1CGM

STRUCTURE DETERMINATION OF CUCUMBER GREEN MOTTLE MOSAIC VIRUS BY X-RAY FIBER DIFFRACTION. SIGNIFICANCE FOR THE EVOLUTION OF TOBAMOVIRUSES

Summary for 1CGM

• Entry DOI: 10.2210/pdb1cgm/pdb
• Descriptor: RNA (5'-R(P*GP*AP*A)-3'), CUCUMBER GREEN MOTTLE MOSAIC VIRUS (3 entities in total)
• Functional Keywords: virus, helical virus
• Biological source: Cucumber green mottle mosaic virus
• Total number of polymer chains: 2
• Total formula weight: 18261.88

Authors

Wang, H.,Stubbs, G. (deposition date: 1993-11-17, release date: 1994-04-30, Last modification date: 2024-11-13)

Primary citation

Wang, H.,Stubbs, G.
Structure determination of cucumber green mottle mosaic virus by X-ray fiber diffraction. Significance for the evolution of tobamoviruses.
J.Mol.Biol., 239:371-384, 1994

PubMed Abstract: Cucumber green mottle mosaic virus (CGMMV) is a rod-shaped virus of the tobacco mosaic virus (TMV) group. The structure of cucumber green mottle mosaic virus has been determined by fiber diffraction methods at 3.4 A resolution, and refined by molecular dynamics methods to an R factor of 0.093. Disassembly of TMV is driven by the mutual repulsion of intersubunit carboxyl-carboxylate pairs, but one of these pairs is not conserved in CGMMV. An alternative pair, located about 5 A from the site of the TMV pair, has been found in CGMMV. Comparison of the two structures suggests that the carboxylate groups are free to migrate in the subunit interfaces during evolution.

PubMed: 8201619
DOI: 10.1006/jmbi.1994.1379

Experimental method

FIBER DIFFRACTION (3.4 Å)