1HFP
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![BU of 1hfp by Molmil](/molmil-images/mine/1hfp) | COMPARISON OF TERNARY CRYSTAL COMPLEXES OF HUMAN DIHYDROFOLATE REDUCTASE WITH NADPH AND A CLASSICAL ANTITUMOR FUROPYRIMDINE | 分子名称: | DIHYDROFOLATE REDUCTASE, N-[4-[(2,4-DIAMINOFURO[2,3D]PYRIMIDIN-5-YL)METHYL]METHYLAMINO]-BENZOYL]-L-GLUTAMATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Blakley, R.L, Gangjee, A. | 登録日 | 1997-11-04 | 公開日 | 1998-01-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine. Anti-Cancer Drug Des., 13, 1998
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4P2K
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1SOI
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![BU of 1soi by Molmil](/molmil-images/mine/1soi) | CRYSTAL STRUCTURE OF NUDIX HYDROLASE DR1025 IN COMPLEX WITH SM+3 | 分子名称: | MutT/nudix family protein, SAMARIUM (III) ION | 著者 | Ranatunga, W, Hill, E.E, Mooster, J.L, Holbrook, E.L, Schulze-Gahmen, U, Xu, W, Bessman, M.J, Brenner, S.E, Holbrook, S.R, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2004-03-15 | 公開日 | 2004-05-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Studies of the Nudix Hydrolase DR1025 From Deinococcus radiodurans and its Ligand Complexes. J.Mol.Biol., 339, 2004
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7YRE
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![BU of 7yre by Molmil](/molmil-images/mine/7yre) | Crystal structure of a bright green fluorescent protein (StayGold) with triple mutations (N137A, Q140S, Y187F) in jellyfish Cytaeis uchidae from Biortus | 分子名称: | 1,2-ETHANEDIOL, staygold(N137A,Q140S,Y187F) | 著者 | Wu, J, Wang, F, Gui, W, Cheng, W, Yang, Y. | 登録日 | 2022-08-09 | 公開日 | 2023-08-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of a bright green fluorescent protein (StayGold) with triple mutations (N137A, Q140S, Y187F) in jellyfish Cytaeis uchidae from Biortus To Be Published
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3ICC
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![BU of 3icc by Molmil](/molmil-images/mine/3icc) | Crystal structure of a putative 3-oxoacyl-(acyl carrier protein) reductase from Bacillus anthracis at 1.87 A resolution | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Hou, J, Chruszcz, M, Zheng, H, Cymborowski, M, Luo, H.-B, Skarina, T, Gordon, S, Savchenko, A, Edwards, A.M, Anderson, W, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-07-17 | 公開日 | 2009-07-28 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structure of a short-chain dehydrogenase/reductase from Bacillus anthracis. Acta Crystallogr.,Sect.F, 68, 2012
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3IJW
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![BU of 3ijw by Molmil](/molmil-images/mine/3ijw) | Crystal structure of BA2930 in complex with CoA | 分子名称: | ACETYL COENZYME *A, Aminoglycoside N3-acetyltransferase, CHLORIDE ION, ... | 著者 | Klimecka, M.M, Chruszcz, M, Skarina, T, Onopryienko, O, Cymborowski, M, Savchenko, A, Edwards, A, Anderson, W, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-08-05 | 公開日 | 2009-10-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Analysis of a Putative Aminoglycoside N-Acetyltransferase from Bacillus anthracis. J.Mol.Biol., 410, 2011
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7QY3
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![BU of 7qy3 by Molmil](/molmil-images/mine/7qy3) | Crystal structure of the halohydrin dehalogenase HheG D114C mutant cross-linked with BMOE | 分子名称: | 1,1'-ethane-1,2-diylbis(1H-pyrrole-2,5-dione), Putative oxidoreductase, SULFATE ION | 著者 | Henke, S, Blankenfeldt, W, Schallmey, A. | 登録日 | 2022-01-27 | 公開日 | 2022-03-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Biocatalytically active and stable cross-linked enzyme crystals of halohydrin dehalogenase HheG by protein engineering Chemcatchem, 2022
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1HFQ
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![BU of 1hfq by Molmil](/molmil-images/mine/1hfq) | COMPARISON OF TERNARY CRYSTAL COMPLEXES OF HUMAN DIHYDROFOLATE REDUCTASE WITH NADPH AND A CLASSICAL ANTITUMOR FUROPYRIMDINE | 分子名称: | DIHYDROFOLATE REDUCTASE, N-[4-[(2,4-DIAMINOFURO[2,3D]PYRIMIDIN-5-YL)METHYL]METHYLAMINO]-BENZOYL]-L-GLUTAMATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Blakley, R.L, Gangjee, A. | 登録日 | 1997-11-04 | 公開日 | 1998-01-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine. Anti-Cancer Drug Des., 13, 1998
