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2OUQ

crystal structure of PDE10A2 in complex with GMP

Summary for 2OUQ
Entry DOI10.2210/pdb2ouq/pdb
Related2OUN 2OUP 2OUR 2OUS 2OUU 2OUV 2OUY
DescriptorcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywordspde, gmp complex, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: Q9Y233
Total number of polymer chains2
Total formula weight77154.81
Authors
Wang, H.C.,Liu, Y.D.,Hou, J.,Zheng, M.Y.,Robinson, H. (deposition date: 2007-02-12, release date: 2007-03-20, Last modification date: 2024-02-21)
Primary citationWang, H.,Liu, Y.,Hou, J.,Zheng, M.,Robinson, H.,Ke, H.
From the Cover: Structural insight into substrate specificity of phosphodiesterase 10.
Proc.Natl.Acad.Sci.Usa, 104:5782-5787, 2007
Cited by
PubMed: 17389385
DOI: 10.1073/pnas.0700279104
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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