5KLO
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![BU of 5klo by Molmil](/molmil-images/mine/5klo) | Crystal structure of thioacyl intermediate in 2-aminomuconate 6-semialdehyde dehydrogenase N169A | Descriptor: | (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoic acid, 2-aminomuconate 6-semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Yang, Y, Davis, I, Ha, U, Wang, Y, Shin, I, Liu, A. | Deposit date: | 2016-06-24 | Release date: | 2016-11-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | A Pitcher-and-Catcher Mechanism Drives Endogenous Substrate Isomerization by a Dehydrogenase in Kynurenine Metabolism. J.Biol.Chem., 291, 2016
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5KLM
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![BU of 5klm by Molmil](/molmil-images/mine/5klm) | Crystal structure of 2-hydroxymuconate-6-semialdehyde derived intermediate in NAD(+)-bound 2-aminomuconate 6-semialdehyde dehydrogenase N169D | Descriptor: | 2-aminomuconate 6-semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION | Authors: | Yang, Y, Davis, I, Ha, U, Wang, Y, Shin, I, Liu, A. | Deposit date: | 2016-06-24 | Release date: | 2016-11-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | A Pitcher-and-Catcher Mechanism Drives Endogenous Substrate Isomerization by a Dehydrogenase in Kynurenine Metabolism. J.Biol.Chem., 291, 2016
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4H75
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![BU of 4h75 by Molmil](/molmil-images/mine/4h75) | Crystal structure of human Spindlin1 in complex with a histone H3K4(me3) peptide | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Histone H3, ... | Authors: | Yang, N, Wang, W, Wang, Y, Wang, M, Zhao, Q, Rao, Z, Zhu, B, Xu, R.M. | Deposit date: | 2012-09-20 | Release date: | 2012-10-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.098 Å) | Cite: | Distinct mode of methylated lysine-4 of histone H3 recognition by tandem tudor-like domains of Spindlin1. Proc.Natl.Acad.Sci.USA, 109, 2012
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2QTU
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![BU of 2qtu by Molmil](/molmil-images/mine/2qtu) | Estrogen receptor beta ligand-binding domain complexed to a benzopyran ligand | Descriptor: | (3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol, Estrogen receptor beta | Authors: | Richardson, T.I, Dodge, J.A, Wang, Y, Durbin, J.D, Krishnan, V, Norman, B.H. | Deposit date: | 2007-08-02 | Release date: | 2007-10-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 5: Combined A- and C-ring structure-activity relationship studies. Bioorg.Med.Chem.Lett., 17, 2007
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1QJL
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![BU of 1qjl by Molmil](/molmil-images/mine/1qjl) | METALLOTHIONEIN MTA FROM SEA URCHIN (BETA DOMAIN) | Descriptor: | CADMIUM ION, METALLOTHIONEIN | Authors: | Riek, R, Precheur, B, Wang, Y, Mackay, E.A, Wider, G, Guntert, P, Liu, A, Kaegi, J.H.R, Wuthrich, K. | Deposit date: | 1999-06-24 | Release date: | 1999-08-31 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR structure of the sea urchin (Strongylocentrotus purpuratus) metallothionein MTA. J. Mol. Biol., 291, 1999
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1QJK
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![BU of 1qjk by Molmil](/molmil-images/mine/1qjk) | Metallothionein MTA from sea urchin (alpha domain) | Descriptor: | CADMIUM ION, METALLOTHIONEIN | Authors: | Riek, R, Precheur, B, Wang, Y, Mackay, E.A, Wider, G, Guntert, P, Liu, A, Kaegi, J.H.R, Wuthrich, K. | Deposit date: | 1999-06-24 | Release date: | 1999-08-31 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR structure of the sea urchin (Strongylocentrotus purpuratus) metallothionein MTA. J. Mol. Biol., 291, 1999
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6LP2
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![BU of 6lp2 by Molmil](/molmil-images/mine/6lp2) | Structure of Lpg2148/UBE2N-Ub complex | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 N, Uncharacterized protein lpg2148 | Authors: | Feng, Y, Wang, Y, Huang, Y, Li, D. | Deposit date: | 2020-01-08 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.479 Å) | Cite: | Structure of Lpg2148/UBE2N-Ub complex To Be Published
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6LY6
