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PDB: 538 件

5VRQ
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Crystal structure of Legionella pneumophila effector AnkC
分子名称: Ankyrin repeat-containing protein
著者Kozlov, G, Wong, K, Wang, W, Skubak, P, Munoz-Escobar, J, Liu, Y, Pannu, N.S, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2017-05-11
公開日2017-11-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.205 Å)
主引用文献Ankyrin repeats as a dimerization module.
Biochem. Biophys. Res. Commun., 495, 2018
4O0Z
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BU of 4o0z by Molmil
Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase
分子名称: N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}indolizine-6-carboxamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION
著者Oh, A, Wang, W.
登録日2013-12-14
公開日2014-06-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.049 Å)
主引用文献Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase.
Chembiochem, 15, 2014
4O0R
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BU of 4o0r by Molmil
Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors
分子名称: PF-3758309, Serine/threonine-protein kinase PAK 1
著者Rouge, L, Tam, C, Wang, W.
登録日2013-12-14
公開日2014-02-12
最終更新日2019-01-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors.
J.Med.Chem., 57, 2014
7E58
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interferon-inducible anti-viral protein 2
分子名称: Guanylate-binding protein 2
著者Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T.
登録日2021-02-18
公開日2021-05-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
4O1C
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BU of 4o1c by Molmil
The crystal structures of a mutant NAMPT H191R
分子名称: 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION
著者Oh, A, Coons, M, Brillantes, B, Wang, W.
登録日2013-12-15
公開日2014-10-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.092 Å)
主引用文献Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors.
Plos One, 9, 2014
7E59
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interferon-inducible anti-viral protein truncated
分子名称: Guanylate-binding protein 5
著者Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T.
登録日2021-02-18
公開日2021-05-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
7E5A
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BU of 7e5a by Molmil
interferon-inducible anti-viral protein R356A
分子名称: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate-binding protein 5, ...
著者Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T.
登録日2021-02-18
公開日2021-05-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
4O14
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Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors
分子名称: 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION
著者Oh, A, Coons, M, Brillantes, B, Wang, W.
登録日2013-12-15
公開日2014-10-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.871 Å)
主引用文献Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors.
Plos One, 9, 2014
4O15
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The crystal structure of a mutant NAMPT (S165F) in complex with GNE-618
分子名称: 1,2-ETHANEDIOL, N-(4-{[3-(trifluoromethyl)phenyl]sulfonyl}benzyl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide, Nicotinamide phosphoribosyltransferase, ...
著者Oh, A, Coons, M, Brillantes, B, Wang, W.
登録日2013-12-15
公開日2014-10-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors.
Plos One, 9, 2014
5URV
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BU of 5urv by Molmil
Crystal structure of Frizzled 7 CRD in complex with C24 fatty acid
分子名称: (15E)-TETRACOS-15-ENOIC ACID, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Mukund, S, Nile, A.H, Stanger, K, Hannoush, R.N, Wang, W.
登録日2017-02-13
公開日2017-05-10
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5URZ
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Crystal structure of Frizzled 5 CRD in complex with BOG
分子名称: Frizzled-5, alpha-L-fucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, octyl beta-D-glucopyranoside
著者Mukund, S, Nile, A.H, Stanger, K, Hannoush, R.N, Wang, W.
登録日2017-02-13
公開日2017-05-10
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WBS
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BU of 5wbs by Molmil
Crystal structure of Frizzled-7 CRD with an inhibitor peptide Fz7-21
分子名称: Frizzled-7,inhibitor peptide Fz7-21
著者Nile, A.H, Mukund, S, Hannoush, R.N, Wang, W.
登録日2017-06-29
公開日2018-04-18
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.
Nat. Chem. Biol., 14, 2018
4NFT
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BU of 4nft by Molmil
Crystal structure of human lnkH2B-h2A.Z-Anp32e
分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member E, Histone H2B type 2-E, Histone H2A.Z
著者Shan, S, Pan, L, Mao, Z, Wang, W, Sun, J, Dong, Q, Liang, X, Ding, X, Chen, S, Dai, L, Zhang, Z, Zhu, B, Zhou, Z.
登録日2013-11-01
公開日2014-04-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z
Cell Res., 24, 2014
4O8N
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BU of 4o8n by Molmil
Crystal structure of SthAraf62A, a GH62 family alpha-L-arabinofuranosidase from Streptomyces thermoviolaceus, in the apoprotein form
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-L-arabinofuranosidase, CALCIUM ION, ...
著者Stogios, P.J, Wang, W, Xu, X, Cui, H, Master, E, Savchenko, A.
登録日2013-12-28
公開日2014-07-02
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (1.6476 Å)
主引用文献Elucidation of the molecular basis for arabinoxylan-debranching activity of a thermostable family GH62 alpha-l-arabinofuranosidase from Streptomyces thermoviolaceus.
Appl.Environ.Microbiol., 80, 2014
7EW4
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BU of 7ew4 by Molmil
Cryo-EM structure of CYM-5541-bound Sphingosine 1-phosphate receptor 3 in complex with Gi protein
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Zhao, C, Wang, W, Wang, H.L, Shao, Z.H.
