4KZM
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![BU of 4kzm by Molmil](/molmil-images/mine/4kzm) | Crystal Structure of TR3 LBD S553A Mutant | 分子名称: | GLYCEROL, Nuclear receptor subfamily 4 group A member 1 | 著者 | Li, F, Zhang, Q, Li, A, Tian, X, Cai, Q, Wang, W, Wang, Y, Chen, H, Xing, Y, Wu, Q, Lin, T. | 登録日 | 2013-05-30 | 公開日 | 2013-12-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway. Nat.Chem.Biol., 10, 2014
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2ZEE
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![BU of 2zee by Molmil](/molmil-images/mine/2zee) | Crystal structure of the human glutaminyl cyclase mutant S160G at 1.99 angstrom resolution | 分子名称: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | 著者 | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | 登録日 | 2007-12-12 | 公開日 | 2008-04-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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2ZEN
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![BU of 2zen by Molmil](/molmil-images/mine/2zen) | Crystal structure of the human glutaminyl cyclase mutant D305A at 1.78 angstrom resolution | 分子名称: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | 著者 | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | 登録日 | 2007-12-13 | 公開日 | 2008-04-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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5XAF
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![BU of 5xaf by Molmil](/molmil-images/mine/5xaf) | Crystal structure of tubulin-stathmin-TTL-Compound Z1 complex | 分子名称: | (3S,4R)-4-(3-hydroxy-4-methoxyphenyl)-3-methyl-1-(3,4,5-trimethoxyphenyl)azetidin-2-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Zhang, H, Luo, C, Wang, Y. | 登録日 | 2017-03-12 | 公開日 | 2017-12-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.551 Å) | 主引用文献 | Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents Eur J Med Chem, 144, 2017
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1ZOI
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![BU of 1zoi by Molmil](/molmil-images/mine/1zoi) | Crystal Structure of a Stereoselective Esterase from Pseudomonas putida IFO12996 | 分子名称: | esterase | 著者 | Elmi, F, Lee, H.T, Huang, J.Y, Hsieh, Y.C, Wang, Y.L, Chen, Y.J, Shaw, S.Y, Chen, C.J. | 登録日 | 2005-05-13 | 公開日 | 2006-05-02 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Stereoselective esterase from Pseudomonas putida IFO12996 reveals alpha/beta hydrolase folds for D-beta-acetylthioisobutyric acid synthesis J.Bacteriol., 187, 2005
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6P8D
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![BU of 6p8d by Molmil](/molmil-images/mine/6p8d) | |
7DQ9
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![BU of 7dq9 by Molmil](/molmil-images/mine/7dq9) | |
5XT0
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![BU of 5xt0 by Molmil](/molmil-images/mine/5xt0) | Crystal Structure of Transketolase in complex with TPP intermediate VIII from Pichia Stipitis | 分子名称: | 2-C-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium-2-yl}-6-O-phosphono-D-glucitol, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Li, T.L, Hsu, N.S, Wang, Y.L. | 登録日 | 2017-06-16 | 公開日 | 2018-06-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions. Chembiochem, 19, 2018
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6PEC
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![BU of 6pec by Molmil](/molmil-images/mine/6pec) | |
6PEF
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![BU of 6pef by Molmil](/molmil-images/mine/6pef) | |
6IIL
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![BU of 6iil by Molmil](/molmil-images/mine/6iil) | USP14 catalytic domain bind to IU1-47 | 分子名称: | 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(piperidin-1-yl)ethan-1-one, Ubiquitin carboxyl-terminal hydrolase 14 | 著者 | Mei, Z.Q, Wang, Y.W, Wang, F, Wang, J.W, He, W, Ding, S, Li, J.W. | 登録日 | 2018-10-07 | 公開日 | 2018-12-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade. Cell Res., 28, 2018
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8IFG
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![BU of 8ifg by Molmil](/molmil-images/mine/8ifg) | Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe | 分子名称: | Chromatin modification-related protein eaf3, Cph1, Cph2, ... | 著者 | Zhang, H.Q, Wang, X, Wang, Y.N, Liu, S.M, Zhang, Y, Xu, K, Ji, L.T, Kornberg, R.D. | 登録日 | 2023-02-17 | 公開日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Class I histone deacetylase complex: Structure and functional correlates. Proc Natl Acad Sci U S A, 120, 2023
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5XPS
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![BU of 5xps by Molmil](/molmil-images/mine/5xps) | Crystal Structure of Transketolase in complex with erythrose-4-phosphate from Pichia Stipitis | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, ERYTHOSE-4-PHOSPHATE, ... | 著者 | Li, T.L, Hsu, N.S, Wang, Y.L. | 登録日 | 2017-06-04 | 公開日 | 2018-06-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions. Chembiochem, 19, 2018
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5XTX
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![BU of 5xtx by Molmil](/molmil-images/mine/5xtx) | Crystal Structure of Transketolase in complex with TPP intermediate VII from Pichia Stipitis | 分子名称: | 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methylidene-2-[(2S,3S,4R,5R)-1,2,3,4,5-pentakis(oxidanyl)-6-phosphonooxy-hexan-2-yl]-1,3-thiazolidin-5-yl]ethyl phosphono hydrogen phosphate, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Li, T.L, Hsu, N.S, Wang, Y.L. | 登録日 | 2017-06-21 | 公開日 | 2018-06-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.049 Å) | 主引用文献 | Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions. Chembiochem, 19, 2018