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7QV7
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![BU of 7qv7 by Molmil](/molmil-images/mine/7qv7) | Cryo-EM structure of Hydrogen-dependent CO2 reductase. | 分子名称: | Hydrogen dependent carbon dioxide reductase subunit FdhF, Hydrogen dependent carbon dioxide reductase subunit HycB3, Hydrogen dependent carbon dioxide reductase subunit HycB4, ... | 著者 | Dietrich, H.M, Righetto, R.D, Kumar, A, Wietrzynski, W, Schuller, S.K, Trischler, R, Wagner, J, Schwarz, F.M, Engel, B.D, Mueller, V, Schuller, J.M. | 登録日 | 2022-01-19 | 公開日 | 2022-07-06 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Membrane-anchored HDCR nanowires drive hydrogen-powered CO 2 fixation. Nature, 607, 2022
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7QAA
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![BU of 7qaa by Molmil](/molmil-images/mine/7qaa) | Crystal structure of RARalpha/RXRalpha ligand binding domain heterodimer in complex with BMS614 and oleic acid | 分子名称: | 4-[(4,4-DIMETHYL-1,2,3,4-TETRAHYDRO-[1,2']BINAPTHALENYL-7-CARBONYL)-AMINO]-BENZOIC ACID, Isoform Alpha-1-deltaBC of Retinoic acid receptor alpha, OLEIC ACID, ... | 著者 | le Maire, A, Vivat, V, Guee, L, Blanc, P, Malosse, C, Chamot-Rooke, J, Germain, P, Bourguet, w. | 登録日 | 2021-11-16 | 公開日 | 2022-10-05 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Design and in vitro characterization of RXR variants as tools to investigate the biological role of endogenous rexinoids. J.Mol.Endocrinol., 69, 2022
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1LXI
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![BU of 1lxi by Molmil](/molmil-images/mine/1lxi) | Refinement of BMP7 crystal structure | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BONE MORPHOGENETIC PROTEIN 7 | 著者 | Greenwald, J, Groppe, J, Kwiatkowski, W, Choe, S. | 登録日 | 2002-06-05 | 公開日 | 2003-04-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The BMP7/ActRII Extracellular Domain Complex Provides New Insights into
the Cooperative Nature of Receptor Assembly Mol.Cell, 11, 2003
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1HFR
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![BU of 1hfr by Molmil](/molmil-images/mine/1hfr) | COMPARISON OF TERNARY CRYSTAL COMPLEXES OF HUMAN DIHYDROFOLATE REDUCTASE WITH NADPH AND A CLASSICAL ANTITUMOR FUROPYRIMDINE | 分子名称: | DIHYDROFOLATE REDUCTASE, N-[4-[(2,4-DIAMINOFURO[2,3D]PYRIMIDIN-5-YL)METHYL]METHYLAMINO]-BENZOYL]-L-GLUTAMATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Blakley, R.L, Gangjee, A. | 登録日 | 1997-11-04 | 公開日 | 1998-01-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine. Anti-Cancer Drug Des., 13, 1998
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7ZS7
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![BU of 7zs7 by Molmil](/molmil-images/mine/7zs7) | Crystal structure of human cathepsin L with covalently bound calpain inhibitor VI | 分子名称: | (2S)-2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-[(2S)-4-methyl-1-oxidanyl-pentan-2-yl]butanamide, ACETATE ION, Cathepsin L, ... | 著者 | Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. | 登録日 | 2022-05-06 | 公開日 | 2023-05-17 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 2024
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1S1E
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![BU of 1s1e by Molmil](/molmil-images/mine/1s1e) | Crystal Structure of Kv Channel-interacting protein 1 (KChIP-1) | 分子名称: | CALCIUM ION, Kv channel interacting protein 1 | 著者 | Scannevin, R.H, Wang, K.-W, Jow, F, Megules, J, Kopsco, D.C, Edris, W, Carroll, K.C, Lu, Q, Xu, W.-X, Xu, Z.-B, Katz, A.H, Olland, S, Lin, L, Taylor, M, Stahl, M, Malakian, K, Somers, W, Mosyak, L, Bowlby, M.R, Chanda, P, Rhodes, K.J. | 登録日 | 2004-01-06 | 公開日 | 2005-01-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1. Neuron, 41, 2004
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7QIG