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![BU of 6ly6 by Molmil](/molmil-images/mine/6ly6) | PylRS C-terminus domain mutant bound with 3-(1-Naphthyl)-L-alanine and AMPNP | Descriptor: | MAGNESIUM ION, NAPHTHALEN-2-YL-3-ALANINE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Weng, J.H, Tsai, M.D, Wang, Y.S. | Deposit date: | 2020-02-13 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5001328 Å) | Cite: | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues. Biochemistry, 59, 2020
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6LY3
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![BU of 6ly3 by Molmil](/molmil-images/mine/6ly3) | PylRS C-terminus domain mutant bound with 3-Benzothienyl-L-alanine and AMPNP | Descriptor: | 3-(1-benzothiophen-3-yl)-L-alanine, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Weng, J.H, Tsai, M.D, Wang, Y.S. | Deposit date: | 2020-02-13 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.89590144 Å) | Cite: | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues. Biochemistry, 59, 2020
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6LYA
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![BU of 6lya by Molmil](/molmil-images/mine/6lya) | PylRS C-terminus domain mutant bound with 1-Methyl-L-tryptophan and AMPNP | Descriptor: | 1,2-ETHANEDIOL, 1-Methyl-L-tryptophan, MAGNESIUM ION, ... | Authors: | Weng, J.H, Tsai, M.D, Wang, Y.S. | Deposit date: | 2020-02-13 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.590702 Å) | Cite: | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues. Biochemistry, 59, 2020
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6LYB
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![BU of 6lyb by Molmil](/molmil-images/mine/6lyb) | PylRS C-terminus domain mutant in complex with 3-Benzothienyl-D-alanine and AMPNP | Descriptor: | (2R)-2-azanyl-3-(1-benzothiophen-3-yl)propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Weng, J.H, Tsai, M.D, Wang, Y.S. | Deposit date: | 2020-02-13 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.90366471 Å) | Cite: | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues. Biochemistry, 59, 2020
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1ONB
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![BU of 1onb by Molmil](/molmil-images/mine/1onb) | |
6LY7
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![BU of 6ly7 by Molmil](/molmil-images/mine/6ly7) | PylRS C-terminus domain mutant bound with 1-Formyl-L-tryptophan and AMPNP | Descriptor: | MAGNESIUM ION, N1-FORMYL-TRYPTOPHAN, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Weng, J.H, Tsai, M.D, Wang, Y.S. | Deposit date: | 2020-02-13 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.09447265 Å) | Cite: | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues. Biochemistry, 59, 2020
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3NYL
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![BU of 3nyl by Molmil](/molmil-images/mine/3nyl) | The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain | Descriptor: | Amyloid beta (A4) protein (Peptidase nexin-II, Alzheimer disease), isoform CRA_b | Authors: | Ha, Y, Hu, J, Lee, S, Liu, X, Wang, Y. | Deposit date: | 2010-07-15 | Release date: | 2011-07-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain. Mol.Cell, 15, 2004
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6LW4
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![BU of 6lw4 by Molmil](/molmil-images/mine/6lw4) | |
4BGG
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![BU of 4bgg by Molmil](/molmil-images/mine/4bgg) | Crystal structure of the ACVR1 kinase in complex with LDN-213844 | Descriptor: | 1,2-ETHANEDIOL, 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine, ACTIVIN RECEPTOR TYPE-1, ... | Authors: | Sanvitale, C, Canning, P, Cooper, C, Wang, Y, Mohedas, A.H, Choi, S, Yu, P.B, Cuny, G.D, Nowak, R, Coutandin, D, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | Deposit date: | 2013-03-26 | Release date: | 2013-04-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Structure-Activity Relationship of 3,5-Diaryl-2-Aminopyridine Alk2 Inhibitors Reveals Unaltered Binding Affinity for Fibrodysplasia Ossificans Progressiva Causing Mutants. J.Med.Chem., 57, 2014
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3PMR
