4B5V

Crystal structures of divalent metal dependent pyruvate aldolase, HpaI, in complex with 4-hydroxyl-2-ketoheptane-1,7-dioate

Summary for 4B5V

Entry DOI	10.2210/pdb4b5v/pdb
Related	4B5S 4B5T 4B5U 4B5W 4B5X
Descriptor	4-HYDROXY-2-OXO-HEPTANE-1,7-DIOATE ALDOLASE, PYRUVIC ACID, (4R)-4-oxidanyl-2-oxidanylidene-heptanedioic acid, ... (6 entities in total)
Functional Keywords	lyase
Biological source	ESCHERICHIA COLI ATCC 8739
Total number of polymer chains	2
Total formula weight	54808.81
Authors	Coincon, M.,Wang, W.,Seah, S.Y.K.,Sygusch, J. (deposition date: 2012-08-07, release date: 2012-08-29, Last modification date: 2023-12-20)
Primary citation	Coincon, M.,Wang, W.,Sygusch, J.,Seah, S.Y.K. Crystal Structure of Reaction Intermediates in Pyruvate Class II Aldolase: Substrate Cleavage, Enolate Stabilization and Substrate Specificity J.Biol.Chem., 287:36208-, 2012 Cited by PubMed: 22908224 DOI: 10.1074/JBC.M112.400705 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.041 Å)

Structure validation