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PDB: 887 件
8ED1
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Bovine Fab 5C1
分子名称: 5C1 Fab heavy chain, 5C1 Fab light chain, GLYCEROL, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2022-09-02
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EKF
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X-ray crystal structure of 311R Fab in complex with the PfCSP peptide NPNA-3
分子名称: 311R Heavy Chain, 311R Light Chain, PfCSP peptide NPNA-3
著者Moskovitz, R, Wilson, I.A.
登録日2022-09-20
公開日2022-10-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
6IEQ
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Crystal Structure of HIV-1 Env ConM SOSIP.v7 in Complex with bNAb PGT124 and 35O22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab Heavy Chain, ...
著者Han, B.W, Wilson, I.A.
登録日2018-09-16
公開日2019-05-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence.
Nat Commun, 10, 2019
35C8
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CATALYTIC ANTIBODY 5C8, FAB-INHIBITOR COMPLEX
分子名称: IGG 5C8, N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM-N-OXIDE
著者Gruber, K, Wilson, I.A.
登録日1998-03-18
公開日1999-03-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for antibody catalysis of a disfavored ring closure reaction.
Biochemistry, 38, 1999
5KUX
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BU of 5kux by Molmil
Designed influenza hemagglutinin binding protein HSB.2
分子名称: Designed influenza inhibitor protein HSB.2
著者Lee, P.S, Bernard, S.M, Wilson, I.A.
登録日2016-07-13
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.
Nat. Biotechnol., 35, 2017
5KUY
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Influenza hemagglutinin H3 A/Hong Kong/1/1968 in complex with designed inhibitor protein HSB.2A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Designed influenza inhibitor HSB.2A, ...
著者Bernard, S.M, Wilson, I.A.
登録日2016-07-13
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.598 Å)
主引用文献Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.
Nat. Biotechnol., 35, 2017
6E7G
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Crystal structure of H5 hemagglutinin mutant Y161A from A/Viet Nam/1203/2004 H5N1 influenza virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Tzarum, N, Wilson, I.A.
登録日2018-07-26
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.094 Å)
主引用文献N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses.
Cell Rep, 27, 2019
6E7H
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Crystal structure of H5 hemagglutinin mutant Y161A from A/Viet Nam/1203/2004 H5N1 influenza virus in complex with 3'-GcLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Tzarum, N, Wilson, I.A.
登録日2018-07-26
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses.
Cell Rep, 27, 2019
2R9U
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Crystal Structure of Lamprey Variable Lymphocyte Receptor 2913 Ectodomain
分子名称: Variable lymphocyte receptor
著者Han, B.W, Herrin, B.R, Choe, J, Cooper, M.D, Wilson, I.A.
登録日2007-09-13
公開日2009-03-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Lamprey Variable Lymphocyte Receptor 2913 Ectodomain.
To be Published
1ZHN
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BU of 1zhn by Molmil
Crystal Structure of mouse CD1d bound to the self ligand phosphatidylcholine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-[(DODECANOYLOXY)METHYL]-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-3,5,8-TRIOXA-4-PHOSPHADOTRIACONTAN-1-AMINIUM 4-OXIDE, CD1d1 antigen, ...
著者Giabbai, B, Sidobre, S, Crispin, M.M.D, Sanchez Ruiz, Y, Bachi, A, Kronenberg, M, Wilson, I.A, Degano, M.
登録日2005-04-26
公開日2005-07-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of mouse CD1d bound to the self ligand phosphatidylcholine: a molecular basis for NKT cell activation
J.Immunol., 175, 2005
6FYW
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Structure of B/Brisbane/60/2008 Influenza Hemagglutinin in complex with SD83
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Laursen, N.S, Wilson, I.A.
登録日2018-03-12
公開日2018-11-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6FYU
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BU of 6fyu by Molmil
Structure of H7(A/Shanghai/2/2013) Influenza Hemagglutinin in complex SD36
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Laursen, N.S, Wilson, I.A.