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![BU of 3pmr by Molmil](/molmil-images/mine/3pmr) | Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1 | Descriptor: | Amyloid-like protein 1, PHOSPHATE ION | Authors: | Lee, S, Xue, Y, Hu, J, Wang, Y, Liu, X, Demeler, B, Ha, Y. | Deposit date: | 2010-11-17 | Release date: | 2011-06-01 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization. Biochemistry, 50, 2011
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1KGU
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![BU of 1kgu by Molmil](/molmil-images/mine/1kgu) | THREE DIMENSIONAL STRUCTURE ANALYSIS OF THE R337A VARIANT OF HUMAN PANCREATIC ALPHA-AMYLASE | Descriptor: | ALPHA-AMYLASE, PANCREATIC, CALCIUM ION | Authors: | Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G. | Deposit date: | 2001-11-28 | Release date: | 2002-01-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase. Biochemistry, 41, 2002
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5GNF
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![BU of 5gnf by Molmil](/molmil-images/mine/5gnf) | Crystal structure of anti-CRISPR protein AcrF3 | Descriptor: | CALCIUM ION, Uncharacterized protein AcrF3 | Authors: | Wang, J, Wang, Y. | Deposit date: | 2016-07-20 | Release date: | 2016-09-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses Cell Res., 26, 2016
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1A52
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![BU of 1a52 by Molmil](/molmil-images/mine/1a52) | |
4DRQ
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![BU of 4drq by Molmil](/molmil-images/mine/4drq) | Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52: Complex of FKBP51 with 2-(3-((R)-1-((S)-1-(3,5-dichlorophenylsulfonyl)piperidine-2-carbonyloxy)-3-(3,4-dimethoxy -phenyl)propyl)phenoxy)acetic acid | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP5, {3-[(1S)-1-[({(2S)-1-[(3,5-dichlorophenyl)sulfonyl]piperidin-2-yl}carbonyl)oxy]-3-(3,4-dimethoxyphenyl)propyl]phenoxy}acetic acid | Authors: | Gopalakrishnan, R, Kozany, C, Wang, Y, Hoogeland, B, Bracher, A, Hausch, F, Schneider, S. | Deposit date: | 2012-02-17 | Release date: | 2012-04-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52. J.Med.Chem., 55, 2012
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5GQH
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![BU of 5gqh by Molmil](/molmil-images/mine/5gqh) | Cryo-EM structure of PaeCas3-AcrF3 complex | Descriptor: | CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST, anti-CRISPR protein 3 | Authors: | Zhang, X, Ma, J, Wang, Y, Wang, J. | Deposit date: | 2016-08-07 | Release date: | 2016-09-21 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses Cell Res., 26, 2016
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4BT0
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![BU of 4bt0 by Molmil](/molmil-images/mine/4bt0) | MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, TRANSCRIPTIONAL REGULATOR | Authors: | Mizuno, N, Dramicanin, M, Mizuuchi, M, Adam, J, Wang, Y, Han, Y.W, Yang, W, Steven, A.C, Mizuuchi, K, Ramon-Maiques, S. | Deposit date: | 2013-06-12 | Release date: | 2013-07-03 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (17 Å) | Cite: | Mub is an Aaa+ ATPase that Forms Helical Filaments to Control Target Selection for DNA Transposition. Proc.Natl.Acad.Sci.USA, 110, 2013
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1BSI
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![BU of 1bsi by Molmil](/molmil-images/mine/1bsi) | HUMAN PANCREATIC ALPHA-AMYLASE FROM PICHIA PASTORIS, GLYCOSYLATED PROTEIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, CALCIUM ION, ... | Authors: | Rydberg, E.H, Sidhu, G, Vo, H.C, Hewitt, J, Cote, H.C.F, Wang, Y, Numao, S, Macgillivray, R.T.A, Overall, C.M, Brayer, G.D, Withers, S.G. | Deposit date: | 1998-08-28 | Release date: | 1999-05-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Cloning, mutagenesis, and structural analysis of human pancreatic alpha-amylase expressed in Pichia pastoris. Protein Sci., 8, 1999
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1KGX
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![BU of 1kgx by Molmil](/molmil-images/mine/1kgx) | Three Dimensional Structure Analysis of the R195Q Variant of Human Pancreatic Alpha Amylase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ... | Authors: | Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G. | Deposit date: | 2001-11-28 | Release date: | 2002-01-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase. Biochemistry, 41, 2002
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