5KG1
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2WQ5
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![BU of 2wq5 by Molmil](/molmil-images/mine/2wq5) | Non-antibiotic properties of tetracyclines: structural basis for inhibition of secretory phospholipase A2. | Descriptor: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, CALCIUM ION, PHOSPHOLIPASE A2, ... | Authors: | Dalm, D, Palm, G.J, Hinrichs, W. | Deposit date: | 2009-08-13 | Release date: | 2010-03-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Non-Antibiotic Properties of Tetracyclines: Structural Basis for Inhibition of Secretory Phospholipase A(2). J.Mol.Biol., 398, 2010
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5K9V
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![BU of 5k9v by Molmil](/molmil-images/mine/5k9v) | Protein Tyrosine Phosphatase 1B (1-301), open state | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Choy, M.S, Peti, W, Page, R. | Deposit date: | 2016-06-01 | Release date: | 2017-03-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.898 Å) | Cite: | Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery. Mol. Cell, 65, 2017
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5KAA
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![BU of 5kaa by Molmil](/molmil-images/mine/5kaa) | Protein Tyrosine Phosphatase 1B Delta helix 7, P185G mutant, open state | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Choy, M.S, Machado, L.E.S.F, Peti, W, Page, R. | Deposit date: | 2016-06-01 | Release date: | 2017-03-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.968 Å) | Cite: | Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery. Mol. Cell, 65, 2017
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5K4I
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![BU of 5k4i by Molmil](/molmil-images/mine/5k4i) | Crystal Structure of ERK2 in complex with compound 22 | Descriptor: | 1,2-ETHANEDIOL, 1-[(1~{S})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one, Mitogen-activated protein kinase 1 | Authors: | Yin, J, Wang, W. | Deposit date: | 2016-05-20 | Release date: | 2016-07-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development. J.Med.Chem., 59, 2016
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5K6S
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![BU of 5k6s by Molmil](/molmil-images/mine/5k6s) | The structure of the PP2A B56 subunit BubR1 complex | Descriptor: | BubR1, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | Authors: | Page, R, Wang, X, Bajaj, R, Peti, W. | Deposit date: | 2016-05-25 | Release date: | 2016-12-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.794 Å) | Cite: | Expanding the PP2A Interactome by Defining a B56-Specific SLiM. Structure, 24, 2016
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2EPS
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![BU of 2eps by Molmil](/molmil-images/mine/2eps) | Solution structure of the 4th zinc finger domain of Zinc finger protein 278 | Descriptor: | POZ-, AT hook-, and zinc finger-containing protein 1, ... | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the 4th zinc finger domain of Zinc finger protein 278 To be Published
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5K7Z
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![BU of 5k7z by Molmil](/molmil-images/mine/5k7z) | Crystal structure of AibR in complex with isovaleryl coenzyme A and operator DNA | Descriptor: | DNA (32-MER), Isovaleryl-coenzyme A, Transcriptional regulator, ... | Authors: | Bock, T, Volz, C, Mueller, R, Blankenfeldt, W. | Deposit date: | 2016-05-27 | Release date: | 2016-12-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Crystal structure of AibR in complex with isovaleryl coenzyme A and operator DNA to be published
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5KG6
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![BU of 5kg6 by Molmil](/molmil-images/mine/5kg6) | |
5KFG
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![BU of 5kfg by Molmil](/molmil-images/mine/5kfg) | |
5KFR
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![BU of 5kfr by Molmil](/molmil-images/mine/5kfr) | |
5JPE
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![BU of 5jpe by Molmil](/molmil-images/mine/5jpe) | Yeast-specific serine/threonine protein phosphatase (PPZ1) of Candida albicans | Descriptor: | CITRATE ANION, GLYCEROL, Serine/threonine-protein phosphatase | Authors: | Choy, M.S, Chen, E.H, Peti, W, Page, R. | Deposit date: | 2016-05-03 | Release date: | 2016-08-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.611 Å) | Cite: | Molecular Insights into the Fungus-Specific Serine/Threonine Protein Phosphatase Z1 in Candida albicans. Mbio, 7, 2016
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5KG4
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![BU of 5kg4 by Molmil](/molmil-images/mine/5kg4) | |
2EQO
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![BU of 2eqo by Molmil](/molmil-images/mine/2eqo) | Solution structure of the stn_TRAF3IP1_nd domain of interleukin 13 receptor alpha 1-binding protein-1 [Homo sapiens] | Descriptor: | TNF receptor-associated factor 3-interacting protein 1 | Authors: | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the stn_TRAF3IP1_nd domain of interleukin 13 receptor alpha 1-binding protein-1 [Homo sapiens] To be Published
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1AU8