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6PDS
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![BU of 6pds by Molmil](/molmil-images/mine/6pds) | Vaccine-elicited NHP FP-targeting antibody 0PV-a.04 in complex with HIV fusion peptide (residue 512-519) | 分子名称: | HIV-1 fusion peptide residue 512-519, SULFATE ION, antibody 0PV-a.04 heavy chain, ... | 著者 | Xu, K, Liu, K, Wang, Y, Kwong, P.D. | 登録日 | 2019-06-19 | 公開日 | 2020-06-24 | 実験手法 | X-RAY DIFFRACTION (1.893 Å) | 主引用文献 | Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies To Be Published
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8IAG
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5XAG
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![BU of 5xag by Molmil](/molmil-images/mine/5xag) | Crystal structure of tubulin-stathmin-TTL-Compound Z2 complex | 分子名称: | (3~{R},4~{R})-3-(hydroxymethyl)-4-(4-methoxy-3-oxidanyl-phenyl)-1-(3,4,5-trimethoxyphenyl)azetidin-2-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Zhang, H, Luo, C, Wang, Y. | 登録日 | 2017-03-12 | 公開日 | 2018-01-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents Eur J Med Chem, 144, 2017
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5XU9
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![BU of 5xu9 by Molmil](/molmil-images/mine/5xu9) | Crystal Structure of Transketolase in complex with TPP intermediate IX and gauche form erythrose-4-phosphate from Pichia Stipitis | 分子名称: | 2-[(2E)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[1,2-bis(oxidanyl)ethylidene]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Li, T.L, Hsu, N.S, Wang, Y.L. | 登録日 | 2017-06-22 | 公開日 | 2018-06-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.166 Å) | 主引用文献 | Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions. Chembiochem, 19, 2018
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4BS1
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![BU of 4bs1 by Molmil](/molmil-images/mine/4bs1) | MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, TRANSCRIPTIONAL REGULATOR (NTRC FAMILY) | 著者 | Mizuno, N, Dramicanin, M, Mizuuchi, M, Adam, J, Wang, Y, Han, Y.W, Yang, W, Steven, A.C, Mizuuchi, K, Ramon-Maiques, S. | 登録日 | 2013-06-06 | 公開日 | 2013-07-03 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (18 Å) | 主引用文献 | Mub is an Aaa+ ATPase that Forms Helical Filaments to Control Target Selection for DNA Transposition. Proc.Natl.Acad.Sci.USA, 110, 2013
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7PEM
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![BU of 7pem by Molmil](/molmil-images/mine/7pem) | Cryo-EM structure of phophorylated Drs2p-Cdc50p in a PS and ATP-bound E2P state | 分子名称: | (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Timcenko, M, Wang, Y, Lyons, J.A, Nissen, P, Lindorff-Larsen, K. | 登録日 | 2021-08-10 | 公開日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Substrate Transport and Specificity in a Phospholipid Flippase To Be Published
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5XQK
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![BU of 5xqk by Molmil](/molmil-images/mine/5xqk) | Crystal Structure of Transketolase in complex with xylulose-5-phosphate from Pichia Stipitis | 分子名称: | 2-C-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thia zol-3-ium-2-yl}-5-O-phosphono-D-xylitol, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Li, T.L, Hsu, N.S, Wang, Y.L. | 登録日 | 2017-06-07 | 公開日 | 2018-06-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions. Chembiochem, 19, 2018
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6PDR
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![BU of 6pdr by Molmil](/molmil-images/mine/6pdr) | |
5XQA
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![BU of 5xqa by Molmil](/molmil-images/mine/5xqa) | Crystal Structure of Transketolase in complex with ribose-5-phosphate from Pichia Stipitis | 分子名称: | 5-O-phosphono-alpha-D-ribofuranose, CALCIUM ION, THIAMINE DIPHOSPHATE, ... | 著者 | Li, T.L, Hsu, N.S, Wang, Y.L. | 登録日 | 2017-06-06 | 公開日 | 2018-06-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions. Chembiochem, 19, 2018
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5XRV
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![BU of 5xrv by Molmil](/molmil-images/mine/5xrv) | Crystal Structure of Transketolase in complex with TPP_V and fructose-6-phosphate from Pichia Stipitis | 分子名称: | 2-[(5S)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methylidene-1,3-thiazolidin-5-yl]ethyl phosphono hydrogen phosphate, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Li, T.L, Hsu, N.S, Wang, Y.L. | 登録日 | 2017-06-09 | 公開日 | 2018-06-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions. Chembiochem, 19, 2018
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6PDU
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![BU of 6pdu by Molmil](/molmil-images/mine/6pdu) | Vaccine-elicited NHP FP-targeting antibody 13N024-a.01 in complex with HIV fusion peptide (residue 512-519) | 分子名称: | HIV-1 fusion peptide residue 512-519, antibody 13N024-a.01, heavy chain, ... | 著者 | Xu, K, Liu, K, Wang, Y, Kwong, P.D. | 登録日 | 2019-06-19 | 公開日 | 2020-06-24 | 実験手法 | X-RAY DIFFRACTION (1.953 Å) | 主引用文献 | Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies To Be Published
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