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PDB: 901 results

6O41
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BU of 6o41 by Molmil
Crystal structure of the unbound PGZL1 germline Fab fragment (PGZL1_gVmDmJ)
Descriptor: GLYCEROL, Immunoglobulin G-binding protein G (DOMAIN III), germline PGZL1_gVmDmJ heavy chain, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2019-02-27
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.465 Å)
Cite:An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
1GND
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BU of 1gnd by Molmil
GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM
Descriptor: GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR
Authors:Schalk, I, Zeng, K, Wu, S.-K, Stura, E.A, Metteson, J, Huang, M, Tandon, A, Wilson, I.A, Balch, W.E.
Deposit date:1996-07-10
Release date:1997-02-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structure and mutational analysis of Rab GDP-dissociation inhibitor.
Nature, 381, 1996
1GRC
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BU of 1grc by Molmil
CRYSTAL STRUCTURE OF GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE FROM ESCHERICHIA COLI AT 3.0 ANGSTROMS RESOLUTION: A TARGET ENZYME FOR CHEMOTHERAPY
Descriptor: GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, PHOSPHATE ION
Authors:Chen, P, Wilson, I.A.
Deposit date:1992-07-21
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of glycinamide ribonucleotide transformylase from Escherichia coli at 3.0 A resolution. A target enzyme for chemotherapy.
J.Mol.Biol., 227, 1992
1EBA
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BU of 1eba by Molmil
COMPLEX BETWEEN THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP] AND AN INACTIVE PEPTIDE [EMP33] CONTAINS 3,5-DIBROMOTYROSINE IN POSITION 4 (DENOTED DBY)
Descriptor: PROTEIN (EPO MIMETICS PEPTIDE 33), PROTEIN (ERYTHROPOIETIN RECEPTOR)
Authors:Livnah, O, Stura, E.A, Wilson, I.A.
Deposit date:1998-10-02
Release date:1998-11-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation.
Nat.Struct.Biol., 5, 1998
6UUL
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BU of 6uul by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody 438-D5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, D5 Fab Heavy Chain, ...
Authors:Kumar, S, Wilson, I.A.
Deposit date:2019-10-30
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:A V H 1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite.
Sci Adv, 6, 2020
6UYD
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BU of 6uyd by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2mc3-v1 redesigned core from genotype 1a bound to broadly neutralizing antibody AR3C
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Tzarum, N, Wilson, I.A, Zhu, J.
Deposit date:2019-11-13
Release date:2020-04-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
6UTK
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BU of 6utk by Molmil
Crystal structure of 438-B11 Fab in complex with an uncleaved prefusion optimized (UFO) soluble BG505 trimer and Fab 35O22 at 3.80 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kumar, S, Wilson, I.A.
Deposit date:2019-10-29
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite
Sci Adv, 6, 2020
6UUH
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BU of 6uuh by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody 438-B11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, B11 Fab Heavy Chain, B11 Fab Light Chain, ...
Authors:Kumar, S, Wilson, I.A.
Deposit date:2019-10-30
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A V H 1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite.
Sci Adv, 6, 2020
6UYM
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BU of 6uym by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2mc3-v6 redesigned core from genotype 1a bound to broadly neutralizing antibody AR3C
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Tzarum, N, Wilson, I.A, Zhu, J.
Deposit date:2019-11-13
Release date:2020-04-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.848 Å)
Cite:Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
6UYF
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BU of 6uyf by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2mc3-v1 redesigned core from genotype 6a bound to broadly neutralizing antibody AR3B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Tzarum, N, Wilson, I.A, Zhu, J.
Deposit date:2019-11-13
Release date:2020-04-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
6UYG
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BU of 6uyg by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2c3 core from genotype 6a bound to broadly neutralizing antibody AR3A and non neutralizing antibody E1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Tzarum, N, Wilson, I.A, Zhu, J.
Deposit date:2019-11-13
Release date:2020-04-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.375 Å)
Cite:Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines.
Sci Adv, 6, 2020
8E1P
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BU of 8e1p by Molmil
Crystal structure of BG505 SOSIP.v4.1-GT1.2 trimer in complex with gl-PGV20 and PGT124 Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIP.v4.1-GT1.2gp120, ...
