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PDB: 887 件

3QQI
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Crystal structure of the HA1 receptor binding domain of H2 hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hemagglutinin
著者Xu, R, Wilson, I.A.
登録日2011-02-15
公開日2011-03-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Characterization of an Early Fusion Intermediate of Influenza Virus Hemagglutinin.
J.Virol., 85, 2011
3R06
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Crystal structure of anti-mouse CD3epsilon antibody 2C11 Fab fragment
分子名称: anti-mouse CD3epsilon antibody 2C11 Fab heavy chain, anti-mouse CD3epsilon antibody 2C11 Fab light chain
著者Shore, D.A, Zhu, X, Wilson, I.A.
登録日2011-03-07
公開日2012-01-25
最終更新日2013-09-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements.
J.Biol.Chem., 287, 2012
3SDY
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Crystal Structure of Broadly Neutralizing Antibody CR8020 Bound to the Influenza A H3 Hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8020, Heavy Chain, ...
著者Ekiert, D.C, Wilson, I.A.
登録日2011-06-09
公開日2011-07-20
最終更新日2021-04-07
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A highly conserved neutralizing epitope on group 2 influenza A viruses.
Science, 333, 2011
3T0W
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Fluorogen activating protein M8VL in complex with dimethylindole red
分子名称: 1-(3-sulfopropyl)-4-[(1E,3E)-3-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)prop-1-en-1-yl]quinolinium, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ...
著者Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P.
登録日2011-07-20
公開日2012-03-21
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
3QHF
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Crystal Structure of Fab del2D1, a deletion variant of anti-influenza antibody 2D1
分子名称: Human monoclonal antibody del2D1, Fab Heavy Chain, Fab Light Chain
著者Ekiert, D.C, Wilson, I.A.
登録日2011-01-25
公開日2011-02-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.655 Å)
主引用文献An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
MBio, 2, 2011
3QHZ
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Crystal Structure of human anti-influenza Fab 2D1
分子名称: Human monoclonal antibody del2D1, Fab Heavy Chain, Fab Light Chain
著者Ekiert, D.C, Wilson, I.A.
登録日2011-01-26
公開日2011-02-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
MBio, 2, 2011
3T0X
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Fluorogen Activating Protein M8VLA4(S55P) in complex with dimethylindole red
分子名称: 1,2-ETHANEDIOL, 1-(3-sulfopropyl)-4-[(1E,3E)-3-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)prop-1-en-1-yl]quinolinium, Immunoglobulin variable lambda domain M8VLA4(S55P), ...
著者Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P.
登録日2011-07-20
公開日2012-03-21
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
3T0V
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Unliganded fluorogen activating protein M8VL
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ...
著者Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P.
登録日2011-07-20
公開日2012-03-21
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
3TCT
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Structure of wild-type TTR in complex with tafamidis
分子名称: 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin
著者Connelly, S, Kelly, J.W, Wilson, I.A.
登録日2011-08-09
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade.
Proc.Natl.Acad.Sci.USA, 109, 2012
3R08
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Crystal structure of mouse cd3epsilon in complex with antibody 2C11 Fab
分子名称: Mouse anti-mouse CD3epsilon antibody 2C11 heavy chain, Mouse anti-mouse CD3epsilon antibody 2C11 light chain, T-cell surface glycoprotein CD3 epsilon chain
著者Shore, D.A, Zhu, X, Wilson, I.A.
登録日2011-03-07
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements.
J.Biol.Chem., 287, 2012
3R2X
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Crystal structure of the de novo designed binding protein HB36.3 in complex the the 1918 influenza virus hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HB36.3, designed hemagglutinin binding protein, ...
著者Ekiert, D.C, Wilson, I.A.
登録日2011-03-14
公開日2011-05-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Computational design of proteins targeting the conserved stem region of influenza hemagglutinin.
Science, 332, 2011
3TV3
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Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with Man9
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMYLAMINE, GLYCEROL, ...
著者Pejchal, R, Wilson, I.A.
登録日2011-09-19
公開日2011-10-19
最終更新日2021-04-28
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Science, 334, 2011
3U1S
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Crystal structure of human Fab PGT145, a broadly reactive and potent HIV-1 neutralizing antibody
分子名称: Fab PGT145 Heavy chain, Fab PGT145 Light chain, GLYCEROL, ...