登録日2018-03-12
公開日2018-11-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.643 Å)
主引用文献Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6FYS
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BU of 6fys by Molmil
Structure of single domain antibody SD83
分子名称: 1,2-ETHANEDIOL, Single domain antibody SD83
著者Laursen, N.S, Wilson, I.A.
登録日2018-03-12
公開日2018-11-07
最終更新日2022-03-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6FYT
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BU of 6fyt by Molmil
Structure of H1 (A/solomon Islands/3/06) Influenza Hemagglutinin in complex with SD38
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Laursen, N.S, Wilson, I.A.
登録日2018-03-12
公開日2018-11-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
25C8
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BU of 25c8 by Molmil
CATALYTIC ANTIBODY 5C8, FAB-HAPTEN COMPLEX
分子名称: IGG 5C8, N-METHYL-N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM ION
著者Gruber, K, Wilson, I.A.
登録日1998-03-18
公開日1999-03-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for antibody catalysis of a disfavored ring closure reaction.
Biochemistry, 38, 1999
2R6Q
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BU of 2r6q by Molmil
Crystal Structure of BclA-island Construct
分子名称: BclA protein
著者Han, B.W, Herrin, B.R, Turnbough Jr, C.L, Cooper, M.D, Wilson, I.A.
登録日2007-09-06
公開日2009-03-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Crystal structure of BclA-island Construct
To be Published
5XRT
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BU of 5xrt by Molmil
Crystal structure of A/Minnesota/11/2010 (H3N2) influenza virus hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhang, H, Wilson, I.A.
登録日2017-06-09
公開日2018-07-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA.
Nat Commun, 9, 2018
5XRS
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Crystal structure of A/Minnesota/11/2010 (H3N2) influenza virus hemagglutinin in complex with LSTc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, ...
著者Zhang, H, Wilson, I.A.
登録日2017-06-09
公開日2018-07-25
最終更新日2022-10-12
実験手法X-RAY DIFFRACTION (2.907 Å)
主引用文献A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA.
Nat Commun, 9, 2018
5WDU
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BU of 5wdu by Molmil
HIV-1 Env BG505 SOSIP.664 H72C-H564C trimer in complex with bNAbs PGT122 Fab, 35O22 Fab and NIH45-46 scFv
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Julien, J.-P, Torrents de la Pena, A, Sanders, R.W, Wilson, I.A.
登録日2017-07-06
公開日2018-04-04
最終更新日2022-11-30
実験手法X-RAY DIFFRACTION (7 Å)
主引用文献Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.
Cell Rep, 20, 2017
5VTZ
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Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225Q/L226A mutant apo form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2017-05-18
公開日2017-06-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5W6D
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BU of 5w6d by Molmil
Crystal structure of BG505-SOSIP.v4.1-GT1-N137A in complex with Fabs 35022 and 9H/109L
分子名称: 109L FAB light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Garces, F, Stanfield, R.L, Wilson, I.A.
登録日2017-06-16
公開日2017-07-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.202 Å)
主引用文献Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.
J. Exp. Med., 214, 2017
5WK4
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Crystal structure of an anti-idiotype VLR
分子名称: MAGNESIUM ION, Variable lymphocyte receptor 39
著者Collins, B.C, Nakahara, H, Cooper, M.D, Herrin, B.R, Wilson, I.A.
登録日2017-07-24
公開日2017-12-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.498 Å)
主引用文献Crystal structure of an anti-idiotype variable lymphocyte receptor.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5YL9
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1.86 Angstrom crystal structure of human Coronavirus 229E fusion core
分子名称: Spike glycoprotein
著者Yang, B, Yan, L, Meng, B, WIlson, I.A.
登録日2017-10-17
公開日2018-09-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.861 Å)
主引用文献Crystal structure of the post-fusion core of the Human coronavirus 229E spike protein at 1.86 angstrom resolution
Acta Crystallogr D Struct Biol, 74, 2018
5VTV
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Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225M/L226T/S228A mutant in complex with 3'-SLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2017-05-18
公開日2017-06-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5VTQ
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Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225L/L226S mutant in complex with 3'-SLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2017-05-17
公開日2017-06-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017

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