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PDB: 901 results

6BXE
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Crystal structure of Variable Lymphocyte Receptor 9 (VLR9)
Descriptor: Variable lymphocyte receptor diversity region
Authors:Gunn, R.J, Wilson, I.A, Cooper, M.D, Herrin, B.R.
Deposit date:2017-12-18
Release date:2018-05-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies.
J. Mol. Biol., 430, 2018
6BZU
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BU of 6bzu by Molmil
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 19B3
Descriptor: 19B3 Heavy Chain, 19B3 Light Chain, E2 AS412 peptide
Authors:Tzarum, N, Aleman, F, Kong, L, Wilson, I.A, Law, M.
Deposit date:2017-12-26
Release date:2018-06-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BZY
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Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the 22D11 broadly neutralizing antibody
Descriptor: 22D11 Heavy Chain, 22D11 Light Chain, E2 AS412 peptide
Authors:Tzarum, N, Aleman, F, Wilson, I.A, Law, M.
Deposit date:2017-12-26
Release date:2018-06-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BXC
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BU of 6bxc by Molmil
Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey Variable Lymphocyte Receptor 9 (VLR9) bound
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gunn, R.J, Wilson, I.A, Cooper, M.D, Herrin, B.R.
Deposit date:2017-12-18
Release date:2018-05-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies.
J. Mol. Biol., 430, 2018
6CFG
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Crystal structure of the A/Vietnam/1203/2004 (H5N1) influenza virus hemagglutinin in complex with small molecule JNJ4796
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Kadam, R.U, Wilson, I.A.
Deposit date:2018-02-14
Release date:2019-02-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:A small-molecule fusion inhibitor of influenza virus is orally active in mice.
Science, 363, 2019
6AOU
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Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin in complex with 3'-SLNLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-08-16
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
6AOV
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BU of 6aov by Molmil
Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin in complex with 6'-SLNLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-08-16
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
4L1T
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BU of 4l1t by Molmil
Transthyretin in complex with (E)-3-(dimethylamino)-5-(4-hydroxy-3,5-dimethylstyryl)benzoic acid
Descriptor: 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoic acid, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2013-06-03
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Fluorogenic small molecules requiring reaction with a specific protein to create a fluorescent conjugate for biological imaging-what we know and what we need to learn.
Biopolymers, 101, 2014
4JY5
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BU of 4jy5 by Molmil
Crystal structure of human Fab PGT122, a broadly reactive and potent HIV-1 neutralizing antibody
Descriptor: GLYCEROL, PGT122 heavy chain, PGT122 light chain
Authors:Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A.
Deposit date:2013-03-29
Release date:2013-05-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
Plos Pathog., 9, 2013
6B3D
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BU of 6b3d by Molmil
Crystal structure of anti-HIV antibody PGT128 in complex with a bacterially derived synthetic mimetic of Man9.
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
Authors:Murrell, S, Wilson, I.A.
Deposit date:2017-09-21
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.271 Å)
Cite:Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity.
Nat Commun, 8, 2017
1GND
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BU of 1gnd by Molmil
GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM
Descriptor: GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR
Authors:Schalk, I, Zeng, K, Wu, S.-K, Stura, E.A, Metteson, J, Huang, M, Tandon, A, Wilson, I.A, Balch, W.E.
Deposit date:1996-07-10
Release date:1997-02-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structure and mutational analysis of Rab GDP-dissociation inhibitor.
Nature, 381, 1996
6D0U
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BU of 6d0u by Molmil
Crystal structure of C05 V110P/A117E mutant bound to H3 influenza hemagglutinin, HA1 subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C05 V110P/A117E mutant, heavy chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2018-04-11
Release date:2019-01-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6CF7
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BU of 6cf7 by Molmil
Crystal structure of the A/Solomon Islands/3/2006(H1N1) influenza virus hemagglutinin in complex with small molecule JNJ4796
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Kadam, R.U, Wilson, I.A.
Deposit date:2018-02-13
