5KNR
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![BU of 5knr by Molmil](/molmil-images/mine/5knr) | E. coli HPRT in complexed with 9-[(N-phosphonoethyl-N-phosphonoethoxyethyl)-2-aminoethyl]-guanine | Descriptor: | (2-{[2-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)ethyl][2-(2-phosphonoethoxy)ethyl]amino}ethyl)phosphonic acid, Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION | Authors: | Eng, W.S, Keough, D.T, Hockova, D, Janeba, Z. | Deposit date: | 2016-06-28 | Release date: | 2017-07-19 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.864 Å) | Cite: | Crystal Structures of Acyclic Nucleoside Phosphonates in Complex with Escherichia coli Hypoxanthine Phosphoribosyltransferase Chemistryselect, 1, 2016
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5KNU
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![BU of 5knu by Molmil](/molmil-images/mine/5knu) | Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with 9-[N,N-(Bis-3-phosphonopropyl)aminomethyl]-9-deazahypoxanthine | Descriptor: | 3-[(4-oxidanylidene-3,5-dihydropyrrolo[3,2-d]pyrimidin-7-yl)methyl-(3-phosphonopropyl)amino]propylphosphonic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hypoxanthine-guanine phosphoribosyltransferase, ... | Authors: | Eng, W.S, Keough, D.T, Baszczynski, O, Hockova, D, Janeba, Z. | Deposit date: | 2016-06-28 | Release date: | 2017-07-19 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.808 Å) | Cite: | Crystal Structures of Acyclic Nucleoside Phosphonates in Complex with Escherichia coli Hypoxanthine Phosphoribosyltransferase Chemistryselect, 1, 2016
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1WPI
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![BU of 1wpi by Molmil](/molmil-images/mine/1wpi) | Solution NMR Structure of Protein YKR049C from Saccharomyces cerevisiae. Ontario Centre for Structural Proteomics target YST0250_1_133; Northeast Structural Genomics Consortium YTYst250 | Descriptor: | Hypothetical 15.6 kDa protein in NAP1-TRK2 intergenic region | Authors: | Jung, J.W, Yee, A, Arrowsmith, C.H, Lee, W, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-09-03 | Release date: | 2005-09-13 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of YKR049C, a putative redox protein from Saccharomyces cerevisiae J.Biochem.Mol.Biol., 38, 2005
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5KNX
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![BU of 5knx by Molmil](/molmil-images/mine/5knx) | Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with {[(2-[(Hypoxanthin-9H-yl)methyl]propane-1,3-diyl)bis(oxy)]bis- (methylene)}diphosphonic Acid | Descriptor: | Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION, [2-[(6-oxidanylidene-1~{H}-purin-9-yl)methyl]-3-(phosphonomethoxy)propoxy]methylphosphonic acid | Authors: | Eng, W.S, Keough, D.T, Hockova, D, Janeba, Z, Guddat, L.W. | Deposit date: | 2016-06-28 | Release date: | 2017-07-19 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structures of Acyclic Nucleoside Phosphonates in Complex with Escherichia coli Hypoxanthine Phosphoribosyltransferase Chemistryselect, 1, 2016
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4Q1S
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![BU of 4q1s by Molmil](/molmil-images/mine/4q1s) | Yeast 20S proteasome in Complex with Kendomycin | Descriptor: | (5R,6R,7S,8R,9R,12S,13E,16S,18S,19R,20aR)-4,7,19-trihydroxy-2,6,8,12,14,16,18-heptamethyl-6,7,8,9,10,11,12,15,16,17,18,19,20,20a-tetradecahydro-1,19:5,9-diepoxybenzo[18]annulen-3(5H)-one, Probable proteasome subunit alpha type-7, Proteasome subunit alpha type-1, ... | Authors: | Beck, P, Heinemeyer, W, Spaeth, A, Elnakady, Y, Mueller, R, Groll, M. | Deposit date: | 2014-04-04 | Release date: | 2014-07-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Interactions of the natural product kendomycin and the 20S proteasome. J.Mol.Biol., 426, 2014
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3LPD
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![BU of 3lpd by Molmil](/molmil-images/mine/3lpd) | Crystal structure of a subtilisin-like protease | Descriptor: | Acidic extracellular subtilisin-like protease AprV2, CALCIUM ION | Authors: | Porter, C.J, Wong, W, Whisstock, J.C, Rood, J.I, Kennan, R.M. | Deposit date: | 2010-02-05 | Release date: | 2010-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates Plos Pathog., 6, 2010
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1R9L
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![BU of 1r9l by Molmil](/molmil-images/mine/1r9l) | structure analysis of ProX in complex with glycine betaine | Descriptor: | Glycine betaine-binding periplasmic protein, TRIMETHYL GLYCINE, UNKNOWN ATOM OR ION | Authors: | Schiefner, A, Breed, J, Bosser, L, Kneip, S, Gade, J, Holtmann, G, Diederichs, K, Welte, W, Bremer, E. | Deposit date: | 2003-10-30 | Release date: | 2004-02-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Cation-pi Interactions as Determinants for Binding of the Compatible Solutes Glycine Betaine and Proline Betaine by the Periplasmic Ligand-binding Protein ProX from Escherichia coli J.BIOL.CHEM., 279, 2004
