7KED
RNA polymerase II elongation complex with unnatural base dTPT3
Summary for 7KED
Entry DOI | 10.2210/pdb7ked/pdb |
Descriptor | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC4, RNA, ... (15 entities in total) |
Functional Keywords | rna polymerase ii, elongation complex, unnatural base, tpt3, nam, transcription, transcription-dna-rna complex, transcription/dna/rna |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Total number of polymer chains | 13 |
Total formula weight | 487253.63 |
Authors | |
Primary citation | Oh, J.,Shin, J.,Unarta, I.C.,Wang, W.,Feldman, A.W.,Karadeema, R.J.,Xu, L.,Xu, J.,Chong, J.,Krishnamurthy, R.,Huang, X.,Romesberg, F.E.,Wang, D. Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II. Nat.Chem.Biol., 17:906-914, 2021 Cited by PubMed: 34140682DOI: 10.1038/s41589-021-00817-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
Download full validation report