5QRA

PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z1101755952

Summary for 5QRA

• Entry DOI: 10.2210/pdb5qra/pdb
• Group deposition: PanDDA analysis group deposition (G_1002078)
• Descriptor: 5-aminolevulinate synthase, erythroid-specific, mitochondrial, PYRIDOXAL-5'-PHOSPHATE, [(4R)-4-methyl-2,3,4,5-tetrahydro-1H-azepin-1-yl](1,3-thiazol-4-yl)methanone, ... (4 entities in total)
• Functional Keywords: sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 105217.70

Authors

Bezerra, G.A.,Foster, W.,Bailey, H.,Shrestha, L.,Krojer, T.,Talon, R.,Brandao-Neto, J.,Douangamath, A.,Nicola, B.B.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Brennan, P.E.,Yue, W.W. (deposition date: 2019-05-22, release date: 2019-08-07, Last modification date: 2024-03-06)

• Primary citation: Bezerra, G.A.,Foster, W.,Bailey, H.,Shrestha, L.,Krojer, T.,Talon, R.,Brandao-Neto, J.,Douangamath, A.,Nicola, B.B.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Brennan, P.E.,Yue, W.W.; PanDDA analysis group deposition; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.72 Å)