4B5U

Crystal structures of divalent metal dependent pyruvate aldolase, HpaI, in complex with pyruvate and succinic semialdehyde

Summary for 4B5U

Entry DOI	10.2210/pdb4b5u/pdb
Related	4B5S 4B5T 4B5V 4B5W 4B5X
Descriptor	4-HYDROXY-2-OXO-HEPTANE-1,7-DIOATE ALDOLASE, COBALT (II) ION, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	lyase, catalytic mechanism
Biological source	ESCHERICHIA COLI ATCC 8739
Total number of polymer chains	2
Total formula weight	54750.55
Authors	Coincon, M.,Wang, W.,Seah, S.Y.K.,Sygusch, J. (deposition date: 2012-08-07, release date: 2012-08-29, Last modification date: 2023-12-20)
Primary citation	Coincon, M.,Wang, W.,Sygusch, J.,Seah, S.Y.K. Crystal Structure of Reaction Intermediates in Pyruvate Class II Aldolase: Substrate Cleavage, Enolate Stabilization and Substrate Specificity J.Biol.Chem., 287:36208-, 2012 Cited by PubMed: 22908224 DOI: 10.1074/JBC.M112.400705 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.913 Å)

Structure validation