, F.
Deposit date:2016-01-06
Release date:2016-06-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structure of an endogenous yeast 26S proteasome reveals two major conformational states.
Proc.Natl.Acad.Sci.USA, 113, 2016
4KON
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BU of 4kon by Molmil
The structure of hemagglutinin from avian-origin H7N9 influenza virus in complex with human receptor analog 6'SLNLN (NeuAcα2-6Galβ1-4GlcNAcβ1-3Galβ1-4Glc)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
Authors:Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F.
Deposit date:2013-05-12
Release date:2013-11-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses.
Science, 342, 2013
4LKK
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BU of 4lkk by Molmil
The structure of hemagglutinin L226Q mutant (H3 numbering) from a avian-origin H7N9 influenza virus (A/Anhui/1/2013) in complex with human receptor analog 6'SLNLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, hemagglutinin
Authors:Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F.
Deposit date:2013-07-07
Release date:2013-11-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.491 Å)
Cite:Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses
Science, 342, 2013
4KOL
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BU of 4kol by Molmil
The structure of hemagglutinin from avian-origin H7N9 influenza virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2
Authors:Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F.
Deposit date:2013-05-12
Release date:2013-11-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses.
Science, 342, 2013
4LKG
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BU of 4lkg by Molmil
The structure of hemagglutinin from a avian-origin H7N9 influenza virus (A/Shanghai/1/2013) in complex with avian receptor analog 3'SLNLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F.
Deposit date:2013-07-07
Release date:2013-11-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.994 Å)
Cite:Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses
Science, 342, 2013
4LKJ
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BU of 4lkj by Molmil
The structure of hemagglutinin L226Q mutant (H3 numbering) from a avian-origin H7N9 influenza virus (A/Anhui/1/2013) in complex with avian receptor analog 3'SLNLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
Authors:Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F.
Deposit date:2013-07-07
Release date:2013-11-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses
Science, 342, 2013
4LKH
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BU of 4lkh by Molmil
The structure of hemagglutinin from a avian-origin H7N9 influenza virus (A/Shanghai/1/2013) in complex with human receptor analog 6'SLNLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, hemagglutinin
Authors:Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F.
Deposit date:2013-07-07
Release date:2013-11-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.099 Å)
Cite:Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses
Science, 342, 2013
4LCX
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The structure of hemagglutinin from avian-origin H7N9 influenza virus (A/Shanghai/1/2013)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2
Authors:Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F.
Deposit date:2013-06-24
Release date:2013-11-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.094 Å)
Cite:Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses.
Science, 342, 2013

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