8EKF

X-ray crystal structure of 311R Fab in complex with the PfCSP peptide NPNA-3

This is a non-PDB format compatible entry.

Summary for 8EKF

• Entry DOI: 10.2210/pdb8ekf/pdb
• Related: 6AXK
• Descriptor: 311R Heavy Chain, 311R Light Chain, PfCSP peptide NPNA-3, ... (4 entities in total)
• Functional Keywords: antibody, antigen, malaria, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 47974.31

Authors

Moskovitz, R.,Wilson, I.A. (deposition date: 2022-09-20, release date: 2022-10-19, Last modification date: 2023-11-01)

• Primary citation: Martin, G.M.,Torres, J.L.,Pholcharee, T.,Oyen, D.,Flores-Garcia, Y.,Gibson, G.,Moskovitz, R.,Beutler, N.,Jung, D.D.,Copps, J.,Lee, W.H.,Gonzalez-Paez, G.,Emerling, D.,MacGill, R.S.,Locke, E.,King, C.R.,Zavala, F.,Wilson, I.A.,Ward, A.B.; Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.; Nat Commun, 14:4546-4546, 2023; PubMed: 37507365; DOI: 10.1038/s41467-023-40151-x

Experimental method

X-RAY DIFFRACTION (1.9 Å)