5JGK

Crystal structure of GtmA in complex with SAH

Summary for 5JGK

DescriptorUbiE/COQ5 family methyltransferase, putative, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... (4 entities in total)
Functional Keywordsaspergillus fumigatus, methyltransferase, s-adenosyl-l-homocysteine, gliotoxin, resistance, transferase
Biological sourceAspergillus fumigatus Z5
Total number of polymer chains2
Total molecular weight66160.96
Authors
Dolan, S.K.,Bock, T.,Hering, V.,Jones, G.W.,Blankenfeldt, W.,Dolye, S. (deposition date: 2016-04-20, release date: 2017-03-01, Last modification date: 2018-03-28)
Primary citation
Dolan, S.K.,Bock, T.,Hering, V.,Owens, R.A.,Jones, G.W.,Blankenfeldt, W.,Doyle, S.
Structural, mechanistic and functional insight into gliotoxinbis-thiomethylation inAspergillus fumigatus.
Open Biol, 7:-, 2017
PubMed: 28179499 (PDB entries with the same primary citation)
DOI: 10.1098/rsob.160292
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.33 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.167200.9%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution