5JGK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jgk by Molmil](/molmil-images/mine/5jgk) | Crystal structure of GtmA in complex with SAH | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, UbiE/COQ5 family methyltransferase, ... | Authors: | Dolan, S.K, Bock, T, Hering, V, Jones, G.W, Blankenfeldt, W, Dolye, S. | Deposit date: | 2016-04-20 | Release date: | 2017-03-01 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Structural, mechanistic and functional insight into gliotoxinbis-thiomethylation inAspergillus fumigatus. Open Biol, 7, 2017
|
|
7TNT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tnt by Molmil](/molmil-images/mine/7tnt) | The tubulin-based conoid from detergent-extract Toxoplasma gondii cells | Descriptor: | Tubulin alpha chain, Tubulin beta chain | Authors: | Sun, S.Y, Pintilie, G.D, Chen, M, Chiu, W. | Deposit date: | 2022-01-21 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7TNS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tns by Molmil](/molmil-images/mine/7tns) | Subpellicular microtubule from detergent-extract Toxoplasma gondii cells | Descriptor: | Microtubule associated protein SPM1, PDI family protein, Tubulin alpha chain, ... | Authors: | Sun, S.Y, Pintilie, G.D, Chen, M, Chiu, W. | Deposit date: | 2022-01-21 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
1CQ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cq0 by Molmil](/molmil-images/mine/1cq0) | SOLUTION STRUCTURE OF A HUMAN HYPOCRETIN-2/OREXIN-B'SOLUTION STRUCTURE OF A HUMAN HYPOCRETIN-2/OREXIN-B ' | Descriptor: | PROTEIN (NEW HYPOTHALAMIC NEUROPEPTIDE/OREXIN-B28) | Authors: | Lee, K.-H, Bang, E.J, Chae, K.-J, Lee, D.W, Lee, W. | Deposit date: | 1999-08-04 | Release date: | 2000-01-10 | Last modified: | 2024-04-10 | Method: | SOLUTION NMR | Cite: | Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B. Eur.J.Biochem., 266, 1999
|
|
1EDO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1edo by Molmil](/molmil-images/mine/1edo) | THE X-RAY STRUCTURE OF BETA-KETO ACYL CARRIER PROTEIN REDUCTASE FROM BRASSICA NAPUS COMPLEXED WITH NADP+ | Descriptor: | BETA-KETO ACYL CARRIER PROTEIN REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Fisher, M, Kroon, J.T, Martindale, W, Stuitje, A.R, Slabas, A.R, Rafferty, J.B. | Deposit date: | 2000-01-28 | Release date: | 2001-01-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The X-ray structure of Brassica napus beta-keto acyl carrier protein reductase and its implications for substrate binding and catalysis. Structure Fold.Des., 8, 2000
|
|
1EAP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1eap by Molmil](/molmil-images/mine/1eap) | CRYSTAL STRUCTURE OF A CATALYTIC ANTIBODY WITH A SERINE PROTEASE ACTIVE SITE | Descriptor: | IGG2B-KAPPA 17E8 FAB (HEAVY CHAIN), IGG2B-KAPPA 17E8 FAB (LIGHT CHAIN), PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE | Authors: | Zhou, G.W, Guo, J, Huang, W, Scanlan, T.S, Fletterick, R.J. | Deposit date: | 1994-08-10 | Release date: | 1994-12-20 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of a catalytic antibody with a serine protease active site. Science, 265, 1994
|
|
2AGP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2agp by Molmil](/molmil-images/mine/2agp) | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*(DOC)-3'), ... | Authors: | Ling, H, Yang, W. | Deposit date: | 2005-07-27 | Release date: | 2005-09-06 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. Embo J., 24, 2005
|
|
2WFV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wfv by Molmil](/molmil-images/mine/2wfv) | Crystal structure of DILP5 variant C4 | Descriptor: | PROBABLE INSULIN-LIKE PEPTIDE 5 A CHAIN, PROBABLE INSULIN-LIKE PEPTIDE 5 B CHAIN | Authors: | Kulahin, N, Schluckebier, G, Sajid, W, De Meyts, P. | Deposit date: | 2009-04-15 | Release date: | 2010-05-26 | Last modified: | 2012-04-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and Biological Properties of the Drosophila Insulin-Like Peptide 5 Show Evolutionary Conservation. J.Biol.Chem., 286, 2011
|
|
2AHG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ahg by Molmil](/molmil-images/mine/2ahg) | Unsaturated glucuronyl hydrolase mutant D88N with dGlcA-GalNAc | Descriptor: | 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, unsaturated glucuronyl hydrolase | Authors: | Itoh, T, Hashimoto, W, Mikami, B, Murata, K. | Deposit date: | 2005-07-28 | Release date: | 2006-08-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of Unsaturated Glucuronyl Hydrolase Complexed with Substrate: MOLECULAR INSIGHTS INTO ITS CATALYTIC REACTION MECHANISM J.Biol.Chem., 281, 2006
