7ET0
| Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CinA and CinB from wPip | 分子名称: | Bacteria factor A, Bacteria factor B | 著者 | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | 登録日 | 2021-05-12 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors. Proc.Natl.Acad.Sci.USA, 118, 2021
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1T6X
| Crystal structure of ADP bound TM379 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, riboflavin kinase/FMN adenylyltransferase | 著者 | Shin, D.H, Wang, W, Kim, R, Yokota, H, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2004-05-07 | 公開日 | 2004-08-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Crystal structure of ADP bound FAD synthetase To be Published
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2VG1
| Rv1086 E,E-farnesyl diphosphate complex | 分子名称: | FARNESYL DIPHOSPHATE, GLYCEROL, PHOSPHATE ION, ... | 著者 | Naismith, J.H, Wang, W, Dong, C. | 登録日 | 2007-11-07 | 公開日 | 2007-11-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The structural basis of chain length control in Rv1086. J. Mol. Biol., 381, 2008
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2VFW
| Rv1086 native | 分子名称: | SHORT-CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHETASE, SULFATE ION | 著者 | Naismith, J.H, Wang, W, Dong, C. | 登録日 | 2007-11-05 | 公開日 | 2007-11-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The structural basis of chain length control in Rv1086. J. Mol. Biol., 381, 2008
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1T6Z
| Crystal structure of riboflavin bound TM379 | 分子名称: | RIBOFLAVIN, riboflavin kinase/FMN adenylyltransferase | 著者 | Shin, D.H, Wang, W, Kim, R, Yokota, H, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2004-05-07 | 公開日 | 2004-08-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of ADP bound FAD synthetase To be Published
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1R54
| Crystal structure of the catalytic domain of human ADAM33 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADAM 33, CALCIUM ION, ... | 著者 | Orth, P, Reicher, P, Wang, W, Prosise, W.W, Yarosh-Tomaine, T, Hammond, G, Xiao, L, Mirza, U.A, Zou, J, Strickland, C, Taremi, S.S. | 登録日 | 2003-10-09 | 公開日 | 2004-10-12 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structre of the catalytic domain of human ADAM33 J.Mol.Biol., 335, 2004
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1T6Y
| Crystal structure of ADP, AMP, and FMN bound TM379 | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, ... | 著者 | Shin, D.H, Wang, W, Kim, R, Yokota, H, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2004-05-07 | 公開日 | 2004-08-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of ADP bound FAD synthetase To be Published
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5YIM
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5GXT
| Crystal structure of PigG | 分子名称: | MAGNESIUM ION, Maltose-binding periplasmic protein,PigG | 著者 | Zhang, F, Ran, T, Xu, D, Wang, W. | 登録日 | 2016-09-20 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | 主引用文献 | Crystal structure of MBP-PigG fusion protein and the essential function of PigG in the prodigiosin biosynthetic pathway in Serratia marcescens FS14. Int. J. Biol. Macromol., 99, 2017
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3LF5
| Structure of Human NADH cytochrome b5 oxidoreductase (Ncb5or) b5 Domain to 1.25A Resolution | 分子名称: | Cytochrome b5 reductase 4, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Deng, B, Parthasarathy, S, Wang, W, Gibney, B.R, Battaile, K.P, Lovell, S, Benson, D.R, Zhu, H. | 登録日 | 2010-01-15 | 公開日 | 2010-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Study of the individual cytochrome b5 and cytochrome b5 reductase domains of Ncb5or reveals a unique heme pocket and a possible role of the CS domain. J.Biol.Chem., 285, 2010
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5GWD
| Structure of Myroilysin | 分子名称: | Myroilysin, ZINC ION | 著者 | Xu, D, Ran, T, Wang, W. | 登録日 | 2016-09-10 | 公開日 | 2017-02-15 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Myroilysin Is a New Bacterial Member of the M12A Family of Metzincin Metallopeptidases and Is Activated by a Cysteine Switch Mechanism. J. Biol. Chem., 292, 2017
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5GXV
| Crystal structure of PigG | 分子名称: | MAGNESIUM ION, Maltose-binding periplasmic protein,PigG | 著者 | Zhang, F, Ran, T, Xu, D, Wang, W. | 登録日 | 2016-09-20 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of MBP-PigG fusion protein and the essential function of PigG in the prodigiosin biosynthetic pathway in Serratia marcescens FS14. Int. J. Biol. Macromol., 99, 2017
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4JR5
| Structure-based Identification of Ureas as Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors | 分子名称: | 1,2-ETHANEDIOL, 1-[4-(piperidin-1-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)thiourea, Nicotinamide phosphoribosyltransferase, ... | 著者 | Zheng, X, Bauer, P, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Han, B, Ho, Y, Kley, N, Lin, J, Reynolds, D.J, Sharma, G, Smith, C.C, Wang, Z, Dragovich, P.S, Oh, A, Wang, W, Zak, M, Gunzner-Toste, J, Zhao, G, Yuen, P, Bair, K.W. | 登録日 | 2013-03-21 | 公開日 | 2013-05-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.906 Å) | 主引用文献 | Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (nampt) inhibitors. J.Med.Chem., 56, 2013
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3L82
| X-ray Crystal structure of TRF1 and Fbx4 complex | 分子名称: | F-box only protein 4, Telomeric repeat-binding factor 1 | 著者 | Zeng, Z.X, Wang, W, Yang, Y.T, Chen, Y, Yang, X.M, Diehl, J.A, Liu, X.D, Lei, M. | 登録日 | 2009-12-29 | 公開日 | 2010-03-09 | 最終更新日 | 2013-09-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Basis of Selective Ubiquitination of TRF1 by SCF(Fbx4) Dev.Cell, 18, 2010
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4JNM
| Discovery of Potent and Efficacious Urea-containing Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors with Reduced CYP2C9 Inhibition Properties | 分子名称: | 1,2-ETHANEDIOL, 1-[(6-aminopyridin-3-yl)methyl]-3-[4-(phenylsulfonyl)phenyl]urea, Nicotinamide phosphoribosyltransferase, ... | 著者 | Gunzner-Toste, J, Zhao, G, Bauer, P, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Fu, B, Han, B, Ho, Y, Kley, N, Liederer, B, Lin, J, Mukadam, S, O'Brien, T, Reynolds, D.J, Sharma, G, Skelton, N, Smith, C.C, Oh, A, Wang, W, Wang, Z, Xiao, Y, Yuen, P, Zak, M, Zhang, L, Zheng, X, Bair, K.W, Dragovich, P.S. | 登録日 | 2013-03-15 | 公開日 | 2013-05-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties. Bioorg.Med.Chem.Lett., 23, 2013
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3VPI
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3VPJ
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3MWP
| Nucleoprotein structure of lassa fever virus | 分子名称: | Nucleoprotein, ZINC ION | 著者 | Qi, X, Lan, S, Wang, W, Schelde, L.M, Dong, H, Wallat, G, Liang, Y, Ly, H, Dong, C, Scottish Structural Proteomics Facility (SSPF) | 登録日 | 2010-05-06 | 公開日 | 2010-12-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.795 Å) | 主引用文献 | Cap binding and immune evasion revealed by Lassa nucleoprotein structure. Nature, 468, 2010
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3MX5
| Lassa fever virus nucleoprotein complexed with UTP | 分子名称: | Nucleoprotein, URIDINE 5'-TRIPHOSPHATE, ZINC ION | 著者 | Qi, X, Lan, S, Wang, W, Schelde, L.M, Dong, H, Wallat, G, Liang, Y, Ly, H, Dong, C, Scottish Structural Proteomics Facility (SSPF) | 登録日 | 2010-05-06 | 公開日 | 2010-12-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.903 Å) | 主引用文献 | Cap binding and immune evasion revealed by Lassa nucleoprotein structure. Nature, 468, 2010
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5H9U
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3MXN
| Crystal structure of the RMI core complex | 分子名称: | BENZAMIDINE, RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 | 著者 | Hoadley, K.A, Xu, D, Xue, Y, Satyshur, K.A, Wang, W, Keck, J.L. | 登録日 | 2010-05-07 | 公開日 | 2010-09-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure and cellular roles of the RMI core complex from the bloom syndrome dissolvasome. Structure, 18, 2010
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3MWT
| Crystal structure of Lassa fever virus nucleoprotein in complex with Mn2+ | 分子名称: | MANGANESE (II) ION, Nucleoprotein, ZINC ION | 著者 | Qi, X, Lan, S, Wang, W, Schelde, L.M, Dong, H, Wallat, G, Liang, Y, Ly, H, Dong, C, Scottish Structural Proteomics Facility (SSPF) | 登録日 | 2010-05-06 | 公開日 | 2010-12-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.982 Å) | 主引用文献 | Cap binding and immune evasion revealed by Lassa nucleoprotein structure. Nature, 468, 2010
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4KFP
| Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived Ureas as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | 分子名称: | 1,2-ETHANEDIOL, N-(4-{[1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl]sulfonyl}benzyl)-2H-pyrrolo[3,4-c]pyridine-2-carboxamide, Nicotinamide phosphoribosyltransferase, ... | 著者 | Dragovich, P.S, Bair, K.W, Baumeister, T, Ho, Y, Liederer, B.M, Liu, X, O'Brien, T, Oeh, J, Sampath, D, Skelton, N, Wang, L, Wang, W, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhang, L, Zheng, X. | 登録日 | 2013-04-27 | 公開日 | 2013-08-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorg.Med.Chem.Lett., 23, 2013
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3MX2
| Lassa fever virus Nucleoprotein complexed with dTTP | 分子名称: | Nucleoprotein, THYMIDINE-5'-TRIPHOSPHATE, ZINC ION | 著者 | Qi, X, Lan, S, Wang, W, Schelde, L.M, Dong, H, Wallat, G, Liang, Y, Ly, H, Dong, C, Scottish Structural Proteomics Facility (SSPF) | 登録日 | 2010-05-06 | 公開日 | 2010-12-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.983 Å) | 主引用文献 | Cap binding and immune evasion revealed by Lassa nucleoprotein structure. Nature, 468, 2010
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4LMQ
| Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12 | 分子名称: | Stromal cell-derived factor 1, hu30D8 Fab heavy chain, hu30D8 Fab light chain | 著者 | Zhong, Z, Wang, J, Li, B, Xiang, H, Ultsch, M, Coons, M, Wong, T, Chiang, N.Y, Clark, S, Clark, R, Quintana, L, Gribling, P, Suto, E, Barck, K, Corpuz, R, Yao, J, Takkar, R, Lee, W.P, Damico-Beyer, L.A, Carano, R.D, Adams, C, Kelley, R.F, Wang, W, Ferrara, N. | 登録日 | 2013-07-10 | 公開日 | 2013-08-14 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.773 Å) | 主引用文献 | Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12. Clin.Cancer Res., 19, 2013
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