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PDB: 9 results
1Z7C
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BU of 1z7c by Molmil
Crystal Structure of Human Placental Lactogen
Descriptor: Chorionic somatomammotropin hormone
Authors:Walsh, S.T.R, Kossiakoff, A.A.
Deposit date:2005-03-24
Release date:2006-03-07
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure and Site 1 Binding Energetics of Human Placental Lactogen.
J.Mol.Biol., 358, 2006
2A3D
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BU of 2a3d by Molmil
SOLUTION STRUCTURE OF A DE NOVO DESIGNED SINGLE CHAIN THREE-HELIX BUNDLE (A3D)
Descriptor: PROTEIN (DE NOVO THREE-HELIX BUNDLE)
Authors:Walsh, S.T.R, Cheng, H, Bryson, J.W, Roder, H, Degrado, W.F.
Deposit date:1999-04-01
Release date:1999-05-05
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure and dynamics of a de novo designed three-helix bundle protein.
Proc.Natl.Acad.Sci.USA, 96, 1999
7S5B
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BU of 7s5b by Molmil
Unbound State of a De novo designed Protein Binder to the Human Interleukin-7 Receptor
Descriptor: Miniprotein Binder
Authors:Walsh, S.T.R, Cao, L, Baker, D.
Deposit date:2021-09-10
Release date:2022-05-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
6P4Y
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BU of 6p4y by Molmil
Crystal Structure of anti-IL-7Ralpha 4A10 Fab
Descriptor: 4A10 Fab heavy chain, 4A10 Fab light chain
Authors:Walsh, S.T.R, Kashi, L, Kohnhorst, C.L.
Deposit date:2019-05-29
Release date:2019-09-04
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.
Leukemia, 34, 2020
6P67
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BU of 6p67 by Molmil
Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha 2B8 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-IL-7R 2B8 Fab heavy chain, ...
Authors:Walsh, S.T.R, Kashi, L, Kohnhorst, C.L.
Deposit date:2019-06-03
Release date:2019-09-04
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.
Leukemia, 34, 2020
6P50
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BU of 6p50 by Molmil
Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha Fab 4A10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-7 receptor subunit alpha, anti-IL-7R 4A10 Fab heavy chain, ...
Authors:Walsh, S.T.R, Kashi, L, Kohnhorst, C.L.
Deposit date:2019-05-29
Release date:2019-09-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.
Leukemia, 34, 2020
3UP1
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BU of 3up1 by Molmil
Crystal structure of the unliganded human interleukin-7 receptor extracellular domain
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:McElroy, C.A, Holland, P.J, Walsh, S.T.R.
Deposit date:2011-11-17
Release date:2012-02-08
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural reorganization of the interleukin-7 signaling complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
3DI2
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BU of 3di2 by Molmil
Crystal structure of the complex of human interleukin-7 with unglycosylated human interleukin-7 receptor alpha ectodomain
Descriptor: Interleukin-7, Interleukin-7 receptor subunit alpha, PENTAETHYLENE GLYCOL
Authors:McElroy, C.A, Dohm, J.A, Walsh, S.T.R.
Deposit date:2008-06-19
Release date:2009-01-27
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Biophysical Studies of the Human IL-7/IL-7Ralpha Complex.
Structure, 17, 2009
3DI3
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BU of 3di3 by Molmil
Crystal structure of the complex of human interleukin-7 with glycosylated human interleukin-7 receptor alpha ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-7, Interleukin-7 receptor subunit alpha
Authors:McElroy, C.A, Dohm, J.A, Walsh, S.T.R.
Deposit date:2008-06-19
Release date:2009-01-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and Biophysical Studies of the Human IL-7/IL-7Ralpha Complex.
Structure, 17, 2009

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