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PDB: 901 件

4NWT
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Crystal structure of the anti-human NGF Fab APE1531
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, APE1531 Ab Fab heavy chain, ...
著者Verdino, P, Stanfield, R.L, Wilson, I.A.
登録日2013-12-06
公開日2014-10-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies.
J.Biol.Chem., 289, 2014
4O5N
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BU of 4o5n by Molmil
Crystal structure of A/Victoria/361/2011 (H3N2) influenza virus hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
1HIM
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BU of 1him by Molmil
STRUCTURAL EVIDENCE FOR INDUCED FIT AS A MECHANISM FOR ANTIBODY-ANTIGEN RECOGNITION
分子名称: IGG2A-KAPPA 17/9 FAB (HEAVY CHAIN), IGG2A-KAPPA 17/9 FAB (LIGHT CHAIN), INFLUENZA HEMAGGLUTININ HA1 (STRAIN X47) (RESIDUES 100-108)
著者Schulze-Gahmen, U, Wilson, I.A.
登録日1992-07-08
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural evidence for induced fit as a mechanism for antibody-antigen recognition.
Science, 255, 1992
1HIN
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BU of 1hin by Molmil
STRUCTURAL EVIDENCE FOR INDUCED FIT AS A MECHANISM FOR ANTIBODY-ANTIGEN RECOGNITION
分子名称: IGG2A-KAPPA 17/9 FAB (HEAVY CHAIN), IGG2A-KAPPA 17/9 FAB (LIGHT CHAIN), INFLUENZA HEMAGGLUTININ HA1 (STRAIN X47) (RESIDUES 100-107)
著者Rini, J.M, Wilson, I.A.
登録日1992-07-08
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural evidence for induced fit as a mechanism for antibody-antigen recognition.
Science, 255, 1992
4MZA
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BU of 4mza by Molmil
Crystal structure of hPIV3 hemagglutinin-neuraminidase
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xu, R, Wilson, I.A.
登録日2013-09-29
公開日2013-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.653 Å)
主引用文献Interaction between the hemagglutinin-neuraminidase and fusion glycoproteins of human parainfluenza virus type III regulates viral growth in vivo.
MBio, 4, 2013
4N5Y
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BU of 4n5y by Molmil
Crystal structure of H5 hemagglutinin mutant (N158D, N224K and Q226L) from the influenza virus A/Viet Nam/1203/2004 (H5N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Zhu, X, Wilson, I.A.
登録日2013-10-10
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1615 Å)
主引用文献Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses.
J.Virol., 88, 2014
4N5Z
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BU of 4n5z by Molmil
Crystal structure of aerosol transmissible influenza H5 hemagglutinin mutant (N158D, N224K, Q226L and T318I) from the influenza virus A/Viet Nam/1203/2004 (H5N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Zhu, X, Wilson, I.A.
登録日2013-10-10
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9537 Å)
主引用文献Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses.
J.Virol., 88, 2014
1KJV
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BU of 1kjv by Molmil
TAP-B-associated rat MHC class I molecule
分子名称: Mature alpha chain of major histocompatibility complex class I antigen (HEAVY CHAIN), SULFATE ION, beta-2-microglobulin, ...
著者Rudolph, M.G, Stevens, J, Speir, J.A, Trowsdale, J, Butcher, G.W, Joly, E, Wilson, I.A.
登録日2001-12-05
公開日2002-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially with peptide transporter alleles TAP-A and TAP-B.
J.Mol.Biol., 324, 2002
4NGH
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BU of 4ngh by Molmil
Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41 and a tethered phosphate moiety.
分子名称: FAB HEAVY CHAIN, FAB LIGHT CHAIN, MODIFIED FRAGMENT OF HIV GLYCOPROTEIN (GP41)
著者Irimia, A, Wilson, I.A.
登録日2013-11-01
公開日2014-12-03
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.
Nat.Struct.Mol.Biol., 21, 2014
1KPV
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BU of 1kpv by Molmil
High resolution crystal structure of the MHC class I complex H-2Kb/SEV9
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class I histocompatibility antigen, ...
著者Rudolph, M.G, Wilson, I.A.
登録日2002-01-02
公開日2003-06-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献High Resolution Crystal Structure of H-2Kb/VSV8
To be Published
4NCO
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BU of 4nco by Molmil
Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP gp120, BG505 SOSIP gp41, ...
著者Julien, J.-P, Stanfield, R.L, Lyumkis, D, Ward, A.B, Wilson, I.A.