|
|
5IWE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5iwe by Molmil](/molmil-images/mine/5iwe) | E45Q mutant of phenazine biosynthesis protein PhzF in complex with (5R,6R)-6-azaniumyl-5-ethoxycyclohexa-1,3-diene-1-carboxylate | Descriptor: | (5R,6R)-6-azaniumyl-5-ethoxycyclohexa-1,3-diene-1-carboxylate, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Diederich, C, Blankenfeldt, W. | Deposit date: | 2016-03-22 | Release date: | 2017-03-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Mechanisms and Specificity of Phenazine Biosynthesis Protein PhzF. Sci Rep, 7, 2017
|
|
2W35
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2w35 by Molmil](/molmil-images/mine/2w35) | Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair | Descriptor: | 5'-D(*AP*GP*CP*CP*GP*TP)-3', 5'-D(*AP*TP*GP*CP*GP*AP*CP*IP*GP)-3', Endonuclease V, ... | Authors: | Dalhus, B, Arvai, A.S, Rosnes, I, Olsen, O.E, Backe, P.H, Alseth, I, Gao, H, Cao, W, Tainer, J.A, Bjoras, M. | Deposit date: | 2008-11-06 | Release date: | 2009-01-20 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structures of Endonuclease V with DNA Reveal Initiation of Deaminated Adenine Repair. Nat.Struct.Mol.Biol., 16, 2009
|
|
2AQU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2aqu by Molmil](/molmil-images/mine/2aqu) | Structure of HIV-1 protease bound to atazanavir | Descriptor: | (3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5, 6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER, HIV-1 Protease | Authors: | Clemente, J.C, Coman, R.M, Thiaville, M.M, Janka, L.K, Jeung, J.A, Nukoolkarn, S, Govindasamy, L, Agbandje-McKenna, M, McKenna, R, Leelamanit, W, Goodenow, M.M, Dunn, B.M. | Deposit date: | 2005-08-18 | Release date: | 2006-08-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir. Biochemistry, 45, 2006
|
|
2WBX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wbx by Molmil](/molmil-images/mine/2wbx) | Crystal structure of mouse cadherin-23 EC1 | Descriptor: | CADHERIN-23, CALCIUM ION | Authors: | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | Deposit date: | 2009-03-05 | Release date: | 2010-04-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Determinants of Cadherin-23 Function in Hearing and Deafness. Neuron, 66, 2010
|
|
1CS6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cs6 by Molmil](/molmil-images/mine/1cs6) | N-TERMINAL FRAGMENT OF AXONIN-1 FROM CHICKEN | Descriptor: | AXONIN-1, GLYCEROL | Authors: | Freigang, J, Proba, K, Diederichs, K, Sonderegger, P, Welte, W. | Deposit date: | 1999-08-17 | Release date: | 2000-05-19 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of the ligand binding module of axonin-1/TAG-1 suggests a zipper mechanism for neural cell adhesion. Cell(Cambridge,Mass.), 101, 2000
|
|
5J41
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5j41 by Molmil](/molmil-images/mine/5j41) | Glutathione S-transferase bound with hydrolyzed Piperlongumine | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-(3,4,5-trimethoxyphenyl)propanoic acid, GLUTATHIONE, ... | Authors: | Harshbarger, W, Gondi, S, Ficarro, S, Hunter, J, Udayakumar, D, Gurbani, D, Marto, J, Westover, K. | Deposit date: | 2016-03-31 | Release date: | 2016-11-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.19035351 Å) | Cite: | Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine. J. Biol. Chem., 292, 2017
|
|
1CT4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ct4 by Molmil](/molmil-images/mine/1ct4) | CRYSTAL STRUCTURE OF THE OMTKY3 P1 VARIANT OMTKY3-VAL18I IN COMPLEX WITH SGPB | Descriptor: | OVOMUCOID INHIBITOR, PROTEINASE B | Authors: | Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | Deposit date: | 1999-08-18 | Release date: | 2000-01-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Deleterious effects of beta-branched residues in the S1 specificity pocket of Streptomyces griseus proteinase B (SGPB): crystal structures of the turkey ovomucoid third domain variants Ile18I, Val18I, Thr18I, and Ser18I in complex with SGPB. Protein Sci., 9, 2000
|
|
