6RLM
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![BU of 6rlm by Molmil](/molmil-images/mine/6rlm) | Crystal structure of AT1412dm Fab fragment | 分子名称: | AT1412dm Fab (Heavy Chain), AT1412dm Fab (Light Chain), CHLORIDE ION | 著者 | Neviani, V, Pearce, N.M, Pos, W, Schotte, R, Spits, H, Gros, P. | 登録日 | 2019-05-02 | 公開日 | 2021-05-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis of a homo-dimerization site in tetraspanin CD9 targeted by a melanoma patient-derived antibody To Be Published
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6RLO
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![BU of 6rlo by Molmil](/molmil-images/mine/6rlo) | Crystal structure of AT1412dm Fab fragment in complex with CD9 large extracellular loop | 分子名称: | AT1412dm Fab Fragment (Heavy Chain), AT1412dm Fab Fragment (Light Chain), CD9 antigen, ... | 著者 | Neviani, V, Pearce, N.M, Pos, W, Schotte, R, Spits, H, Gros, P. | 登録日 | 2019-05-02 | 公開日 | 2021-05-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis of a homo-dimerization site in tetraspanin CD9 targeted by a melanoma patient-derived antibody To Be Published
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6JM5
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![BU of 6jm5 by Molmil](/molmil-images/mine/6jm5) | Crystal structure of TBC1D23 C terminal domain | 分子名称: | SODIUM ION, TBC1 domain family member 23 | 著者 | Sun, Q, Huang, W. | 登録日 | 2019-03-07 | 公開日 | 2019-10-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural and functional studies of TBC1D23 C-terminal domain provide a link between endosomal trafficking and PCH. Proc.Natl.Acad.Sci.USA, 116, 2019
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5QPM
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![BU of 5qpm by Molmil](/molmil-images/mine/5qpm) | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000500a | 分子名称: | 1-(4-fluorophenyl)-3-(3-hydroxyphenyl)urea, ACETATE ION, Farnesyl diphosphate synthase, ... | 著者 | Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. | 登録日 | 2019-03-12 | 公開日 | 2020-04-29 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published
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5QQB
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![BU of 5qqb by Molmil](/molmil-images/mine/5qqb) | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOOA000676a | 分子名称: | 8-fluoranyl-5-methyl-1,2,3,6-tetrahydro-1,5-benzodiazocin-4-one, ACETATE ION, Farnesyl diphosphate synthase, ... | 著者 | Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. | 登録日 | 2019-03-12 | 公開日 | 2020-04-29 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published
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5QPG
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![BU of 5qpg by Molmil](/molmil-images/mine/5qpg) | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000291a | 分子名称: | 3-(azepan-1-ylmethyl)-1~{H}-indole, ACETATE ION, Farnesyl diphosphate synthase, ... | 著者 | Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. | 登録日 | 2019-03-12 | 公開日 | 2020-04-29 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published
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5QR1
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![BU of 5qr1 by Molmil](/molmil-images/mine/5qr1) | PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z396380540 | 分子名称: | 5-aminolevulinate synthase, erythroid-specific, mitochondrial, ... | 著者 | Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. | 登録日 | 2019-05-22 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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5QPV
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![BU of 5qpv by Molmil](/molmil-images/mine/5qpv) | PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000416a | 分子名称: | (2~{S})-~{N}-(4-aminocarbonylphenyl)oxolane-2-carboxamide, Farnesyl diphosphate synthase, SULFATE ION, ... | 著者 | Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. | 登録日 | 2019-03-12 | 公開日 | 2020-04-29 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published
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5QQQ