登録日2021-05-24
公開日2021-09-29
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into sphingosine-1-phosphate recognition and ligand selectivity of S1PR3-Gi signaling complexes.
Cell Res., 32, 2022
7EW2
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BU of 7ew2 by Molmil
Cryo-EM structure of pFTY720-bound Sphingosine 1-phosphate receptor 3 in complex with Gi protein
分子名称: (2~{S})-2-azanyl-4-(4-octylphenyl)-2-[[oxidanyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxymethyl]butan-1-ol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhao, C, Wang, W, Wang, H.L, Shao, Z.H.
登録日2021-05-24
公開日2021-09-29
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into sphingosine-1-phosphate recognition and ligand selectivity of S1PR3-Gi signaling complexes.
Cell Res., 32, 2022
7EW3
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BU of 7ew3 by Molmil
Cryo-EM structure of S1P-bound Sphingosine 1-phosphate receptor 3 in complex with Gi protein
分子名称: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhao, C, Wang, W, Wang, H.L, Shao, Z.H.
登録日2021-05-24
公開日2021-09-29
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into sphingosine-1-phosphate recognition and ligand selectivity of S1PR3-Gi signaling complexes.
Cell Res., 32, 2022
4KNF
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BU of 4knf by Molmil
Crystal structure of a blue-light absorbing proteorhodopsin double-mutant D97N/Q105L from HOT75
分子名称: Blue-light absorbing proteorhodopsin, RETINAL
著者Ran, T, Ozorowski, G, Gao, Y, Wang, W, Luecke, H.
登録日2013-05-09
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Cross-protomer interaction with the photoactive site in oligomeric proteorhodopsin complexes.
Acta Crystallogr.,Sect.D, 69, 2013
4KLY
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BU of 4kly by Molmil
Crystal structure of a blue-light absorbing proteorhodopsin mutant D97N from HOT75
分子名称: Blue-light absorbing proteorhodopsin, RETINAL
著者Ran, T, Ozorowski, G, Gao, Y, Wang, W, Luecke, H.
登録日2013-05-07
公開日2013-06-05
最終更新日2013-10-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cross-protomer interaction with the photoactive site in oligomeric proteorhodopsin complexes.
Acta Crystallogr.,Sect.D, 69, 2013
4L4M
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BU of 4l4m by Molmil
Structural Analysis of a Phosphoribosylated Inhibitor in Complex with Human Nicotinamide Phosphoribosyltransferase
分子名称: 1,2-ETHANEDIOL, N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}imidazo[1,2-a]pyridine-7-carboxamide, Nicotinamide phosphoribosyltransferase, ...
著者Oh, A, Ho, Y, Zak, M, Liu, Y, Yuen, P, Zheng, X, Dragovich, S.P, Wang, W.
登録日2013-06-08
公開日2014-06-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.445 Å)
主引用文献Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase.
Chembiochem, 15, 2014
4L4L
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Structural Analysis of a Phosphoribosylated Inhibitor in Complex with Human Nicotinamide Phosphoribosyltransferase
分子名称: 1,2-ETHANEDIOL, 6-({4-[(3,5-difluorophenyl)sulfonyl]benzyl}carbamoyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)imidazo[1,2-a]pyridin-1-ium, Nicotinamide phosphoribosyltransferase, ...
著者Oh, A, Ho, Y, Zak, M, Liu, Y, Yuen, P, Zheng, X, Dragovich, S.P, Wang, W.
登録日2013-06-08
公開日2014-06-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.122 Å)
主引用文献Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase.
Chembiochem, 15, 2014
8GQR
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Crystal structure of VioD with FAD
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, SULFATE ION, ...
著者Ran, T, Wang, W, Xu, M.
登録日2022-08-30
公開日2023-03-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for substrate binding and catalytic mechanism of the key enzyme VioD in the violacein synthesis pathway.
Proteins, 91, 2023
8GOY
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BU of 8goy by Molmil
SulE P44R
分子名称: 5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methyl-pyrazole-4-carboxylic acid, Alpha/beta fold hydrolase, GLYCEROL
著者Liu, B, He, J, Ran, T, Wang, W.
登録日2022-08-25
公開日2023-08-02
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.784 Å)
主引用文献Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity.
Nat Commun, 14, 2023
8GOL
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BU of 8gol by Molmil
crystal structure of SulE
分子名称: 2-[(4-chloranyl-6-methoxy-pyrimidin-2-yl)carbamoylsulfamoyl]benzoic acid, Alpha/beta fold hydrolase, GLYCEROL
著者Liu, B, Ran, T, Wang, W, He, J.
登録日2022-08-25
公開日2023-08-02
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity.
Nat Commun, 14, 2023
8GP0
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crystal structure of SulE
分子名称: Alpha/beta fold hydrolase, CITRIC ACID, GLYCEROL
著者Liu, B, Ran, T, wang, W, He, J.
登録日2022-08-25
公開日2023-08-02
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity.
Nat Commun, 14, 2023

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