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3LQ4
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![BU of 3lq4 by Molmil](/molmil-images/mine/3lq4) | E. coli pyruvate dehydrogenase complex E1 E235A mutant with high TDP concentration | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Furey, W. | Deposit date: | 2010-02-08 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Communication between thiamin cofactors in the Escherichia coli pyruvate dehydrogenase complex E1 component active centers: evidence for a "direct pathway" between the 4'-aminopyrimidine N1' atoms. J.Biol.Chem., 285, 2010
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5ROB
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![BU of 5rob by Molmil](/molmil-images/mine/5rob) | PanDDA analysis group deposition of ground-state model of SARS-CoV-2 helicase | Descriptor: | Helicase, PHOSPHATE ION, ZINC ION | Authors: | Newman, J.A, Yosaatmadja, Y, Douangamath, A, Aimon, A, Powell, A.J, Dias, A, Fearon, D, Dunnett, L, Brandao-Neto, J, Krojer, T, Skyner, R, Gorrie-Stone, T, Thompson, W, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | Deposit date: | 2020-09-22 | Release date: | 2021-03-10 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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4PXW
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![BU of 4pxw by Molmil](/molmil-images/mine/4pxw) | Crystal structure of human DCAF1 WD40 repeats (Q1250L) | Descriptor: | Protein VPRBP, UNKNOWN ATOM OR ION | Authors: | Xu, C, Tempel, W, He, H, Li, Y, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2014-03-25 | Release date: | 2014-04-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Crystal structure of human DCAF1 WD40 repeats (Q1250L) TO BE PUBLISHED
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1RGK
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![BU of 1rgk by Molmil](/molmil-images/mine/1rgk) | RNASE T1 MUTANT GLU46GLN BINDS THE INHIBITORS 2'GMP AND 2'AMP AT THE 3' SUBSITE | Descriptor: | ADENOSINE-2'-MONOPHOSPHATE, CALCIUM ION, RIBONUCLEASE T1 | Authors: | Granzin, J, Puras-Lutzke, R, Landt, O, Grunert, H.-P, Heinemann, U, Saenger, W, Hahn, U. | Deposit date: | 1992-02-19 | Release date: | 1993-01-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | RNase T1 mutant Glu46Gln binds the inhibitors 2'GMP and 2'AMP at the 3' subsite. J.Mol.Biol., 225, 1992
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1RGQ
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![BU of 1rgq by Molmil](/molmil-images/mine/1rgq) | M9A HCV Protease complex with pentapeptide keto-amide inhibitor | Descriptor: | N-(PYRAZIN-2-YLCARBONYL)LEUCYLISOLEUCYL-N~1~-{1-[2-({1-CARBOXY-2-[4-(PHOSPHONOOXY)PHENYL]ETHYL}AMINO)-1,1-DIHYDROXY-2-OXOETHYL]BUT-3-ENYL}-3-CYCLOHEXYLALANINAMIDE, NS3 Protease, NS4A peptide, ... | Authors: | Liu, Y, Stoll, V.S, Richardson, P.L, Saldivar, A, Klaus, J.L, Molla, A, Kohlbrenner, W, Kati, W.M. | Deposit date: | 2003-11-12 | Release date: | 2004-10-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Hepatitis C NS3 protease inhibition by peptidyl-alpha-ketoamide inhibitors: kinetic mechanism and structure. Arch.Biochem.Biophys., 421, 2004
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3LXY
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![BU of 3lxy by Molmil](/molmil-images/mine/3lxy) | Crystal structure of 4-hydroxythreonine-4-phosphate dehydrogenase from Yersinia pestis CO92 | Descriptor: | 4-hydroxythreonine-4-phosphate dehydrogenase, NICKEL (II) ION, SULFATE ION, ... | Authors: | Nocek, B, Maltseva, N, Kwon, K, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-02-25 | Release date: | 2010-03-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of 4-hydroxythreonine-4-phosphate dehydrogenase from Yersinia pestis CO92 To be Published
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1RCK
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![BU of 1rck by Molmil](/molmil-images/mine/1rck) | |
2M0M
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![BU of 2m0m by Molmil](/molmil-images/mine/2m0m) | Structural Characterization of Minor Ampullate Spidroin Domains and their Distinct Roles in Fibroin Solubility and Fiber Formation | Descriptor: | Minor ampullate fibroin 1 | Authors: | Yang, D, Gao, Z, Lin, Z, Huang, W, Lai, C, Fan, J. | Deposit date: | 2012-10-30 | Release date: | 2013-03-27 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural characterization of minor ampullate spidroin domains and their distinct roles in fibroin solubility and fiber formation Plos One, 8, 2013
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1RMM
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![BU of 1rmm by Molmil](/molmil-images/mine/1rmm) | Probing the Role of Tryptophans in Aequorea Victoria Green Fluorescent Proteins with an Expanded Genetic Code | Descriptor: | SIGF1-GFP fusion protein | Authors: | Budisa, N, Pal, P.P, Alefelder, S, Birle, P, Krywcun, T, Rubini, M, Wenger, W, Bae, J.H, Steiner, T. | Deposit date: | 2003-11-28 | Release date: | 2004-06-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code Biol.Chem., 385, 2004