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![BU of 7qig by Molmil](/molmil-images/mine/7qig) | Infectious mouse-adapted RML scrapie prion fibril purified from terminally-infected mouse brains | 分子名称: | Major prion protein | 著者 | Manka, S.W, Zhang, W, Wenborn, A, Betts, J, Joiner, S, Saibil, H.R, Collinge, J, Wadsworth, J.D.F. | 登録日 | 2021-12-14 | 公開日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | 2.7 angstrom cryo-EM structure of ex vivo RML prion fibrils. Nat Commun, 13, 2022
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2K24
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7POI
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![BU of 7poi by Molmil](/molmil-images/mine/7poi) | Prodomain bound BMP10 crystal form 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bone morphogenetic protein 10, D(-)-TARTARIC ACID | 著者 | Guo, J, Yu, M, Li, W. | 登録日 | 2021-09-09 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10. Nat Commun, 13, 2022
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7POJ
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![BU of 7poj by Molmil](/molmil-images/mine/7poj) | Prodomain bound BMP10 crystal form 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bone morphogenetic protein 10, TETRAETHYLENE GLYCOL | 著者 | Guo, J, Yu, M, Li, W. | 登録日 | 2021-09-09 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10. Nat Commun, 13, 2022
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7ZXA
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![BU of 7zxa by Molmil](/molmil-images/mine/7zxa) | Crystal structure of human cathepsin L with covalently bound aloxistatin (E-64D) | 分子名称: | 1,2-ETHANEDIOL, Cathepsin L, DI(HYDROXYETHYL)ETHER, ... | 著者 | Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. | 登録日 | 2022-05-20 | 公開日 | 2023-05-31 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
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7PPC
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![BU of 7ppc by Molmil](/molmil-images/mine/7ppc) | Ternary signalling complex of BMP10 bound to ALK1 and BMPRII | 分子名称: | Bone morphogenetic protein 10, Bone morphogenetic protein receptor type-2, Serine/threonine-protein kinase receptor R3 | 著者 | Guo, J, Yu, M, Read, R.J, Li, W. | 登録日 | 2021-09-13 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10. Nat Commun, 13, 2022
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7PPB
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7Q18
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![BU of 7q18 by Molmil](/molmil-images/mine/7q18) | Beta-lactoglobulin mutant FAF (I56F/L39A/M107F), unliganded form | 分子名称: | Beta-lactoglobulin, SULFATE ION | 著者 | Loch, J.I, Cymborowski, M.T, Minor, W, Lewinski, K. | 登録日 | 2021-10-18 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.804 Å) | 主引用文献 | New ligand-binding sites identified in the crystal structures of [beta]-lactoglobulin complexes with desipramine Iucrj, 9, 2022
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7PPA
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![BU of 7ppa by Molmil](/molmil-images/mine/7ppa) | High resolution structure of bone morphogenetic protein receptor type II (BMPRII) extracellular domain in complex with BMP10 | 分子名称: | Bone morphogenetic protein 10, Bone morphogenetic protein receptor type-2, GLYCEROL | 著者 | Guo, J, Yu, M, Read, R.J, Li, W. | 登録日 | 2021-09-13 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10. Nat Commun, 13, 2022
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8A4V
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![BU of 8a4v by Molmil](/molmil-images/mine/8a4v) | Crystal structure of human cathepsin L with covalently bound E-64 | 分子名称: | Cathepsin L, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | 著者 | Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. | 登録日 | 2022-06-13 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
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8A4W
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![BU of 8a4w by Molmil](/molmil-images/mine/8a4w) | Crystal structure of human cathepsin L with covalently bound Cathepsin L inhibitor IV | 分子名称: | 1,2-ETHANEDIOL, Cathepsin L, DI(HYDROXYETHYL)ETHER, ... | 著者 | Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. | 登録日 | 2022-06-13 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
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