Authors:Sarkar, A, Kumar, S, Wilson, I.A.
Deposit date:2022-08-11
Release date:2023-06-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.82 Å)
Cite:Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.
Cell Rep Med, 4, 2023
6V6W
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BU of 6v6w by Molmil
Crystal structure of antibody 438-B11 DSS mutant (Cys98A-100aA) in complex with an uncleaved prefusion optimized (UFO) soluble BG505 trimer and Fab 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab Heavy chain, ...
Authors:Kumar, S, Wilson, I.A.
Deposit date:2019-12-06
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (6.5 Å)
Cite:A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite
Sci Adv, 6, 2020
6VOS
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BU of 6vos by Molmil
Crystal structure of macaque anti-HIV-1 antibody RM20J
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, HEXAETHYLENE GLYCOL, NONAETHYLENE GLYCOL, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2020-01-31
Release date:2020-09-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
6VSR
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BU of 6vsr by Molmil
Crystal structure of macaque anti-HIV-1 antibody RM20F
Descriptor: RM20F Fab Heavy Chain, RM20F Fab Light Chain, SULFATE ION
Authors:Oyen, D, Yuan, M, Wilson, I.A.
Deposit date:2020-02-11
Release date:2020-09-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.176 Å)
Cite:Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
6VOR
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BU of 6vor by Molmil
Crystal structure of macaque anti-HIV-1 antibody RM20E1
Descriptor: GLYCINE, RM20E1 Fab heavy chain, RM20E1 Fab light chain
Authors:Yuan, M, Wilson, I.A.
Deposit date:2020-01-31
Release date:2020-09-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
6W41
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BU of 6w41 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody CR3022
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 Fab heavy chain, CR3022 Fab light chain, ...
Authors:Yuan, M, Wu, N.C, Zhu, X.Y, Wilson, I.A.
Deposit date:2020-03-09
Release date:2020-03-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.084 Å)
Cite:A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV.
Science, 368, 2020
6WJ0
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BU of 6wj0 by Molmil
Crystal structure of Fab 54-4H03
Descriptor: Fab 54-4H03 heavy chain, Fab 54-4H03 light chain, GLYCEROL
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2020-04-11
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
Cell Host Microbe, 28, 2020
6WO3
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BU of 6wo3 by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody U1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Tzarum, N, Wilson, I.A, Law, M.
Deposit date:2020-04-24
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.382 Å)
Cite:An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WJ1
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BU of 6wj1 by Molmil
Crystal structure of Fab 54-4H03 bound to H1 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 54-4H03 heavy chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2020-04-11
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
Cell Host Microbe, 28, 2020
6WO4
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BU of 6wo4 by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody HC11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Tzarum, N, Wilson, I.A, Law, M.
Deposit date:2020-04-24
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WO5
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BU of 6wo5 by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody 212.1.1 and non neutralizing antibody E1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Tzarum, N, Wilson, I.A, Law, M.
Deposit date:2020-04-24
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.619 Å)
Cite:An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WCR
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BU of 6wcr by Molmil
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule F0045(S)
Descriptor: (2,4-dichlorophenyl)[(2S)-2-phenylmorpholin-4-yl]methanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:kadam, R.U, Wilson, I.A.
Deposit date:2020-03-31
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.
Proc.Natl.Acad.Sci.USA, 117, 2020
6X1V
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BU of 6x1v by Molmil
Structure of pHis Fab (SC44-8) in complex with pHis mimetic peptide
Descriptor: 1,2-ETHANEDIOL, ACLYana-3-pTza peptide, SC44-8 Heavy chain, ...
Authors:Kalagiri, R, Stanfield, R, Wilson, I.A, Hunter, T.
Deposit date:2020-05-19
Release date:2021-02-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 118, 2021
6WOQ
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BU of 6woq by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody HC1AM and non neutralizing antibody E1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Tzarum, N, Wilson, I.A, Law, M.
Deposit date:2020-04-25
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.667 Å)
Cite:An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020

225946

數據於2024-10-09公開中

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