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3LLU
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![BU of 3llu by Molmil](/molmil-images/mine/3llu) | Crystal structure of the nucleotide-binding domain of Ras-related GTP-binding protein C | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related GTP-binding protein C, ... | Authors: | Nedyalkova, L, Tempel, W, Tong, Y, Crombet, L, Zhong, N, Guan, X, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-01-29 | Release date: | 2010-02-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of the nucleotide-binding domain of Ras-related GTP-binding protein C to be published
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1RU3
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![BU of 1ru3 by Molmil](/molmil-images/mine/1ru3) | Crystal Structure of the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans | Descriptor: | Acetyl-CoA synthase, GLYCEROL, IRON/SULFUR CLUSTER, ... | Authors: | Svetlitchnyi, V, Dobbek, H, Meyer-Klaucke, W, Meins, T, Thiele, B, Rmer, P, Huber, R, Meyer, O. | Deposit date: | 2003-12-11 | Release date: | 2003-12-23 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A functional Ni-Ni-[4Fe-4S] cluster in the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans Proc.Natl.Acad.Sci.USA, 101, 2004
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3LNM
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![BU of 3lnm by Molmil](/molmil-images/mine/3lnm) | F233W mutant of the Kv2.1 paddle-Kv1.2 chimera channel | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, F233W mutant of the Kv2.1 paddle-Kv1.2 chimera, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Tao, X, Lee, A, Limapichat, W, Dougherty, D.A, MacKinnon, R. | Deposit date: | 2010-02-02 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A gating charge transfer center in voltage sensors. Science, 328, 2010
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1X56
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![BU of 1x56 by Molmil](/molmil-images/mine/1x56) | |
8DOK
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![BU of 8dok by Molmil](/molmil-images/mine/8dok) | Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer in complex with 8ANC195 and 10-1074 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, Y, Zhou, F, Huang, R, Tolbert, W, Pazgier, M. | Deposit date: | 2022-07-13 | Release date: | 2023-07-19 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
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4Q94
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![BU of 4q94 by Molmil](/molmil-images/mine/4q94) | human RPRD1B CID in complex with a RPB1-CTD derived Ser2 phosphorylated peptide | Descriptor: | Regulation of nuclear pre-mRNA domain-containing protein 1B, SULFATE ION, UNKNOWN ATOM OR ION, ... | Authors: | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | Deposit date: | 2014-04-29 | Release date: | 2014-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
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1RTS
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![BU of 1rts by Molmil](/molmil-images/mine/1rts) | THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX | Authors: | Sotelo-Mundo, R.R, Ciesla, J, Dzik, J.M, Rode, W, Maley, F, Maley, G, Hardy, L.W, Montfort, W.R. | Deposit date: | 1998-06-19 | Release date: | 1999-02-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug. Biochemistry, 38, 1999
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1R8G
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![BU of 1r8g by Molmil](/molmil-images/mine/1r8g) | Structure and function of YbdK | Descriptor: | Hypothetical protein ybdK | Authors: | Lehmann, C, Doseeva, V, Pullalarevu, S, Krajewski, W, Howard, A, Herzberg, O, Structure 2 Function Project (S2F) | Deposit date: | 2003-10-24 | Release date: | 2004-08-17 | Last modified: | 2021-07-28 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | YbdK is a carboxylate-amine ligase with a gamma-glutamyl:Cysteine ligase activity: crystal structure and enzymatic assays PROTEINS: STRUCT.,FUNCT.,GENET., 56, 2004
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1RQ6
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![BU of 1rq6 by Molmil](/molmil-images/mine/1rq6) | Solution structure of ribosomal protein S17E from Methanobacterium Thermoautotrophicum, Northeast Structural Genomics Consortium Target TT802 / Ontario Center for Structural Proteomics Target Mth0803 | Descriptor: | 30S ribosomal protein S17e | Authors: | Wu, B, Yee, A, Huang, Y.J, Ramelot, T.A, Semesi, A, Jung, J.W, Edward, A, Lee, W, Kennedy, M.A, Montelione, G.T, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-12-04 | Release date: | 2004-12-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The solution structure of ribosomal protein S17E from Methanobacterium thermoautotrophicum: a structural homolog of the FF domain. Protein Sci., 17, 2008
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