2WVO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wvo by Molmil](/molmil-images/mine/2wvo) | Structure of the HET-S N-terminal domain | Descriptor: | CHLORIDE ION, SMALL S PROTEIN | Authors: | Greenwald, J, Buhtz, C, Ritter, C, Kwiatkowski, W, Choe, S, Saupe, S.J, Riek, R. | Deposit date: | 2009-10-19 | Release date: | 2010-07-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Mechanism of Prion Inhibition by Het-S. Mol.Cell, 38, 2010
|
|
1JIV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jiv by Molmil](/molmil-images/mine/1jiv) | T4 phage BGT in complex with Mg2+ : Form II | Descriptor: | DNA BETA-GLUCOSYLTRANSFERASE, MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE | Authors: | Morera, S, Lariviere, L, Kurzeck, J, Aschke-Sonnenborn, U, Freemont, P.S, Janin, J, Ruger, W. | Deposit date: | 2001-07-03 | Release date: | 2001-08-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | High resolution crystal structures of T4 phage beta-glucosyltransferase: induced fit and effect of substrate and metal binding. J.Mol.Biol., 311, 2001
|
|
1CWY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cwy by Molmil](/molmil-images/mine/1cwy) | CRYSTAL STRUCTURE OF AMYLOMALTASE FROM THERMUS AQUATICUS, A GLYCOSYLTRANSFERASE CATALYSING THE PRODUCTION OF LARGE CYCLIC GLUCANS | Descriptor: | AMYLOMALTASE | Authors: | Przylas, I, Tomoo, K, Terada, Y, Takaha, T, Fuji, K, Saenger, W, Straeter, N. | Deposit date: | 1999-08-27 | Release date: | 2001-02-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of amylomaltase from thermus aquaticus, a glycosyltransferase catalysing the production of large cyclic glucans. J.Mol.Biol., 296, 2000
|
|
1JJ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jj9 by Molmil](/molmil-images/mine/1jj9) | Crystal Structure of MMP8-Barbiturate Complex Reveals Mechanism for Collagen Substrate Recognition | Descriptor: | 2-HYDROXY-5-[4-(2-HYDROXY-ETHYL)-PIPERIDIN-1-YL]-5-PHENYL-1H-PYRIMIDINE-4,6-DIONE, CALCIUM ION, Matrix Metalloproteinase 8, ... | Authors: | Brandstetter, H, Grams, F, Glitz, D, Lang, A, Huber, R, Bode, W, Krell, H.-W, Engh, R.A. | Deposit date: | 2001-07-04 | Release date: | 2001-08-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 1.8-A crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition. J.Biol.Chem., 276, 2001
|
|
2B2T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b2t by Molmil](/molmil-images/mine/2b2t) | Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and phosphothreonine 3 | Descriptor: | Chromodomain-helicase-DNA-binding protein 1, Histone H3 tail | Authors: | Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S. | Deposit date: | 2005-09-19 | Release date: | 2005-12-27 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Double chromodomains cooperate to recognize the methylated histone H3 tail. Nature, 438, 2005
|
|
1CZ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cz5 by Molmil](/molmil-images/mine/1cz5) | NMR STRUCTURE OF VAT-N: THE N-TERMINAL DOMAIN OF VAT (VCP-LIKE ATPASE OF THERMOPLASMA) | Descriptor: | VCP-LIKE ATPASE | Authors: | Coles, M, Diercks, T, Liermann, J, Groeger, A, Rockel, B, Baumeister, W, Koretke, K, Lupas, A, Peters, J, Kessler, H. | Deposit date: | 1999-09-01 | Release date: | 1999-10-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The solution structure of VAT-N reveals a 'missing link' in the evolution of complex enzymes from a simple betaalphabetabeta element. Curr.Biol., 9, 1999
|
|
2X7R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2x7r by Molmil](/molmil-images/mine/2x7r) | |
5K02
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k02 by Molmil](/molmil-images/mine/5k02) | Structure of human SOD1 with T2D mutation | Descriptor: | COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Fay, J.M, Zhu, C, Cui, W, Ke, H, Dokholyan, N.V. | Deposit date: | 2016-05-17 | Release date: | 2016-11-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an ALS-Associated Mutation. Structure, 24, 2016
|
|
2CP8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cp8 by Molmil](/molmil-images/mine/2cp8) | Solution structure of the RSGI RUH-046, a UBA domain from human Next to BRCA1 gene 1 protein (KIAA0049 protein) R923H variant | Descriptor: | Next to BRCA1 gene 1 protein | Authors: | Ohashi, W, Hirota, H, Yamazaki, T, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-19 | Release date: | 2005-11-19 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the RSGI RUH-046, a UBA domain from human Next to BRCA1 gene 1 protein (KIAA0049 protein) R923H variant To be Published
|
|