6J75
 
 | | Structure of 3,6-anhydro-L-galactose Dehydrogenase | | 分子名称: | Aldehyde dehydrogenase A | | 著者 | Li, P.Y, Wang, Y, Chen, X.L, Zhang, Y.Z. | | 登録日 | 2019-01-17 | | 公開日 | 2020-01-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.695 Å) | | 主引用文献 | 3,6-Anhydro-L-Galactose Dehydrogenase VvAHGD is a Member of a New Aldehyde Dehydrogenase Family and Catalyzes by a Novel Mechanism with Conformational Switch of Two Catalytic Residues Cysteine 282 and Glutamate 248.
J.Mol.Biol., 432, 2020
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3GO6
 | | Crystal Structure of M. tuberculosis ribokinase (Rv2436) in complex with ribose and AMP-PNP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RIBOKINASE RBSK, ... | | 著者 | Masters, E.I, Sun, Y, Wang, Y, Parker, W.B, Li, R. | | 登録日 | 2009-03-18 | | 公開日 | 2010-03-31 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystal structure and biochemical characterization of M.tuberculosis ribokinase (Rv2436)
To be Published
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3OXC
 | | Wild Type HIV-1 Protease with Antiviral Drug Saquinavir | | 分子名称: | (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, FORMIC ACID, Protease, ... | | 著者 | Kovalevsky, A.Y, Wang, Y.-F, Tie, Y, Weber, I.T. | | 登録日 | 2010-09-21 | | 公開日 | 2010-11-10 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | | 主引用文献 | Atomic resolution crystal structures of HIV-1 protease and mutants V82A and I84V with saquinavir
Proteins, 67, 2007
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2AOC
 | | Crystal structure analysis of HIV-1 protease mutant I84V with a substrate analog P2-NC | | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | | 登録日 | 2005-08-12 | | 公開日 | 2006-01-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.
Febs J., 272, 2005
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2AOG
 | | Crystal structure analysis of HIV-1 protease mutant V82A with a substrate analog P2-NC | | 分子名称: | ACETIC ACID, GLYCEROL, HIV-1 PROTEASE (RETROPEPSIN), ... | | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | | 登録日 | 2005-08-12 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.
Febs J., 272, 2005
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2AOD
 | | Crystal structure analysis of HIV-1 protease with a substrate analog P2-NC | | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, HIV-1 PROTEASE, ... | | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | | 登録日 | 2005-08-12 | | 公開日 | 2006-01-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.
Febs J., 272, 2005
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1YT3
 | | Crystal Structure of Escherichia coli RNase D, an exoribonuclease involved in structured RNA processing | | 分子名称: | Ribonuclease D, SULFATE ION, ZINC ION | | 著者 | Zuo, Y, Wang, Y, Malhotra, A. | | 登録日 | 2005-02-09 | | 公開日 | 2005-08-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of Escherichia coli RNase D, an Exoribonuclease Involved in Structured RNA Processing
Structure, 13, 2005
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5EZK
 | | RNA polymerase model placed by Molecular replacement into X-ray diffraction map of DNA-bound RNA Polymerase-Sigma 54 holoenzyme complex. | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Darbari, V.C, Yang, Y, Lu, D, Zhang, N, Glyde, R, Wang, Y, Murakami, K.S, Buck, M, Zhang, X. | | 登録日 | 2015-11-26 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (8.5 Å) | | 主引用文献 | TRANSCRIPTION. Structures of the RNA polymerase- Sigma 54 reveal new and conserved regulatory strategies.
Science, 349, 2015
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6E6S
 | | 1.45 A resolution structure of the C-terminally truncated [2Fe-2S] ferredoxin (Bfd) R26E/K46Y mutant from Pseudomonas aeruginosa | | 分子名称: | Bacterioferritin-associated ferredoxin, FE2/S2 (INORGANIC) CLUSTER | | 著者 | Lovell, S, Wijerathne, H, Battaile, K.P, Yao, H, Wang, Y, Rivera, M. | | 登録日 | 2018-07-25 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Bfd, a New Class of [2Fe-2S] Protein That Functions in Bacterial Iron Homeostasis, Requires a Structural Anion Binding Site.
Biochemistry, 57, 2018
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6E6Q
 | | 1.20 A resolution structure of the C-terminally truncated [2Fe-2S] ferredoxin (Bfd) from Pseudomonas aeruginosa | | 分子名称: | Bacterioferritin-associated ferredoxin, FE2/S2 (INORGANIC) CLUSTER | | 著者 | Lovell, S, Wijerathne, H, Battaile, K.P, Yao, H, Wang, Y, Rivera, M. | | 登録日 | 2018-07-25 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Bfd, a New Class of [2Fe-2S] Protein That Functions in Bacterial Iron Homeostasis, Requires a Structural Anion Binding Site.
Biochemistry, 57, 2018
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8H0O
 | | Crystal structure of human serum albumin and ruthenium PZA complex adduct | | 分子名称: | Albumin, CHLORIDE ION, NITRIC OXIDE, ... | | 著者 | Gong, W.J, Wang, Y, Bai, H.H, Wang, W.M, Wang, H.F. | | 登録日 | 2022-09-30 | | 公開日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.479 Å) | | 主引用文献 | Crystal structure of human serum albumin and ruthenium PZA complex adduct
To Be Published
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6E6R
 | | 1.50 A resolution structure of the C-terminally truncated [2Fe-2S] ferredoxin (Bfd) R26E mutant from Pseudomonas aeruginosa | | 分子名称: | Bacterioferritin-associated ferredoxin, FE2/S2 (INORGANIC) CLUSTER | | 著者 | Lovell, S, Wijerathne, H, Battaile, K.P, Yao, H, Wang, Y, Rivera, M. | | 登録日 | 2018-07-25 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Bfd, a New Class of [2Fe-2S] Protein That Functions in Bacterial Iron Homeostasis, Requires a Structural Anion Binding Site.