登録日2013-10-24
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.7 Å)
主引用文献Crystal structure of a soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
4NJ9
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BU of 4nj9 by Molmil
Crystal structure of Fab 8B10 in complex with MPTS
分子名称: 8-methoxypyrene-1,3,6-trisulfonic acid, 8B10 heavy chain, 8B10 light chain, ...
著者Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A.
登録日2013-11-08
公開日2014-11-12
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
8SIR
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BU of 8sir by Molmil
Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with broadly neutralizing antibody CC25.54 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC25.54 Fab heavy chain, CC25.54 Fab light chain, ...
著者Liu, H, Wilson, I.A.
登録日2023-04-16
公開日2024-03-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift
Biorxiv, 2023
8SIS
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BU of 8sis by Molmil
Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with broadly neutralizing antibody CC84.2 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC84.2 Fab heavy chain, CC84.2 Fab light chain, ...
著者Liu, H, Wilson, I.A.
登録日2023-04-16
公開日2024-03-13
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift
Biorxiv, 2023
8SIT
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BU of 8sit by Molmil
Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with broadly neutralizing antibody CC84.24 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC84.24 fab heavy chain, CC84.24 fab light chain, ...
著者Liu, H, Wilson, I.A.
登録日2023-04-16
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift
Biorxiv, 2023
8SIQ
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BU of 8siq by Molmil
Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with broadly neutralizing antibodies CC25.36 and CV38-142 Fab
分子名称: CC25.36 Fab heavy chain, CC25.36 Fab light chain, CV38-142 Fab heavy chain, ...
著者Liu, H, Wilson, I.A.
登録日2023-04-16
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift
Biorxiv, 2023
1KJM
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BU of 1kjm by Molmil
TAP-A-associated rat MHC class I molecule
分子名称: B6 Peptide, RT1 class I histocompatibility antigen, AA alpha chain, ...
著者Rudolph, M.G, Stevens, J, Speir, J.A, Trowsdale, J, Butcher, G.W, Joly, E, Wilson, I.A.
登録日2001-12-04
公開日2002-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially with peptide transporter alleles TAP-A and TAP-B.
J.Mol.Biol., 324, 2002
4O5L
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BU of 4o5l by Molmil
Crystal structure of broadly neutralizing antibody F045-092
分子名称: Fab F045-092 heavy chain, Fab F045-092 light chain, PHOSPHATE ION
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5045 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
4O5I
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BU of 4o5i by Molmil
Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/361/2011 (H3N2) influenza hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab F045-092 heavy chain, ...
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (6.501 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
4NPY
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BU of 4npy by Molmil
Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody
分子名称: GLYCEROL, germline PGT121 heavy chain, germline PGT121 light chain
著者Julien, J.-P, Diwanji, D.C, Wilson, I.A.
登録日2013-11-22
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.796 Å)
主引用文献The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies.
Plos Pathog., 9, 2013
4NHC
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BU of 4nhc by Molmil
Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41.
分子名称: FAB HEAVY CHAIN, FAB LIGHT CHAIN, MODIFIED FRAGMENT OF HIV GLYCOPROTEIN (GP41), ...
著者Irimia, A, Wilson, I.A.
登録日2013-11-04
公開日2014-12-03
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.912 Å)
主引用文献Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.
Nat.Struct.Mol.Biol., 21, 2014
4NJA
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BU of 4nja by Molmil
Crystal structure of Fab 6C8 in complex with MPTS
分子名称: 6C8 heavy chain, 6C8 light chain, 8-methoxypyrene-1,3,6-trisulfonic acid, ...
著者Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A.
登録日2013-11-08
公開日2014-11-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
1KPU
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BU of 1kpu by Molmil
High resolution crystal structure of the MHC class I complex H-2Kb/VSV8
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rudolph, M.G, Wilson, I.A.
登録日2002-01-02
公開日2003-06-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献High Resolution Crystal Structure of H-2Kb/VSV8
To be Published
4NUG
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BU of 4nug by Molmil
Crystal structure of HIV-1 broadly neutralizing antibody PGT151
分子名称: HEXAETHYLENE GLYCOL, PGT151 heavy chain, PGT151 light chain
著者Blattner, C, Wilson, I.A.
登録日2013-12-03
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8617 Å)
主引用文献Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers.
Immunity, 40, 2014
1LDP
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BU of 1ldp by Molmil
CRYSTAL STRUCTURE OF MURINE MHC CLASS I H-2LD WITH A MIXTURE OF BOUND PEPTIDES
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS I H-2LD, ...
著者Speir, J.A, Wilson, I.A.
登録日1998-03-15
公開日1998-06-17
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes.
Immunity, 8, 1998

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