Release date:2019-02-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.719 Å)
Cite:A small-molecule fusion inhibitor of influenza virus is orally active in mice.
Science, 363, 2019
4K3E
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BU of 4k3e by Molmil
Crystal structure of bovine antibody BLV5B8 with ultralong CDR H3
Descriptor: BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ...
Authors:Ekiert, D.C, Wang, F, Wilson, I.A.
Deposit date:2013-04-10
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Reshaping antibody diversity.
Cell(Cambridge,Mass.), 153, 2013
4K3X
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BU of 4k3x by Molmil
Crystal structure of a subtype H18 hemagglutinin homologue from A/flat-faced bat/Peru/033/2010 (H18N11)
Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-04-11
Release date:2013-10-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.149 Å)
Cite:New world bats harbor diverse influenza a viruses.
Plos Pathog., 9, 2013
4L1S
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BU of 4l1s by Molmil
Covalent modification of transthyretin K15 by yielding the fluorescent conjugate (E)-3-(dimethylamino)-5-(4-hydroxy-3,5-dimethylstyryl)benzamide
Descriptor: S-(4-fluorophenyl) 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzenecarbothioate, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2013-06-03
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Fluorogenic small molecules requiring reaction with a specific protein to create a fluorescent conjugate for biological imaging-what we know and what we need to learn.
Biopolymers, 101, 2014
2G2R
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BU of 2g2r by Molmil
Green-fluorescent antibody 11G10 in complex with its hapten (nitro-stilbene derivative)
Descriptor: Green-fluorescent antibody (11G10)-heavy chain, Green-fluorescent antibody (11G10)-light chain, N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID, ...
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2006-02-16
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The Effects of Antibodies on Stilbene Excited-State Energetics.
Angew.Chem.Int.Ed.Engl., 45, 2006
4LG2
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BU of 4lg2 by Molmil
Crystal structure of Reston Ebola virus VP35 RNA binding domain bound to 12-bp dsRNA
Descriptor: Polymerase cofactor, dsRNA
Authors:Bale, S, Julien, J.-P, Bornholdt, Z.A, Krois, A.S, Wilson, I.A, Saphire, E.O.
Deposit date:2013-06-27
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism.
J.Virol., 87, 2013
2I27
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BU of 2i27 by Molmil
Crystal Structure Analysis of the Nurse Shark New Antigen Receptor Ancestral variable domain
Descriptor: New Antigen Receptor Ancestral
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding.
J.Mol.Biol., 367, 2007
2I24
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BU of 2i24 by Molmil
Crystal structure analysis of the nurse shark New Antigen Receptor PBLA8 variable domain
Descriptor: CHLORIDE ION, New Antigen Receptor PBLA8
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding
J.Mol.Biol., 367, 2007
2I26
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BU of 2i26 by Molmil
Crystal structure analysis of the nurse shark new antigen receptor ancestral variable domain in complex with lysozyme
Descriptor: Lysozyme C, New Antigen Receptor Ancestral, SULFATE ION
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding.
J.Mol.Biol., 367, 2007
2I25
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BU of 2i25 by Molmil
Crystal structure analysis of the nurse shark New antigen Receptor PBLA8 variable domain in complex with lysozyme
Descriptor: Lysozyme C, New Antigen Receptor PBLA8
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding
J.Mol.Biol., 367, 2007
8SIR
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BU of 8sir by Molmil
Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with broadly neutralizing antibody CC25.54 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC25.54 Fab heavy chain, CC25.54 Fab light chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2023-04-16
Release date:2024-03-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift
Biorxiv, 2023
8SIS
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BU of 8sis by Molmil
Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with broadly neutralizing antibody CC84.2 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC84.2 Fab heavy chain, CC84.2 Fab light chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2023-04-16
Release date:2024-03-13
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift
Biorxiv, 2023
8SIT
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BU of 8sit by Molmil
Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with broadly neutralizing antibody CC84.24 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC84.24 fab heavy chain, CC84.24 fab light chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2023-04-16
Release date:2024-03-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift
Biorxiv, 2023

224931

数据于2024-09-11公开中

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