2OUS
 
 | | crystal structure of PDE10A2 mutant D674A | | Descriptor: | MAGNESIUM ION, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | | Authors: | Wang, H.C, Liu, Y.D, Hou, J, Zheng, M.Y, Robinson, H. | | Deposit date: | 2007-02-12 | | Release date: | 2007-03-20 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | From the Cover: Structural insight into substrate specificity of phosphodiesterase 10.
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
6LHE
 | | Crystal Structure of Gold-bound NDM-1 | | Descriptor: | GOLD ION, Metallo-beta-lactamase type 2, SULFATE ION | | Authors: | Wang, H, Sun, H, Wang, M. | | Deposit date: | 2019-12-07 | | Release date: | 2020-09-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.206 Å) | | Cite: | Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin.
Nat Commun, 11, 2020
|
|
3LFV
 | | crystal structure of unliganded PDE5A GAF domain | | Descriptor: | cGMP-specific 3',5'-cyclic phosphodiesterase | | Authors: | Wang, H, Robinson, H, Ke, H. | | Deposit date: | 2010-01-18 | | Release date: | 2010-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Conformation changes, N-terminal involvement, and cGMP signal relay in the phosphodiesterase-5 GAF domain.
J.Biol.Chem., 285, 2010
|
|
1WWI
 | | Crystal structure of ttk003001566 from Thermus Thermophilus HB8 | | Descriptor: | hypothetical protein TTHA1479 | | Authors: | Wang, H, Murayama, K, Terada, T, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-01-05 | | Release date: | 2005-07-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Crystal structure of ttk003001566 from Thermus Thermophilus HB8
TO BE PUBLISHED
|
|
2OUR
 | | crystal structure of PDE10A2 mutant D674A in complex with cAMP | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MAGNESIUM ION, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | | Authors: | Wang, H.C, Liu, Y.D, Hou, J, Zheng, M.Y, Robinson, H. | | Deposit date: | 2007-02-12 | | Release date: | 2007-03-20 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | From the Cover: Structural insight into substrate specificity of phosphodiesterase 10.
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
7MOJ
 | |
7MOF
 | | Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 6-diphosphoinositol 1,2,3,4,5-pentakisphosphate 6-InsP7 | | Descriptor: | (1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, INOSITOL HEXAKISPHOSPHATE, Tyrosine-protein phosphatase DSP1 | | Authors: | Wang, H, Shears, S.B. | | Deposit date: | 2021-05-01 | | Release date: | 2022-03-02 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
Nat Commun, 13, 2022
|
|
7MOE
 | | Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1)Cys150Ser in complex with 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate (5-InsP7) | | Descriptor: | (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, Tyrosine-protein phosphatase DSP1 | | Authors: | Wang, H, Shears, S.B. | | Deposit date: | 2021-05-01 | | Release date: | 2022-03-02 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
Nat Commun, 13, 2022
|
|
7MOG
 | | Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 5-PCF2 Am-InsP5, an analogue of 5-InsP7 | | Descriptor: | (1,1-difluoro-2-oxo-2-{[(1s,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]amino}ethyl)phosphonic acid, Tyrosine-protein phosphatase DSP1 | | Authors: | Wang, H, Shears, S.B. | | Deposit date: | 2021-05-01 | | Release date: | 2022-03-02 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
Nat Commun, 13, 2022
|
|
7MOH
 | | Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 5-diphosphoinositol 1,3,4,6-tetrakisphosphate (5PP-InsP4) and phosphate in conformation B (Pi(B)) | | Descriptor: | (1r,2R,3S,4r,5R,6S)-4-hydroxy-2,3,5,6-tetrakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, PHOSPHATE ION, Tyrosine-protein phosphatase DSP1 | | Authors: | Wang, H, Shears, S.B. | | Deposit date: | 2021-05-01 | | Release date: | 2022-03-02 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
Nat Commun, 13, 2022
|
|
7MOI
 | |
7MOD
 | |
7OHB
 | | TBP-nucleosome complex | | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Wang, H, Cramer, P. | | Deposit date: | 2021-05-10 | | Release date: | 2021-07-28 | | Last modified: | 2021-08-04 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7OHA
 | | nucleosome with TBP and TFIIA bound at SHL +2 | | Descriptor: | DNA (122-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Wang, H, Cramer, P. | | Deposit date: | 2021-05-09 | | Release date: | 2021-07-28 | | Last modified: | 2021-08-04 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7OH9
 | | Nucleosome with TBP and TFIIA bound at SHL -6 | | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Wang, H, Cramer, P. | | Deposit date: | 2021-05-09 | | Release date: | 2021-07-28 | | Last modified: | 2021-08-04 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7OHC
 | |
2CSL
 | | Crystal structure of TTHA0137 from Thermus Thermophilus HB8 | | Descriptor: | protein translation initiation inhibitor | | Authors: | Wang, H, Murayama, K, Terada, T, Chen, L, Jin, Z, Chrzas, J, Liu, Z.J, Wang, B.C, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-22 | | Release date: | 2005-11-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of TTHA0137 from Thermus Thermophilus HB8
To be Published
|
|
3MF0
 | | Crystal structure of PDE5A GAF domain (89-518) | | Descriptor: | cGMP-specific 3',5'-cyclic phosphodiesterase | | Authors: | Wang, H, Robinson, H, Ke, H. | | Deposit date: | 2010-04-01 | | Release date: | 2010-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Conformation changes, N-terminal involvement, and cGMP signal relay in the phosphodiesterase-5 GAF domain.
