5KUX

Designed influenza hemagglutinin binding protein HSB.2

Summary for 5KUX

Entry DOI	10.2210/pdb5kux/pdb
Related	5KUY
Descriptor	Designed influenza inhibitor protein HSB.2 (2 entities in total)
Functional Keywords	influenza, inhibitor, designed protein, cystatin, protein binding
Biological source	synthetic construct
Total number of polymer chains	1
Total formula weight	11017.27
Authors	Lee, P.S.,Bernard, S.M.,Wilson, I.A. (deposition date: 2016-07-13, release date: 2017-06-14, Last modification date: 2023-10-04)
Primary citation	Strauch, E.M.,Bernard, S.M.,La, D.,Bohn, A.J.,Lee, P.S.,Anderson, C.E.,Nieusma, T.,Holstein, C.A.,Garcia, N.K.,Hooper, K.A.,Ravichandran, R.,Nelson, J.W.,Sheffler, W.,Bloom, J.D.,Lee, K.K.,Ward, A.B.,Yager, P.,Fuller, D.H.,Wilson, I.A.,Baker, D. Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site. Nat. Biotechnol., 35:667-671, 2017 Cited by PubMed: 28604661 DOI: 10.1038/nbt.3907 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation