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6PEF

Vaccine-elicited NHP FP-targeting antibody DF2F-a.01 in complex with HIV fusion peptide (residue 512-519)

Summary for 6PEF
Entry DOI10.2210/pdb6pef/pdb
Descriptorantibody DF2F-a.01 heavy chain, antibody DF2F-a.01 light chain, HIV fusion peptide residue 512-519, ... (4 entities in total)
Functional Keywordshiv, neutralizing, antibody, nhp, fp, fusion peptide, vaccine, immune system
Biological sourceMacaca mulatta
More
Total number of polymer chains6
Total formula weight94339.13
Authors
Xu, K.,Liu, K.,Wang, Y.,Kwong, P.D. (deposition date: 2019-06-20, release date: 2020-06-24)
Primary citationXu, K.,Liu, K.,Wang, Y.,Kwong, P.D.
Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.004 Å)
Structure validation

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