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![BU of 1au8 by Molmil](/molmil-images/mine/1au8) | HUMAN CATHEPSIN G | Descriptor: | CATHEPSIN G, N-(3-carboxypropanoyl)-L-valyl-N-[(1R)-5-amino-1-phosphonopentyl]-L-prolinamide | Authors: | Medrano, F.J, Bode, W, Banbula, A, Potempa, J. | Deposit date: | 1997-09-12 | Release date: | 1998-10-14 | Last modified: | 2012-12-12 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | HUMAN CATHEPSIN G to be published
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2EPV
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![BU of 2epv by Molmil](/molmil-images/mine/2epv) | Solution structure of the 20th C2H2 type zinc finger domain of Zinc finger protein 268 | Descriptor: | ZINC ION, Zinc finger protein 268 | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the 20th C2H2 type zinc finger domain of Zinc finger protein 268 To be Published
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2EQ1
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![BU of 2eq1 by Molmil](/molmil-images/mine/2eq1) | Solution structure of the 9th C2H2 type zinc finger domain of Zinc finger protein 347 | Descriptor: | ZINC ION, Zinc finger protein 347 | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the 9th C2H2 type zinc finger domain of Zinc finger protein 347 To be Published
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2EQJ
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![BU of 2eqj by Molmil](/molmil-images/mine/2eqj) | Solution structure of the TUDOR domain of Metal-response element-binding transcription factor 2 | Descriptor: | Metal-response element-binding transcription factor 2 | Authors: | Dang, W, Muto, Y, Isono, K, Watanabe, S, Tarada, T, Kigawa, T, Koseki, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2008-04-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the TUDOR domain of Metal-response element-binding transcription factor 2 To be Published
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2EPU
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![BU of 2epu by Molmil](/molmil-images/mine/2epu) | Solution structure of the secound C2H2 type zinc finger domain of Zinc finger protein 32 | Descriptor: | ZINC ION, Zinc finger protein 32 | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the secound C2H2 type zinc finger domain of Zinc finger protein 32 To be Published
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2EQ2
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![BU of 2eq2 by Molmil](/molmil-images/mine/2eq2) | Solution structure of the 16th C2H2 type zinc finger domain of Zinc finger protein 347 | Descriptor: | ZINC ION, Zinc finger protein 347 | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the 16th C2H2 type zinc finger domain of Zinc finger protein 347 To be Published
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2EQK
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![BU of 2eqk by Molmil](/molmil-images/mine/2eqk) | Solution structure of the TUDOR domain of Tudor domain-containing protein 4 | Descriptor: | Tudor domain-containing protein 4 | Authors: | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the TUDOR domain of Tudor domain-containing protein 4 To be Published
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2EPD
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![BU of 2epd by Molmil](/molmil-images/mine/2epd) | Solution structure of SH3 domain in Rho-GTPase-activating protein 4 | Descriptor: | Rho GTPase-activating protein 4 | Authors: | Tanabe, W, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-29 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of SH3 domain in Rho-GTPase-activating protein 4 To be Published
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2EPT
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![BU of 2ept by Molmil](/molmil-images/mine/2ept) | Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 32 | Descriptor: | ZINC ION, Zinc finger protein 32 | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 32 To be Published
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2EPX
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![BU of 2epx by Molmil](/molmil-images/mine/2epx) | Solution structure of the third C2H2 type zinc finger domain of Zinc finger protein 28 homolog | Descriptor: | ZINC ION, Zinc finger protein 28 homolog | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the third C2H2 type zinc finger domain of Zinc finger protein 28 homolog To be Published
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5K0K
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![BU of 5k0k by Molmil](/molmil-images/mine/5k0k) | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC2434 | Descriptor: | 15-{4-[(4-methylpiperazin-1-yl)methyl]phenyl}-4,5,6,7,9,10,11,12-octahydro-2,16-(azenometheno)pyrrolo[2,1-d][1,3,5,9]te traazacyclotetradecin-8(3H)-one, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Wang, X, Liu, J, Zhang, W, Stashko, M.A, Nichols, J, DeRyckere, D, Miley, M.J, Norris-Drouin, J, Chen, Z, Machius, M, Wood, E, Graham, D.K, Earp, H.S, Graham, K, Kireev, D, Frye, S.V. | Deposit date: | 2016-05-17 | Release date: | 2017-01-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.545 Å) | Cite: | Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors. ACS Med Chem Lett, 7, 2016
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