J.Biol.Chem., 285, 2010
|
|
5YS5
 | | Crystal structure of Multicopper Oxidase CueO G304K mutant with seven copper ions | | Descriptor: | Blue copper oxidase CueO, COPPER (II) ION | | Authors: | Wang, H.Q, Liu, X.Q, Zhao, J.T, Yue, Q.X, Yan, Y.H, Dong, Y.H, Fan, Y.L, Tian, J, Wu, N.F, Gong, Y. | | Deposit date: | 2017-11-13 | | Release date: | 2018-10-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of multicopper oxidase CueO G304K mutant: structural basis of the increased laccase activity
Sci Rep, 8, 2018
|
|
1YNS
 | | Crystal Structure Of Human Enolase-phosphatase E1 and its complex with a substrate analog | | Descriptor: | 2-OXOHEPTYLPHOSPHONIC ACID, E-1 enzyme, MAGNESIUM ION | | Authors: | Wang, H, Pang, H, Bartlam, M, Rao, Z. | | Deposit date: | 2005-01-25 | | Release date: | 2005-05-17 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of human e1 enzyme and its complex with a substrate analog reveals the mechanism of its phosphatase/enolase
J.Mol.Biol., 348, 2005
|
|
4MM4
 | |
4MMF
 | | Crystal structure of LeuBAT (delta5 mutant) in complex with mazindol | | Descriptor: | (5R)-5-(4-chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol, SODIUM ION, Transporter, ... | | Authors: | Wang, H, Gouaux, E. | | Deposit date: | 2013-09-08 | | Release date: | 2013-10-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
|
|
3O47
 | | Crystal structure of ARFGAP1-ARF1 fusion protein | | Descriptor: | ADP-ribosylation factor GTPase-activating protein 1, ADP-ribosylation factor 1, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Wang, H, Tong, Y, Nedyalkova, L, Tempel, W, Guan, X, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2010-07-26 | | Release date: | 2010-08-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of ARFGAP1-ARF1 fusion protein
to be published
|
|
6A9S
 | | The crystal structure of vaccinia virus A26 (residues 1-397) | | Descriptor: | 1,2-ETHANEDIOL, Protein A26 | | Authors: | Wang, H.C, Ko, T.Z, Luo, Y.C, Liao, Y.T, Chang, W. | | Deposit date: | 2018-07-16 | | Release date: | 2019-06-12 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (1.18 Å) | | Cite: | Vaccinia viral A26 protein is a fusion suppressor of mature virus and triggers membrane fusion through conformational change at low pH.
Plos Pathog., 15, 2019
|
|
1ZS9
 | | Crystal structure of human enolase-phosphatase E1 | | Descriptor: | E-1 ENZYME, MAGNESIUM ION | | Authors: | Wang, H, Pang, H, Bartlam, M, Rao, Z. | | Deposit date: | 2005-05-23 | | Release date: | 2005-06-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structure of Human E1 Enzyme and its Complex with a Substrate Analog Reveals the Mechanism of its Phosphatase/Enolase
J.Mol.Biol., 348, 2005
|
|