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![BU of 5qqq by Molmil](/molmil-images/mine/5qqq) | PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z2856434857 | 分子名称: | 3-[(thiomorpholin-4-yl)methyl]phenol, 5-aminolevulinate synthase, erythroid-specific, ... | 著者 | Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. | 登録日 | 2019-05-22 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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5QRA
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![BU of 5qra by Molmil](/molmil-images/mine/5qra) | PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z1101755952 | 分子名称: | 5-aminolevulinate synthase, erythroid-specific, mitochondrial, ... | 著者 | Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. | 登録日 | 2019-05-22 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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6F87
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![BU of 6f87 by Molmil](/molmil-images/mine/6f87) | Crystal structure of P. abyssi Sua5 complexed with L-threonine and PPi | 分子名称: | PYROPHOSPHATE 2-, THREONINE, Threonylcarbamoyl-AMP synthase | 著者 | Pichard-Kostuch, A, Zhang, W, Liger, D, Daugeron, M.C, Letoquart, J, Li de la Sierra-Gallay, I, Forterre, P, Collinet, B, van Tilbeurgh, H, Basta, T. | 登録日 | 2017-12-12 | 公開日 | 2018-04-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification. RNA, 24, 2018
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4PZ9
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![BU of 4pz9 by Molmil](/molmil-images/mine/4pz9) | The native structure of mycobacterial glucosyl-3-phosphoglycerate phosphatase Rv2419c | 分子名称: | Glucosyl-3-phosphoglycerate phosphatase | 著者 | Zhou, W.H, Zheng, Q.Q, Jiang, D.Q, Zhang, W, Zhang, Q.Q, Jin, J, Li, X, Yang, H.T, Shaw, N, Rao, Z. | 登録日 | 2014-03-28 | 公開日 | 2014-06-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Mechanism of dephosphorylation of glucosyl-3-phosphoglycerate by a histidine phosphatase J.Biol.Chem., 289, 2014
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1ZZT
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![BU of 1zzt by Molmil](/molmil-images/mine/1zzt) | Bovine eNOS N368D/V106M double mutant with L-N(omega)-Nitroarginine-(4R)-Amino-L-Proline Amide Bound | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE, ... | 著者 | Li, H, Flinspach, M.L, Igarashi, J, Jamal, J, Yang, W, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L. | 登録日 | 2005-06-14 | 公開日 | 2005-12-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases. Biochemistry, 44, 2005
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2SGQ
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![BU of 2sgq by Molmil](/molmil-images/mine/2sgq) | GLN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5 | 分子名称: | Ovomucoid, PHOSPHATE ION, Streptogrisin B | 著者 | Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G. | 登録日 | 1999-03-25 | 公開日 | 2003-08-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's To be Published
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6SF3
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6SF2
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![BU of 6sf2 by Molmil](/molmil-images/mine/6sf2) | Ternary complex of human bone morphogenetic protein 9 (BMP9) growth factor domain, its prodomain and extracellular domain of activin receptor-like kinase 1 (ALK1). | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Growth/differentiation factor 2, Serine/threonine-protein kinase receptor R3 | 著者 | Salmon, R.M, Guo, J, Yu, M, Li, W. | 登録日 | 2019-07-31 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms. Nat Commun, 11, 2020
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6FHP
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![BU of 6fhp by Molmil](/molmil-images/mine/6fhp) | DAIP in complex with a C-terminal fragment of thermolysin | 分子名称: | Dispase autolysis-inducing protein, Thermolysin | 著者 | Schmelz, S, Fiebig, D, Fuchsbauer, H.L, Blankenfeldt, W, Scrima, A. | 登録日 | 2018-01-15 | 公開日 | 2018-09-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.703 Å) | 主引用文献 | Destructive twisting of neutral metalloproteases: the catalysis mechanism of the Dispase autolysis-inducing protein from Streptomyces mobaraensis DSM 40487. FEBS J., 285, 2018
