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PDB: 901 results

7RDL
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Crystal structure of PCDN-22A, an anti-HIV antibody from the PCDN bnAb lineage
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PCDN-22A Fab heavy chain, PCDN-22A Fab light chain
Authors:Omorodion, O, Wilson, I.A.
Deposit date:2021-07-09
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural and Biochemical Characterization of Cysteinylation in Broadly Neutralizing Antibodies to HIV-1.
J.Mol.Biol., 433, 2021
7RDM
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Crystal structure of PCDN-38B, a broadly neutralizing anti-HIV antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, GLYCEROL, ...
Authors:Omorodion, O, Wilson, I.A.
Deposit date:2021-07-09
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural and Biochemical Characterization of Cysteinylation in Broadly Neutralizing Antibodies to HIV-1.
J.Mol.Biol., 433, 2021
7RDK
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Crystal structure of PCDN-16B, an anti-HIV antibody from the PCDN bnAb lineage (cysteinylated state)
Descriptor: 1,2-ETHANEDIOL, CYSTEINE, GLYCEROL, ...
Authors:Omorodion, O, Wilson, I.A.
Deposit date:2021-07-09
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structural and Biochemical Characterization of Cysteinylation in Broadly Neutralizing Antibodies to HIV-1.
J.Mol.Biol., 433, 2021
7RTP
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BU of 7rtp by Molmil
Structure of full-length human lambda-6A light chain JTO in complex with urea stabilizer 20 [1-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-3-(pyridin-3-ylmethyl)urea]
Descriptor: JTO light chain, N-{2-[7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl]ethyl}-N'-[(pyridin-3-yl)methyl]urea, PHOSPHATE ION
Authors:Yan, N.L, Wilson, I.A, Kelly, J.W.
Deposit date:2021-08-13
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site.
Bioorg.Med.Chem.Lett., 60, 2022
7S5Q
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BU of 7s5q by Molmil
Crystal structure of SARS-CoV-2 B.1.351 variant receptor binding domain in complex with neutralizing antibodies CS44 and COVA1-16
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 Heavy chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2021-09-11
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Science, 375, 2022
7S5R
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BU of 7s5r by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibodies CV07-287 and COVA1-16
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 Heavy chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2021-09-11
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Science, 375, 2022
7S5P
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BU of 7s5p by Molmil
Crystal structure of SARS-CoV-2 B.1.351 variant receptor binding domain in complex with neutralizing antibody CS23
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CS23 Heavy chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2021-09-11
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Science, 375, 2022
7RXI
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BU of 7rxi by Molmil
Fab234 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab234 heavy chain, Fab234 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXP
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Fab1512 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab1512 heavy chain, Fab1512 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.761 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXL
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Fab1488 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab1488 heavy chain, Fab1488 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.823 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXJ
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Fab236 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab236 heavy chain, Fab236 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.345 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7S0X
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Fab352 in complex with the C-terminal alphaTSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab352 heavy chain, Fab352 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-31
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7S0I
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BU of 7s0i by Molmil
CRYSTAL STRUCTURE OF N1 NEURAMINIDASE FROM A/Michigan/45/2015(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2021-08-30
Release date:2021-12-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.892 Å)
Cite:A Novel Recombinant Influenza Virus Neuraminidase Vaccine Candidate Stabilized by a Measles Virus Phosphoprotein Tetramerization Domain Provides Robust Protection from Virus Challenge in the Mouse Model.
Mbio, 12, 2021
6O3K
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BU of 6o3k by Molmil
Crystal structure of the unbound Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3
Descriptor: GLYCEROL, PGZL1.H4K3 heavy chain, PGZL1.H4K3 light chain, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2019-02-26
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6O3U
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BU of 6o3u by Molmil
Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with 06:0 PA
Descriptor: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, GLYCEROL, PGZL1.H4K3 heavy chain, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2019-02-27
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.105 Å)
Cite:An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6O30
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BU of 6o30 by Molmil
Lipid A transporter MsbA from Salmonella typhimurium
Descriptor: Lipid A export ATP-binding/permease protein MsbA
Authors:Padayatti, P.S, Zhang, Q, Wilson, I.A, Lee, S.C, Stanfield, R.L.
Deposit date:2019-02-25
Release date:2019-06-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.47 Å)
Cite:Structural Insights into the Lipid A Transport Pathway in MsbA.
Structure, 27, 2019
6O3D
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BU of 6o3d by Molmil
Crystal structure of the unbound Fab fragment of the human HIV-1 neutralizing antibody PGZL1.
Descriptor: GLYCEROL, PGZL1 FAB HEAVY CHAIN, PGZL1 FAB LIGHT CHAIN, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2019-02-26
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6O3J
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BU of 6o3j by Molmil
Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41) and phosphatidic acid (06:0 PA)
Descriptor: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, (4S)-2-METHYL-2,4-PENTANEDIOL, MPER peptide, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2019-02-26
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.416 Å)
Cite:An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6O3L
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BU of 6o3l by Molmil
Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41).
Descriptor: GLYCEROL, MPER peptide, region 671-683 of HIV-1 gp41, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2019-02-26
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6O41
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BU of 6o41 by Molmil
Crystal structure of the unbound PGZL1 germline Fab fragment (PGZL1_gVmDmJ)
Descriptor: GLYCEROL, Immunoglobulin G-binding protein G (DOMAIN III), germline PGZL1_gVmDmJ heavy chain, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2019-02-27
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.465 Å)
Cite:An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
4QDH
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BU of 4qdh by Molmil
Crystal Structure of the C-terminal Domain of Mouse TLR9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variable lymphocyte receptor B, ...
Authors:Collins, B.C, Wilson, I.A.
Deposit date:2014-05-13
Release date:2014-06-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Crystal structure of the C-terminal domain of mouse TLR9.
Proteins, 82, 2014
4XC1
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BU of 4xc1 by Molmil
Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 GP41: crystals cryoprotected with sn-Glycerol 3-phosphate
Descriptor: 4E10 FAB HEAVY CHAIN, 4E10 FAB LIGHT CHAIN, CYCLOHEXYLAMMONIUM ION, ...
Authors:Irimia, A, Stanfield, R.L, Wilson, I.A.
Deposit date:2014-12-17
Release date:2016-02-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XCE
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BU of 4xce by Molmil
Crystal structure of human 4E10 Fab crystalized in the presence of Phosphatidylcholine (06:0 PC); C2 space group
Descriptor: 4E10 Fab heavy chain, 4E10 Fab light chain
Authors:Irimia, A, Stanfield, R.L, Wilson, I.A.
Deposit date:2014-12-17
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4QGT
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BU of 4qgt by Molmil
The Crystal Structure of Human IgG Fc Domain with Enhanced Aromatic Sequon
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Kong, L, Connelly, S.C, Wilson, I.A.
Deposit date:2014-05-25
Release date:2015-04-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon.
Acs Chem.Biol., 11, 2016
3KU3
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BU of 3ku3 by Molmil
Crystal structure of a H2N2 influenza virus hemagglutinin, avian like
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2009-11-26
Release date:2010-01-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic.
J.Virol., 84, 2010

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數據於2024-09-11公開中

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