著者Julien, J.-P, Diwanji, D, Burton, D.R, Wilson, I.A.
登録日2011-09-30
公開日2011-12-07
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3UBQ
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Influenza hemagglutinin from the 2009 pandemic in complex with ligand 3SLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ...
著者Xu, R, Wilson, I.A.
登録日2011-10-24
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic.
J.Virol., 86, 2012
3Q1S
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HIV-1 neutralizing antibody Z13e1 in complex with epitope display protein
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Interleukin-22, ...
著者Stanfield, R.L, Julien, J.-P, Pejchal, R, Gach, J.S, Zwick, M.B, Wilson, I.A.
登録日2010-12-17
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure-Based Design of a Protein Immunogen that Displays an HIV-1 gp41 Neutralizing Epitope.
J.Mol.Biol., 414, 2011
3TWC
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BU of 3twc by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody PGT127 in complex with Man9
分子名称: AMYLAMINE, PGT127 heavy chain, Ig gamma-1 chain C region, ...
著者Pejchal, R, Wilson, I.A.
登録日2011-09-21
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Science, 334, 2011
3TYG
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BU of 3tyg by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with a glycosylated engineered gp120 outer domain with miniV3 (eODmV3)
分子名称: Envelope glycoprotein gp160, PGT128 heavy chain, Ig gamma-1 chain C region, ...
著者Pejchal, R, Huang, P.S, Schief, W.R, Stanfield, R.L, Wilson, I.A.
登録日2011-09-25
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Science, 334, 2011
3UBE
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BU of 3ube by Molmil
Influenza hemagglutinin from the 2009 pandemic in complex with ligand LSTc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者Xu, R, Wilson, I.A.
登録日2011-10-24
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic.
J.Virol., 86, 2012
3UBJ
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BU of 3ubj by Molmil
Influenza hemagglutinin from the 2009 pandemic in complex with ligand LSTa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者Xu, R, Wilson, I.A.
登録日2011-10-24
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic.
J.Virol., 86, 2012
3UBN
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Influenza hemagglutinin from the 2009 pandemic in complex with ligand 6SLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者Xu, R, Wilson, I.A.
登録日2011-10-24
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5079 Å)
主引用文献Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic.
J.Virol., 86, 2012
3TWI
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Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores
分子名称: BclA protein, GLYCEROL, Variable lymphocyte receptor B
著者Kirchdoerfer, R.N, Herrin, B.R, Han, B.W, Turnbough Jr, C.L, Cooper, M.D, Wilson, I.A.
登録日2011-09-21
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores.
Structure, 20, 2012
3TYJ
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Bacillus collagen-like protein of anthracis P159S mutant
分子名称: BclA protein
著者Kirchdoerfer, R.N, Herrin, B.R, Han, B.W, Turnbough Jr, C.L, Cooper, M.D, Wilson, I.A.
登録日2011-09-26
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores.
Structure, 20, 2012
1DBB
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THREE-DIMENSIONAL STRUCTURE OF AN ANTI-STEROID FAB' AND PROGESTERONE-FAB' COMPLEX
分子名称: IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN), PROGESTERONE
著者Arevalo, J.H, Wilson, I.A.
登録日1992-11-11
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Three-dimensional structure of an anti-steroid Fab' and progesterone-Fab' complex.
J.Mol.Biol., 231, 1993
1ERN
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BU of 1ern by Molmil
NATIVE STRUCTURE OF THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP]
分子名称: PROTEIN (ERYTHROPOIETIN RECEPTOR)
著者Livnah, O, Stura, E.A, Wilson, I.A.
登録日1999-01-11
公開日2000-01-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation.
Science, 283, 1999
7JN5
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Crystal structure of SARS-CoV receptor binding domain in complex with human antibody CR3022
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 heavy chain, ...
著者Wu, N.C, Yuan, M, Zhu, X, Wilson, I.A.
登録日2020-08-03
公開日2020-10-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.705 Å)
主引用文献A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody.
Plos Pathog., 16, 2020

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