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5O2U
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![BU of 5o2u by Molmil](/molmil-images/mine/5o2u) | Llama VHH in complex with p24 | 分子名称: | Capsid protein p24, VHH 59H10 | 著者 | Caillat, C, Verrips, T, Weissenhorn, W. | 登録日 | 2017-05-22 | 公開日 | 2017-06-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Unravelling the Molecular Basis of High Affinity Nanobodies against HIV p24: In Vitro Functional, Structural, and in Silico Insights. ACS Infect Dis, 3, 2017
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8CH7
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![BU of 8ch7 by Molmil](/molmil-images/mine/8ch7) | RDC-refined Interleukin-4 (wild type) pH 5.6 | 分子名称: | Interleukin-4 | 著者 | Vaz, D.C, Rodrigues, J.R, Loureiro-Ferreira, N, Mueller, T, Sebald, W, Redfield, C, Brito, R.M.M. | 登録日 | 2023-02-07 | 公開日 | 2023-10-18 | 最終更新日 | 2024-01-17 | 実験手法 | SOLUTION NMR | 主引用文献 | Lessons on protein structure from interleukin-4: All disulfides are not created equal. Proteins, 92, 2024
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8CGF
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![BU of 8cgf by Molmil](/molmil-images/mine/8cgf) | Interleukin-4 (wild type) pH 2.4 | 分子名称: | Interleukin-4 | 著者 | Vaz, D.C, Rodrigues, J.R, Loureiro-Ferreira, N, Mueller, T, Sebald, W, Redfield, C, Brito, R.M.M. | 登録日 | 2023-02-04 | 公開日 | 2023-10-18 | 最終更新日 | 2024-01-17 | 実験手法 | SOLUTION NMR | 主引用文献 | Lessons on protein structure from interleukin-4: All disulfides are not created equal. Proteins, 92, 2024
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5OBZ
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![BU of 5obz by Molmil](/molmil-images/mine/5obz) | low resolution structure of the p34ct/p44ct minimal complex | 分子名称: | Putative transcription factor, ZINC ION | 著者 | Schoenwetter, E, Koelmel, W, Schmitt, D.R, Kuper, J, Kisker, C. | 登録日 | 2017-06-29 | 公開日 | 2017-10-18 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | The intricate network between the p34 and p44 subunits is central to the activity of the transcription/DNA repair factor TFIIH. Nucleic Acids Res., 45, 2017
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5YMV
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![BU of 5ymv by Molmil](/molmil-images/mine/5ymv) | Crystal structure of 9-mer peptide from influenza virus in complex with BF2*1201 | 分子名称: | ALA-VAL-LYS-GLY-VAL-GLY-THR-MET-VAL, Beta-2-microglobulin, Class I histocompatibility antigen, ... | 著者 | Xiao, J, Xiang, W, Qi, J, Chai, Y, Liu, W.J, Gao, G.F. | 登録日 | 2017-10-22 | 公開日 | 2018-10-24 | 最終更新日 | 2019-07-31 | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | 主引用文献 | An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I. J Immunol., 201, 2018
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6EZR
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6SF1
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![BU of 6sf1 by Molmil](/molmil-images/mine/6sf1) | Bone morphogenetic protein 10 (BMP10) complexed with extracellular domain of activin receptor-like kinase 1 (ALK1). | 分子名称: | Bone morphogenetic protein 10, NICKEL (II) ION, Serine/threonine-protein kinase receptor R3 | 著者 | Salmon, R.M, Guo, J, Yu, M, Li, W. | 登録日 | 2019-07-30 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms. Nat Commun, 11, 2020
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6F8Y
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![BU of 6f8y by Molmil](/molmil-images/mine/6f8y) | Crystal structure of P. abyssi Sua5 complexed with L-threonine | 分子名称: | THREONINE, Threonylcarbamoyl-AMP synthase | 著者 | Pichard-Kostuch, A, Zhang, W, Liger, D, Daugeron, M.C, Letoquart, J, Li de la Sierra-Gallay, I, Forterre, P, Collinet, B, van Tilbeurgh, H, Basta, T. | 登録日 | 2017-12-13 | 公開日 | 2018-04-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification. RNA, 24, 2018
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