Biochemistry, 57, 2018
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7VJL
 | | The crystal structure of FGFR4 kinase domain in complex with N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-(2,2,2-trifluoroacetyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide | | 分子名称: | Fibroblast growth factor receptor 4, N-[5-(aminomethyl)-4-(2-methoxyethylamino)pyridin-2-yl]-7-[2,2,2-tris(fluoranyl)ethanoyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide | | 著者 | Zhang, Z.M, Wang, Y.J. | | 登録日 | 2021-09-28 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.900173 Å) | | 主引用文献 | Characterization of an aromatic trifluoromethyl ketone as a new warhead for covalently reversible kinase inhibitor design.
Bioorg.Med.Chem., 50, 2021
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1A52
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7XZ4
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2AOJ
 | | Crystal structure analysis of HIV-1 protease with a substrate analog P6-PR | | 分子名称: | ACETIC ACID, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | | 登録日 | 2005-08-12 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.
Febs J., 272, 2005
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1A8E
 | | HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE | | 分子名称: | CARBONATE ION, FE (III) ION, SERUM TRANSFERRIN | | 著者 | Macgillivray, R.T.A, Moore, S.A, Chen, J, Anderson, B.F, Baker, H, Luo, Y, Bewley, M, Smith, C.A, Murphy, M.E.P, Wang, Y, Mason, A.B, Woodworth, R.C, Brayer, G.D, Baker, E.N. | | 登録日 | 1998-03-24 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release.
Biochemistry, 37, 1998
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2AOE
 | | crystal structure analysis of HIV-1 protease mutant V82A with a substrate analog CA-P2 | | 分子名称: | ACETIC ACID, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | | 登録日 | 2005-08-12 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.
Febs J., 272, 2005
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7YK6
 | | Cryo-EM structure of the compound 4-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex | | 分子名称: | 1-[2-(4-chlorophenyl)ethyl]-3-[(7-ethyl-5-oxidanyl-1H-indol-3-yl)methylideneamino]guanidine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Chen, Y, Zhou, Q.T, Wang, J, Xu, Y.W, Wang, Y, Yan, J.H, Wang, Y.B, Zhu, Q, Zhao, F.H, Li, C.H, Chen, C.W, Cai, X.Q, Bathgate, R.A.D, Shen, C, Liu, H, Xu, H.E, Yang, D.H, Wang, M.W. | | 登録日 | 2022-07-21 | | 公開日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4).
Nat Commun, 14, 2023
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7YJ4
 | | Cryo-EM structure of the INSL5-bound human relaxin family peptidereceptor 4 (RXFP4)-Gi complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-2, ... | | 著者 | Chen, Y, Zhou, Q.T, Wang, J, Xu, Y.W, Wang, Y, Yan, J.H, Wang, Y.B, Zhu, Q, Zhao, F.H, Li, C.H, Chen, C.W, Cai, X.Q, Bathgate, R.A.D, Shen, C, Liu, H, Xu, H.E, Yang, D.H, Wang, M.W. | | 登録日 | 2022-07-19 | | 公開日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4).
Nat Commun, 14, 2023
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7YK7
 | | Cryo-EM structure of the DC591053-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-2, ... | | 著者 | Chen, Y, Zhou, Q.T, Wang, J, Xu, Y.W, Wang, Y, Yan, J.H, Wang, Y.B, Zhu, Q, Zhao, F.H, Li, C.H, Chen, C.W, Cai, X.Q, Bathgate, R.A.D, Shen, C, Xu, H.E, Yang, D.H, Liu, H, Wang, M.W. | | 登録日 | 2022-07-21 | | 公開日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4).
Nat Commun, 14, 2023
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2AOF
 | | Crystal structure analysis of HIV-1 Protease mutant V82A with a substrate analog P1-P6 | | 分子名称: | ACETIC ACID, CHLORIDE ION, PEPTIDE INHIBITOR, ... | | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | | 登録日 | 2005-08-12 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.
Febs J., 272, 2005
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2AOI
 | | Crystal structure analysis of HIV-1 protease with a substrate analog P1-P6 | | 分子名称: | PEPTIDE INHIBITOR, POL POLYPROTEIN, SULFATE ION | | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | | 登録日 | 2005-08-12 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.
Febs J., 272, 2005
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3KRN
 | | Crystal Structure of C. elegans cell-death-related nuclease 5(CRN-5) | | 分子名称: | Protein C14A4.5, confirmed by transcript evidence | | 著者 | Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Chow, S.Y, Yuan, H.S. | | 登録日 | 2009-11-19 | | 公開日 | 2010-01-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.918 Å) | | 主引用文献 | Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation
Rna, 16, 2010
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3GO7
 | | Crystal Structure of M. tuberculosis ribokinase (Rv2436) in complex with ribose | | 分子名称: | MAGNESIUM ION, RIBOKINASE RBSK, alpha-D-ribofuranose | | 著者 | Masters, E.I, Sun, Y, Wang, Y, Parker, W.B, Li, R. | | 登録日 | 2009-03-18 | | 公開日 | 2010-03-31 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure and biochemical characterization of M.tuberculosis ribokinase (Rv2436)
To be Published
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